Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS2131 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS2131, RRID:AB_1662150
- Product name
- ATF6B (S425) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 390-442 of Human ATF6B.
- Description
- ATF-6 is a member of the basic-leucine zipper family of transcription factors. Endoplasmic reticulum stress causes cleavage of transmembrane ATF-6 and transclocation of active ATF-6 to the nucleus. Soluble ATF-6 can exist as either an ATF-6ÉÇ homodimer or an ATF-6Ï«/ÉÇ heterodimer. Binding of the ATF-6ÉÇ homodimer or ATF-6Ï«/ÉÇ heterodimer to the nuclear transcription factor Y C (NF-YC) induces ER chaperone transcription.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of ATF6B (S425) pAb at 1:500 dilutionLane1:MCF-7 cell lysateLane2:Mouse liver tissue lysateLane3:Rat liver tissue lysate