325203

antibody from BioLegend
Targeting: NCR3 1C7, CD337, LY117, NKp30
Provider product page for 325203
ELISA
Flow cytometry
Blocking/Neutralizing

Antibody data

Product number
325203 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#325203, RRID:AB_756107
Product name
LEAF™ purified anti-human CD337 (NKp30) [P30-15]
Antibody type
Monoclonal
Antigen
Recombinant human NKp30
Description
The p30-15 monoclonal antibody recognizes CD337 also known as activating NK receptor NKp30 (NKp30), and natural cytotoxicity triggering receptor 3. NKp30 is a type I transmembrane protein, member of the natural cytotoxicity receptor family that contains one immunoglobulin-like domain. NKp30 has an apparent molecular weight of 30 kD and six isoforms are produced by alternative splicing. NKp30 is expressed on resting and activated NK cells. NKp30 enhances NK cell cytolysis of tumor cellts that are deficient in MHC class I molecules. NKp30 has been shown to associate with CD59 and TCRζ. The p30-15 antibody against human NKp30 has been shown to be useful for flow cytometry, stimulation of human NK cells via NKp30 in a redirected lysis assay, and blocking of NKp30 function in solution.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
50 µg
Concentration
1 mg/ml
Storage
The antibody solution should be stored undiluted at 4 °C. This LEAF™ solution contains no preservative; handle under aseptic conditions.
NCR3 protein structure - 325203 shown in red.