AF1849

antibody from Novus Biologicals

Targeting: NCR3 1C7, CD337, LY117, NKp30

Western blot (Data presented on provider website)

Antibody Data

Product number

AF1849

Provider

Novus Biologicals

Product name

Goat Polyclonal NKp30/NCR3 Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Detects human NKp30/NCR3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant human (rh) NKp80, rhNKp44 and rhNKp46 is observed.

Reactivity

Human

Host

Goat

Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

References

Submitted references

Homo-oligomerization of the activating natural killer cell receptor NKp30 ectodomain increases its binding affinity for cellular ligands.

Herrmann J, Berberich H, Hartmann J, Beyer S, Davies K, Koch J
The Journal of biological chemistry 2014 Jan 10;289(2):765-77

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The stalk domain and the glycosylation status of the activating natural killer cell receptor NKp30 are important for ligand binding.

Hartmann J, Tran TV, Kaudeer J, Oberle K, Herrmann J, Quagliano I, Abel T, Cohnen A, Gatterdam V, Jacobs A, Wollscheid B, Tampé R, Watzl C, Diefenbach A, Koch J
The Journal of biological chemistry 2012 Sep 7;287(37):31527-39