BS6416

antibody from Bioworld Technology, Inc
Targeting: SMC1A DXS423E, KIAA0178, SB1.8, SMC1L1, Smcb
Provider product page for BS6416
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6416 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SMC 1 (phospho S957) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human SMC 1 around the phosphorylation site of Serine 957.
Description
The SMC (structural maintenance of chromosomes) family of proteins form heterodimeric complexes that modulate sister chromatid cohesion and chromosome condensation for mitosis. The two distinct classes of SMC protein complexes are comprised of SMC1 (also designated SB1.8) along with SMC3 (also designated HCAP for human chromosome-associated protein or Bama-can), and SMC2 (also designated hCAP-E) along with SMC4 (also designated hCAP-C). The SMC1/SMC3 complex is required for metaphase progression in mitotic cells and functions independently of the SMC2/SMC4 complex during the cell cycle. SMC1 is ubiqitiously expressed in various human tissues, including thymus, testis and colon. SMC3 is expressed as a nuclear protein in the colon, but can also occur as a secreted proteoglycan (called Bamacan) expressed in testis and brain. Bamacan contains several glycosylation sites and is thought to play a role in basement membrane physiology.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SMC1A protein structure - BS6416 shown in red.