Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B1723 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-GCGR polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Glucagon receptor or GL-R (UniProt P47871) is encoded by the GCGR (also known as GGR) gene (Gene ID 2642) in human. Glucagon is a 29-amino acid peptide that stimulates glycogenolysis and gluconeogenesis in the liver to increase blood glucose. The receptor for glucagon is a class 2 (or class B) G protein-coupled receptor (GPCR) that signals through Gs to stimulate cAMP production. Mice lacking the glucagon receptor have mild hypoglycemia after fasting and exhibit hyperplasia of pancreatic alpha-cells. Because of its role in promoting hyperglycemia, the glucagon receptor presents a potential target for treatment of diabetes.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 _g
- Concentration
- Please refer to lot specific datasheet.
- Storage
- Stable for 1 year at 2-8°C from date of receipt.
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