BS8482

antibody from Bioworld Technology, Inc
Targeting: DDX3X DBX, DDX14, DDX3, HLP2
Provider product page for BS8482
Western blot
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
BS8482 - Provider product page
Provider
Bioworld Technology, Inc
Product name
DDX3 polyclonal antibody
Antibody type
Polyclonal
Antigen
ATP-dependent RNA helicase DDX3X; DEAD box protein 3, X-chromosomal; DEAD box, X isoform; Helicase-like protein 2; HLP2; DDX3X; DBX; DDX3
Description
DDX3 contains all of the motifs of the DEAD box family of RNA helicases, including the Asp/Glu/Ala/Asp sequence that gives the protein family its name and distinguishes it from other RNA helicases. DDX3 is localized to the X chromosome and has a highly conserved functional homolog (DBY) on the Y chromosome. DDX3 is thought to be involved in RNA splicing, RNA transport, and translation initiation. It is also involved in cell growth control and is deregulated in hepatitis virus associated hepatocellular carcinoma. Recent experiments suppressing DDX3 expression blocked HIV1 RNA export from the nucleus, suggesting that DDX3 functions as a shuttling protein that transports the HIV1 protein Rev and its cofactor CRM1 from the nucleus to the cytoplasm.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
DDX3X protein structure - BS8482 shown in red.