BS6416
antibody from Bioworld Technology, Inc
Targeting: SMC1A
DXS423E, KIAA0178, SB1.8, SMC1L1, Smcb
Antibody data
- Antibody Data
- Antigen structure
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- Validations [0]
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- Product number
- BS6416 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- SMC 1 (phospho S957) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic phosphopeptide derived from human SMC 1 around the phosphorylation site of Serine 957.
- Description
- The SMC (structural maintenance of chromosomes) family of proteins form heterodimeric complexes that modulate sister chromatid cohesion and chromosome condensation for mitosis. The two distinct classes of SMC protein complexes are comprised of SMC1 (also designated SB1.8) along with SMC3 (also designated HCAP for human chromosome-associated protein or Bama-can), and SMC2 (also designated hCAP-E) along with SMC4 (also designated hCAP-C). The SMC1/SMC3 complex is required for metaphase progression in mitotic cells and functions independently of the SMC2/SMC4 complex during the cell cycle. SMC1 is ubiqitiously expressed in various human tissues, including thymus, testis and colon. SMC3 is expressed as a nuclear protein in the colon, but can also occur as a secreted proteoglycan (called Bamacan) expressed in testis and brain. Bamacan contains several glycosylation sites and is thought to play a role in basement membrane physiology.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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