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- Antibody Data
- Antigen structure
- References [1]
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- Western blot [1]
- Immunohistochemistry [4]
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- Product number
- NBP1-84881 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-84881, RRID:AB_11018199
- Product name
- Rabbit Polyclonal CDKL5 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human CDKL5 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.
Ricciardi S, Ungaro F, Hambrock M, Rademacher N, Stefanelli G, Brambilla D, Sessa A, Magagnotti C, Bachi A, Giarda E, Verpelli C, Kilstrup-Nielsen C, Sala C, Kalscheuer VM, Broccoli V
Nature cell biology 2012 Sep;14(9):911-23
Nature cell biology 2012 Sep;14(9):911-23
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CDKL5 Antibody [NBP1-84881] - Analysis in control (vector only transfected HEK293T lysate) and CDKL5 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CDKL5 Antibody [NBP1-84881] - Staining of human lung shows moderate nuclear positivity in macrophages.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CDKL5 Antibody [NBP1-84881] - Staining of human placenta shows moderate nuclear positivity in trophoblastic cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CDKL5 Antibody [NBP1-84881] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CDKL5 Antibody [NBP1-84881] - Staining of human testis shows moderate nuclear positivity in cells.
