Tissue expression
Cell line expression
Protein structure
BCDIN3D
BCDIN3 domain containing RNA methyltransferaseThis gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5'-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The encoded protein contains an S-adenosylmethionine binding domain and uses the methyl group donor, S-adenosylmethionine. This gene is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. The encoded protein is thought to promote the cellular invasion of breast cancer cells, by downregulating the expression of tumor suppressor miRNAs through the dimethylation of the 5-monophosphate of the corresponding precursor miRNAs. [provided by RefSeq, Apr 2017]
Top validated antibodies |
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Atlas Antibodies | HPA039911 | Polyclonal |
WB
ICC
IHC
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Invitrogen Antibodies | PA5-58979 | Polyclonal |
WB
ICC
IHC
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antibodies-online | ABIN4283276 | Polyclonal |
WB
ICC
IHC
|
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Novus Biologicals | NBP1-85857 | Polyclonal |
WB
ICC
IHC
|
||
Abnova Corporation | PAB23458 | Polyclonal |
WB
IHC |
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Supportive data in Antibodypedia
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