AMM03957G

antibody from Leading Biology
Targeting: PSMD10 p28
Provider product page for AMM03957G
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
AMM03957G - Provider product page
Provider
Leading Biology
Product name
PSMD10 Antibody (monoclonal) (M01)
Antibody type
Monoclonal
Description
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
4B5
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
PSMD10 protein structure - AMM03957G shown in red.