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- Antigen structure
- References [4]
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- Immunohistochemistry [1]
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- Product number
- ABIN2840328 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-DNA Cross-Link Repair 1B, PSO2 Homolog (S. Cerevisiae) (DCLRE1B) (AA 208-236), (Center) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 208-236, Center
- Antibody clone number
- RB26835
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleases.
Snm1B/Apollo mediates replication fork collapse and S Phase checkpoint activation in response to DNA interstrand cross-links.
Human SNM1B is required for normal cellular response to both DNA interstrand crosslink-inducing agents and ionizing radiation.
DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation.
Sengerová B, Allerston CK, Abu M, Lee SY, Hartley J, Kiakos K, Schofield CJ, Hartley JA, Gileadi O, McHugh PJ
The Journal of biological chemistry 2012 Jul 27;287(31):26254-67
The Journal of biological chemistry 2012 Jul 27;287(31):26254-67
Snm1B/Apollo mediates replication fork collapse and S Phase checkpoint activation in response to DNA interstrand cross-links.
Bae JB, Mukhopadhyay SS, Liu L, Zhang N, Tan J, Akhter S, Liu X, Shen X, Li L, Legerski RJ
Oncogene 2008 Aug 28;27(37):5045-56
Oncogene 2008 Aug 28;27(37):5045-56
Human SNM1B is required for normal cellular response to both DNA interstrand crosslink-inducing agents and ionizing radiation.
Demuth I, Digweed M, Concannon P
Oncogene 2004 Nov 11;23(53):8611-8
Oncogene 2004 Nov 11;23(53):8611-8
DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation.
Ishiai M, Kimura M, Namikoshi K, Yamazoe M, Yamamoto K, Arakawa H, Agematsu K, Matsushita N, Takeda S, Buerstedde JM, Takata M
Molecular and cellular biology 2004 Dec;24(24):10733-41
Molecular and cellular biology 2004 Dec;24(24):10733-41
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
