DPABH-20827

antibody from Creative Diagnostics

Targeting: NUDT15 FLJ10956, MTH2

Western blot (Recommended by provider)

Antibody Data

Product number

DPABH-20827

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-20827, RRID:AB_2504186

Product name

Rabbit Anti-Human NUDT15 Polyclonal Antibody

Antibody type

Polyclonal

Description

This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50ul, 100ul

Storage

Store at -20°C. Avoid freeze / thaw cycles.