FNab08787

antibody from FineTest Biotech

Targeting: TMEM59 C1orf8, HSPC001

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ELISA

Immunocytochemistry

Immunohistochemistry

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Validation data

Product number: FNab08787 - Provider product page
Provider: FineTest Biotech
Product name: TMEM59 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3(MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: transmembrane protein 59
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

TMEM59 protein structure - FNab08787 shown in red.