BS7188

antibody from Bioworld Technology, Inc

Targeting: DEFB4B DEFB4P

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS7188

Provider

Bioworld Technology, Inc

Product name

DEFB4 polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant full length Human DEFB4.

Description

ÉÇ-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, ÉÇ-defensins are developmentally regulated. Unlike the other previously described human ÉÇ-defensins, human ÉÇ-defensin 4 (hBD-4) expression is restricted to a few tissues, with highest expression in testis. A restricted pattern is also exhibited by mouse ÉÇ-defensin 4. Rat ÉÇ-defensin 4 (also desiganated BD-4, RBD-4, BD-2, and RBD-2) is developmentally regulated in the lung and is predominantly expressed in the lung and, to a lesser extent, in the trachea and tongue. It exhibits a regulation pattern similar to that of specific genes involved in host defense around the time of birth. The selectivity in both expression pattern and antimicrobial activity of human ÉÇ-defensin 4 suggests that it is best suited to act at the epithelial locations where it is expressed.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.