Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- FAB1849P-025 - Provider product page
- Provider
- R&D Systems
- Product name
- Human NKp30/NCR3 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human NKp30/NCR3 on cell transfectants and peripheral blood NK cells.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 210845
- Vial size
- 25 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Activated hepatic stellate cells impair NK cell anti-fibrosis capacity through a TGF-β-dependent emperipolesis in HBV cirrhotic patients.
Altered expression of miR-181a and miR-146a does not change the expression of surface NCRs in human NK cells.
Natural killer cells are characterized by the concomitantly increased interferon-γ and cytotoxicity in acute resolved hepatitis B patients.
Regulation of NK92-MI cell cytotoxicity by substance P.
A novel population of human CD56+ human leucocyte antigen D-related (HLA-DR+) colonic lamina propria cells is associated with inflammation in ulcerative colitis.
Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients.
Shi J, Zhao J, Zhang X, Cheng Y, Hu J, Li Y, Zhao X, Shang Q, Sun Y, Tu B, Shi L, Gao B, Wang FS, Zhang Z
Scientific reports 2017 Mar 14;7:44544
Scientific reports 2017 Mar 14;7:44544
Altered expression of miR-181a and miR-146a does not change the expression of surface NCRs in human NK cells.
Rady M, Watzl C, Claus M, Khorshid O, Mahran L, Abou-Aisha K
Scientific reports 2017 Feb 1;7:41381
Scientific reports 2017 Feb 1;7:41381
Natural killer cells are characterized by the concomitantly increased interferon-γ and cytotoxicity in acute resolved hepatitis B patients.
Zhao J, Li Y, Jin L, Zhang S, Fan R, Sun Y, Zhou C, Shang Q, Li W, Zhang Z, Wang FS
PloS one 2012;7(11):e49135
PloS one 2012;7(11):e49135
Regulation of NK92-MI cell cytotoxicity by substance P.
Fu WX, Qin B, Zhou AP, Yu QY, Huang QJ, Liang ZF
Scandinavian journal of immunology 2011 Aug;74(2):107-13
Scandinavian journal of immunology 2011 Aug;74(2):107-13
A novel population of human CD56+ human leucocyte antigen D-related (HLA-DR+) colonic lamina propria cells is associated with inflammation in ulcerative colitis.
Ng SC, Plamondon S, Al-Hassi HO, English N, Gellatly N, Kamm MA, Knight SC, Stagg AJ
Clinical and experimental immunology 2009 Nov;158(2):205-18
Clinical and experimental immunology 2009 Nov;158(2):205-18
Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients.
Cai L, Zhang Z, Zhou L, Wang H, Fu J, Zhang S, Shi M, Zhang H, Yang Y, Wu H, Tien P, Wang FS
Clinical immunology (Orlando, Fla.) 2008 Dec;129(3):428-37
Clinical immunology (Orlando, Fla.) 2008 Dec;129(3):428-37
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- Detection of NKp30/NCR3 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody (Catalog # FAB2408A) and either (A) Mouse Anti-Human NKp30/NCR3 PE-conjugated Monoclonal Antibody (Catalog # FAB1849P) or (B) Mouse IgG2A Phycoerythrin Isotype Control (Catalog # IC003P). View our protocol for Staining Membrane-associated Proteins.