CABT-BL877

antibody from Creative Diagnostics

Targeting: CCDC88A APE, FLJ10392, GIV, GRDN, HkRP1, KIAA1212

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-BL877

Provider

Creative Diagnostics

Product name

Anti-CCDC88A polyclonal antibody

Antibody type

Polyclonal

Description

This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Storage

Store at -20°C. Stable for 12 months at -20°C