Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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Validation data
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- Product number
- 20883-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20883-1-AP, RRID:AB_10897158
- Product name
- EPHB4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated EPHB4 antibody (Cat. #20883-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The application of tissue-engineered fish swim bladder vascular graft.
Intermittent parathyroid hormone promotes cementogenesis via ephrinB2-EPHB4 forward signaling.
The role of EphB4/ephrinB2 signaling in root repair after orthodontically-induced root resorption.
Extracellular signal-regulated kinase inhibition prevents venous adaptive remodeling via regulation of Eph-B4.
Sanguinarine combats hypoxia-induced activation of EphB4 and HIF-1α pathways in breast cancer.
Adult Human Vein Grafts Retain Plasticity of Vessel Identity.
Kinome multigenic panel identified novel druggable EPHB4-V871I somatic variant in high-risk neuroblastoma.
Immunohistochemical assessment of Eph/ephrin expression in oral squamous cell carcinoma and precursor lesions.
Targeting the Eph/Ephrin System as Anti-Inflammatory Strategy in IBD.
Low-level blast exposure disrupts gliovascular and neurovascular connections and induces a chronic vascular pathology in rat brain.
Tumor necrosis factor-alpha inhibits osteogenic differentiation of pre-osteoblasts by downregulation of EphB4 signaling via activated nuclear factor-kappaB signaling pathway.
Near infrared light mediated photochemotherapy for efficiently treating deep orthotopic tumors guided by ultrasound imaging.
Low concentrations of TNF-α promote osteogenic differentiation via activation of the ephrinB2-EphB4 signalling pathway.
Specific Photothermal Ablation Therapy of Endometriosis by Targeting Delivery of Gold Nanospheres.
Bai H, Sun P, Wu H, Wei S, Xie B, Wang W, Hou Y, Li J, Dardik A, Li Z
Communications biology 2021 Oct 5;4(1):1153
Communications biology 2021 Oct 5;4(1):1153
Intermittent parathyroid hormone promotes cementogenesis via ephrinB2-EPHB4 forward signaling.
Li T, Wang H, Lv C, Huang L, Zhang C, Zhou C, Zou S, Duan P
Journal of cellular physiology 2021 Mar;236(3):2070-2086
Journal of cellular physiology 2021 Mar;236(3):2070-2086
The role of EphB4/ephrinB2 signaling in root repair after orthodontically-induced root resorption.
Li T, Wang H, Liu R, Wang X, Huang L, Wu Z, Yin X, Zou S, Duan P
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2021 Mar;159(3):e217-e232
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 2021 Mar;159(3):e217-e232
Extracellular signal-regulated kinase inhibition prevents venous adaptive remodeling via regulation of Eph-B4.
Guo Y, Zhu F, Zhang X, Wu G, Fu P, Yang J
Vascular 2021 Mar 11;:1708538121999854
Vascular 2021 Mar 11;:1708538121999854
Sanguinarine combats hypoxia-induced activation of EphB4 and HIF-1α pathways in breast cancer.
Su Q, Wang J, Wu Q, Ullah A, Ghauri MA, Sarwar A, Chen L, Liu F, Zhang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153503
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153503
Adult Human Vein Grafts Retain Plasticity of Vessel Identity.
Bai H, Wang Z, Li M, Sun P, Wei S, Wang Z, Xing Y, Dardik A
Annals of vascular surgery 2020 Oct;68:468-475
Annals of vascular surgery 2020 Oct;68:468-475
Kinome multigenic panel identified novel druggable EPHB4-V871I somatic variant in high-risk neuroblastoma.
Andolfo I, Lasorsa VA, Manna F, Rosato BE, Formicola D, Iolascon A, Capasso M
Journal of cellular and molecular medicine 2020 Jun;24(11):6459-6471
Journal of cellular and molecular medicine 2020 Jun;24(11):6459-6471
Immunohistochemical assessment of Eph/ephrin expression in oral squamous cell carcinoma and precursor lesions.
Saito H, Oikawa M, Kouketsu A, Takahashi T, Kumamoto H
Odontology 2020 Apr;108(2):166-173
Odontology 2020 Apr;108(2):166-173
Targeting the Eph/Ephrin System as Anti-Inflammatory Strategy in IBD.
Grandi A, Zini I, Palese S, Giorgio C, Tognolini M, Marchesani F, Bruno S, Flammini L, Cantoni AM, Castelli R, Lodola A, Fusari A, Barocelli E, Bertoni S
Frontiers in pharmacology 2019;10:691
Frontiers in pharmacology 2019;10:691
Low-level blast exposure disrupts gliovascular and neurovascular connections and induces a chronic vascular pathology in rat brain.
Gama Sosa MA, De Gasperi R, Perez Garcia GS, Perez GM, Searcy C, Vargas D, Spencer A, Janssen PL, Tschiffely AE, McCarron RM, Ache B, Manoharan R, Janssen WG, Tappan SJ, Hanson RW, Gandy S, Hof PR, Ahlers ST, Elder GA
Acta neuropathologica communications 2019 Jan 9;7(1):6
Acta neuropathologica communications 2019 Jan 9;7(1):6
Tumor necrosis factor-alpha inhibits osteogenic differentiation of pre-osteoblasts by downregulation of EphB4 signaling via activated nuclear factor-kappaB signaling pathway.
Wang LM, Zhao N, Zhang J, Sun QF, Yang CZ, Yang PS
Journal of periodontal research 2018 Feb;53(1):66-72
Journal of periodontal research 2018 Feb;53(1):66-72
Near infrared light mediated photochemotherapy for efficiently treating deep orthotopic tumors guided by ultrasound imaging.
Wang Z, Xuan S, Qiu W, Zhu J, Guo X, Li W, Zhang H, Zhu X, Du YZ, You J
Drug delivery 2017 Nov;24(1):1441-1452
Drug delivery 2017 Nov;24(1):1441-1452
Low concentrations of TNF-α promote osteogenic differentiation via activation of the ephrinB2-EphB4 signalling pathway.
Wang L, Zhang J, Wang C, Qi Y, Du M, Liu W, Yang C, Yang P
Cell proliferation 2017 Feb;50(1)
Cell proliferation 2017 Feb;50(1)
Specific Photothermal Ablation Therapy of Endometriosis by Targeting Delivery of Gold Nanospheres.
Guo X, Li W, Zhou J, Hou W, Wen X, Zhang H, Kong F, Luo L, Li Q, Du Y, You J
Small (Weinheim an der Bergstrasse, Germany) 2017 Apr;13(15)
Small (Weinheim an der Bergstrasse, Germany) 2017 Apr;13(15)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 20883-1-AP(EPHB4 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human placenta using 20883-1-AP(EPHB4 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human placenta using 20883-1-AP(EPHB4 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The EPHB4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human EPHB4. This antibody recognizes human,mouse,rat antigen. The EPHB4 antibody has been validated for the following applications: ELISA, WB, IHC, FC analysis.