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- Antibody Data
- Antigen structure
- References [15]
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- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [3]
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- Product number
- GTX100027 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX100027, RRID:AB_1240639
- Product name
- CXCR7 antibody [C1C2], Internal
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse
- Host
- Rabbit
Submitted references CXCR7 promotes melanoma tumorigenesis via Src kinase signaling.
Enzalutamide and CXCR7 inhibitor combination treatment suppresses cell growth and angiogenic signaling in castration-resistant prostate cancer models.
CXCR7 maintains osteosarcoma invasion after CXCR4 suppression in bone marrow microenvironment.
CXCR4/CXCR7/CXCL12 axis promotes an invasive phenotype in medullary thyroid carcinoma.
β-Arrestin-2 Counters CXCR7-Mediated EGFR Transactivation and Proliferation.
Identification of Target Genes Involved in Wound Healing Angiogenesis of Endothelial Cells with the Treatment of a Chinese 2-Herb Formula.
Chemokine receptor CXCR7 is a functional receptor for CXCL12 in brain endothelial cells.
Migration, proliferation, and differentiation of cord blood mesenchymal stromal cells treated with histone deacetylase inhibitor valproic Acid.
Close correlation between CXCR4 and VEGF expression and frequent CXCR7 expression in rhabdomyosarcoma
Genome-wide approaches reveal functional vascular endothelial growth factor (VEGF)-inducible nuclear factor of activated T cells (NFAT) c1 binding to angiogenesis-related genes in the endothelium.
The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation.
Llama-derived single variable domains (nanobodies) directed against chemokine receptor CXCR7 reduce head and neck cancer cell growth in vivo.
SDF-1α/CXCR4 signaling mediates digit tip regeneration promoted by BMP-2.
Inhibition of astroglial NF-κB enhances oligodendrogenesis following spinal cord injury.
The IL-8-regulated chemokine receptor CXCR7 stimulates EGFR signaling to promote prostate cancer growth.
Xu S, Tang J, Wang C, Liu J, Fu Y, Luo Y
Cell death & disease 2019 Feb 25;10(3):191
Cell death & disease 2019 Feb 25;10(3):191
Enzalutamide and CXCR7 inhibitor combination treatment suppresses cell growth and angiogenic signaling in castration-resistant prostate cancer models.
Luo Y, Azad AK, Karanika S, Basourakos SP, Zuo X, Wang J, Yang L, Yang G, Korentzelos D, Yin J, Park S, Zhang P, Campbell JJ, Schall TJ, Cao G, Li L, Thompson TC
International journal of cancer 2018 May 15;142(10):2163-2174
International journal of cancer 2018 May 15;142(10):2163-2174
CXCR7 maintains osteosarcoma invasion after CXCR4 suppression in bone marrow microenvironment.
Han Y, Wu C, Wang J, Liu N
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 May;39(5):1010428317701631
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 May;39(5):1010428317701631
CXCR4/CXCR7/CXCL12 axis promotes an invasive phenotype in medullary thyroid carcinoma.
Werner TA, Forster CM, Dizdar L, Verde PE, Raba K, Schott M, Knoefel WT, Krieg A
British journal of cancer 2017 Dec 5;117(12):1837-1845
British journal of cancer 2017 Dec 5;117(12):1837-1845
β-Arrestin-2 Counters CXCR7-Mediated EGFR Transactivation and Proliferation.
Kallifatidis G, Munoz D, Singh RK, Salazar N, Hoy JJ, Lokeshwar BL
Molecular cancer research : MCR 2016 May;14(5):493-503
Molecular cancer research : MCR 2016 May;14(5):493-503
Identification of Target Genes Involved in Wound Healing Angiogenesis of Endothelial Cells with the Treatment of a Chinese 2-Herb Formula.
Tam JC, Ko CH, Koon CM, Cheng Z, Lok WH, Lau CP, Leung PC, Fung KP, Chan WY, Lau CB
PloS one 2015;10(10):e0139342
PloS one 2015;10(10):e0139342
Chemokine receptor CXCR7 is a functional receptor for CXCL12 in brain endothelial cells.
Liu Y, Carson-Walter E, Walter KA
PloS one 2014;9(8):e103938
PloS one 2014;9(8):e103938
Migration, proliferation, and differentiation of cord blood mesenchymal stromal cells treated with histone deacetylase inhibitor valproic Acid.
Marquez-Curtis LA, Qiu Y, Xu A, Janowska-Wieczorek A
Stem cells international 2014;2014:610495
Stem cells international 2014;2014:610495
Close correlation between CXCR4 and VEGF expression and frequent CXCR7 expression in rhabdomyosarcoma
Miyoshi K, Kohashi K, Fushimi F, Yamamoto H, Kishimoto J, Taguchi T, Iwamoto Y, Oda Y
Human Pathology 2014 September;45(9):1900-1909
Human Pathology 2014 September;45(9):1900-1909
Genome-wide approaches reveal functional vascular endothelial growth factor (VEGF)-inducible nuclear factor of activated T cells (NFAT) c1 binding to angiogenesis-related genes in the endothelium.
Suehiro J, Kanki Y, Makihara C, Schadler K, Miura M, Manabe Y, Aburatani H, Kodama T, Minami T
The Journal of biological chemistry 2014 Oct 17;289(42):29044-59
The Journal of biological chemistry 2014 Oct 17;289(42):29044-59
The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation.
Salazar N, Muñoz D, Kallifatidis G, Singh RK, Jordà M, Lokeshwar BL
Molecular cancer 2014 Aug 28;13:198
Molecular cancer 2014 Aug 28;13:198
Llama-derived single variable domains (nanobodies) directed against chemokine receptor CXCR7 reduce head and neck cancer cell growth in vivo.
Maussang D, Mujić-Delić A, Descamps FJ, Stortelers C, Vanlandschoot P, Stigter-van Walsum M, Vischer HF, van Roy M, Vosjan M, Gonzalez-Pajuelo M, van Dongen GA, Merchiers P, van Rompaey P, Smit MJ
The Journal of biological chemistry 2013 Oct 11;288(41):29562-72
The Journal of biological chemistry 2013 Oct 11;288(41):29562-72
SDF-1α/CXCR4 signaling mediates digit tip regeneration promoted by BMP-2.
Lee J, Marrero L, Yu L, Dawson LA, Muneoka K, Han M
Developmental biology 2013 Oct 1;382(1):98-109
Developmental biology 2013 Oct 1;382(1):98-109
Inhibition of astroglial NF-κB enhances oligodendrogenesis following spinal cord injury.
Bracchi-Ricard V, Lambertsen KL, Ricard J, Nathanson L, Karmally S, Johnstone J, Ellman DG, Frydel B, McTigue DM, Bethea JR
Journal of neuroinflammation 2013 Jul 23;10:92
Journal of neuroinflammation 2013 Jul 23;10:92
The IL-8-regulated chemokine receptor CXCR7 stimulates EGFR signaling to promote prostate cancer growth.
Singh RK, Lokeshwar BL
Cancer research 2011 May 1;71(9):3268-77
Cancer research 2011 May 1;71(9):3268-77
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 ?g of whole cell lysate) A: PC-3 B: U87-MG 10% SDS PAGE GTX100027 diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of paraformaldehyde-fixed human pancreatic cancer cell line, using CXCR7(GTX100027) antibody at 1:50 dilution. Blue: DAPI.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human gastric cancer, using CXCR7(GTX100027) antibody at 1:100 dilution.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded Human pancreatic tumor, using CXCR7(GTX100027) antibody at 1:100 dilution.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded Human pancreatic tumor, using CXCR7(GTX100027) antibody at 1:100 dilution.
