Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN2840099 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-N-Acetyltransferase 8 (NAT8) (AA 110-138), (Center) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 110-138, Center
- Antibody clone number
- RB25556
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references The endoplasmic reticulum-based acetyltransferases, ATase1 and ATase2, associate with the oligosaccharyltransferase to acetylate correctly folded polypeptides.
Biochemical inhibition of the acetyltransferases ATase1 and ATase2 reduces β-secretase (BACE1) levels and Aβ generation.
Two endoplasmic reticulum (ER)/ER Golgi intermediate compartment-based lysine acetyltransferases post-translationally regulate BACE1 levels.
N-acetyltransferase 8, a positional candidate for blood pressure and renal regulation: resequencing, association and in silico study.
High-throughput mapping of a dynamic signaling network in mammalian cells.
Ding Y, Dellisanti CD, Ko MH, Czajkowski C, Puglielli L
The Journal of biological chemistry 2014 Nov 14;289(46):32044-55
The Journal of biological chemistry 2014 Nov 14;289(46):32044-55
Biochemical inhibition of the acetyltransferases ATase1 and ATase2 reduces β-secretase (BACE1) levels and Aβ generation.
Ding Y, Ko MH, Pehar M, Kotch F, Peters NR, Luo Y, Salamat SM, Puglielli L
The Journal of biological chemistry 2012 Mar 9;287(11):8424-33
The Journal of biological chemistry 2012 Mar 9;287(11):8424-33
Two endoplasmic reticulum (ER)/ER Golgi intermediate compartment-based lysine acetyltransferases post-translationally regulate BACE1 levels.
Ko MH, Puglielli L
The Journal of biological chemistry 2009 Jan 23;284(4):2482-92
The Journal of biological chemistry 2009 Jan 23;284(4):2482-92
N-acetyltransferase 8, a positional candidate for blood pressure and renal regulation: resequencing, association and in silico study.
Juhanson P, Kepp K, Org E, Veldre G, Kelgo P, Rosenberg M, Viigimaa M, Laan M
BMC medical genetics 2008 Apr 10;9:25
BMC medical genetics 2008 Apr 10;9:25
High-throughput mapping of a dynamic signaling network in mammalian cells.
Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, Donovan RS, Shinjo F, Liu Y, Dembowy J, Taylor IW, Luga V, Przulj N, Robinson M, Suzuki H, Hayashizaki Y, Jurisica I, Wrana JL
Science (New York, N.Y.) 2005 Mar 11;307(5715):1621-5
Science (New York, N.Y.) 2005 Mar 11;307(5715):1621-5
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
