331101

antibody from BioLegend
Targeting: ACKR3 CMKOR1, CXCR7, GPR159, RDC1
Provider product page for 331101

Antibody data

Product number
331101 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#331101, RRID:AB_1027646
Product name
Purified anti-human/mouse CXCR7
Antibody type
Monoclonal
Antigen
Human CXCR7 transfectant
Description
CXCR7, also known as RDC1, belongs to a subgroup of C-X-C chemokine receptors, which are part of a large protein family of G protein-coupled receptors (GPCR).  CXCR7 binds with high-affinity to CXCL12/SDF-1 and CXCL11/I-TAC, which regulates the trafficking and activation of leukocytes. It is also a co-receptor for the entry of HIV-1. Binding of ligand to CXCR7 induces proliferation and migration of immature neurons, glia and their precursors.  CXCR7 expression occurs on a wide variety of tissues and cells including monocytes, B cells, T cells and mature dendritic cells.  Surface expression of CXCR7 was also reported to be on tumor cells, activated endothelial cells, fetal liver cells, and few other cell types.
Reactivity
Human, Mouse
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C.
ACKR3 protein structure - 331101 shown in red.