340304

antibody from BioLegend
Targeting: FCRL5 BXMAS1, CD307e, FCRH5, IRTA2
Provider product page for 340304

Antibody data

Product number
340304 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#340304, RRID:AB_2104588
Product name
PE anti-human CD307e (FcRL5)
Antibody type
Monoclonal
Antigen
P815 cells transfected with FcRL5
Description
FcRL5, also known as CD307e, CD307, IRTA2, FcRH5 and BXMAS1, is a 106kD type I transmembrane glycoprotein composed of 6-8 extracellular Ig like C2 domains and 2 cytoplasmic ITIM motifs. The FcRL5 gene is located on chromosome 1q21 and is normally expressed by tonsillar plasma cells and germinal center B cells. It has been suggested that FcRL5 contributes to B cell maturation and B cell receptor modulation. The identification of FcRL5 on a number of transformed cell types including hairy cell leukemia, mantle cell lymphoma, chronic lymphocytic lymphoma and Burkitt’s lymphoma has prompted interest in it as a potential biomarker or target for immunotherapy. FcRL5 binds all aggregated IgG isotypes.
Reactivity
Human
Host
Mouse
Conjugate
Yellow dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
FCRL5 protein structure - 340304 shown in red.