11115-1-AP

antibody from Proteintech Group

Targeting: DDX3X DBX, DDX14, DDX3, HLP2

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

11115-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#11115-1-AP, RRID:AB_10896499

Product name

DDX3 antibody

Antibody type

Polyclonal

Description

KD/KO validated DDX3 antibody (Cat. #11115-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

DEAD-Box Helicase 3 X-Linked Promotes Metastasis by Inducing Epithelial-Mesenchymal Transition via p62/Sequestosome-1.

Zheng Y, Xu B, Zhao Y, Yang S, Wang S, Ma L, Dong L
Digestive diseases and sciences 2021 Nov;66(11):3893-3902

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Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway.

Hao W, Hao C, Wu C, Xu Y, Wu S, Lu X, Yang J, Jin C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112591

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DDX3X deficiency alleviates LPS-induced H9c2 cardiomyocytes pyroptosis by suppressing activation of NLRP3 inflammasome.

Feng D, Guo L, Liu J, Song Y, Ma X, Hu H, Liu J, Hao E
Experimental and therapeutic medicine 2021 Dec;22(6):1389

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CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation.

Cheng W, Wang S, Zhang Z, Morgens DW, Hayes LR, Lee S, Portz B, Xie Y, Nguyen BV, Haney MS, Yan S, Dong D, Coyne AN, Yang J, Xian F, Cleveland DW, Qiu Z, Rothstein JD, Shorter J, Gao FB, Bassik MC, Sun S
Neuron 2019 Dec 4;104(5):885-898.e8

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Tumor-suppressive miRNA-135a inhibits breast cancer cell proliferation by targeting ELK1 and ELK3 oncogenes.

Ahmad A, Zhang W, Wu M, Tan S, Zhu T
Genes & genomics 2018 Mar;40(3):243-251

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(DEAD)-box RNA helicase 3 modulates NF-κB signal pathway by controlling the phosphorylation of PP2A-C subunit.

Wang X, Wang R, Luo M, Li C, Wang HX, Huan CC, Qu YR, Liao Y, Mao X
Oncotarget 2017 May 16;8(20):33197-33213

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

C6 cells were subjected to SDS PAGE followed by western blot with 11115-1-AP(DDX3 antibody) at dilution of 1:400

Sample type

cell line

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

The DDX3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DDX3. This antibody recognizes human,mouse,rat antigen. The DDX3 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.

Appendix

11115-1-AP.pdf

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Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human cervical cancer using 11115-1-AP(DDX3 antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue