Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 17116-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17116-1-AP, RRID:AB_2299053
- Product name
- OMA1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated OMA1 antibody (Cat. #17116-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Niclosamide inhibits ovarian carcinoma growth by interrupting cellular bioenergetics.
A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol.
Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations.
Reciprocal Roles of Tom7 and OMA1 during Mitochondrial Import and Activation of PINK1.
Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.
Laminar shear stress promotes mitochondrial homeostasis in endothelial cells.
Adult-onset obesity is triggered by impaired mitochondrial gene expression.
Mitochondrial Optic Atrophy (OPA) 1 Processing Is Altered in Response to Neonatal Hypoxic-Ischemic Brain Injury.
The Genomic Landscape of Renal Oncocytoma Identifies a Metabolic Barrier to Tumorigenesis.
Shangguan F, Liu Y, Ma L, Qu G, Lv Q, An J, Yang S, Lu B, Cao Q
Journal of Cancer 2020;11(12):3454-3466
Journal of Cancer 2020;11(12):3454-3466
A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol.
Fessler E, Eckl EM, Schmitt S, Mancilla IA, Meyer-Bender MF, Hanf M, Philippou-Massier J, Krebs S, Zischka H, Jae LT
Nature 2020 Mar;579(7799):433-437
Nature 2020 Mar;579(7799):433-437
Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations.
Liu YT, Huang X, Nguyen D, Shammas MK, Wu BP, Dombi E, Springer DA, Poulton J, Sekine S, Narendra DP
Human molecular genetics 2020 Jun 3;29(9):1547-1567
Human molecular genetics 2020 Jun 3;29(9):1547-1567
Reciprocal Roles of Tom7 and OMA1 during Mitochondrial Import and Activation of PINK1.
Sekine S, Wang C, Sideris DP, Bunker E, Zhang Z, Youle RJ
Molecular cell 2019 Mar 7;73(5):1028-1043.e5
Molecular cell 2019 Mar 7;73(5):1028-1043.e5
Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.
Aulas A, Lyons SM, Fay MM, Anderson P, Ivanov P
Cell death & disease 2018 Nov 13;9(11):1129
Cell death & disease 2018 Nov 13;9(11):1129
Laminar shear stress promotes mitochondrial homeostasis in endothelial cells.
Wu LH, Chang HC, Ting PC, Wang DL
Journal of cellular physiology 2018 Jun;233(6):5058-5069
Journal of cellular physiology 2018 Jun;233(6):5058-5069
Adult-onset obesity is triggered by impaired mitochondrial gene expression.
Perks KL, Ferreira N, Richman TR, Ermer JA, Kuznetsova I, Shearwood AJ, Lee RG, Viola HM, Johnstone VPA, Matthews V, Hool LC, Rackham O, Filipovska A
Science advances 2017 Aug;3(8):e1700677
Science advances 2017 Aug;3(8):e1700677
Mitochondrial Optic Atrophy (OPA) 1 Processing Is Altered in Response to Neonatal Hypoxic-Ischemic Brain Injury.
Baburamani AA, Hurling C, Stolp H, Sobotka K, Gressens P, Hagberg H, Thornton C
International journal of molecular sciences 2015 Sep 17;16(9):22509-26
International journal of molecular sciences 2015 Sep 17;16(9):22509-26
The Genomic Landscape of Renal Oncocytoma Identifies a Metabolic Barrier to Tumorigenesis.
Joshi S, Tolkunov D, Aviv H, Hakimi AA, Yao M, Hsieh JJ, Ganesan S, Chan CS, White E
Cell reports 2015 Dec 1;13(9):1895-908
Cell reports 2015 Dec 1;13(9):1895-908
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The OMA1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human OMA1. This antibody recognizes human, mouse, rat antigen. The OMA1 antibody has been validated for the following applications: ELISA, WB analysis.