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- Product number
- NBP1-93863 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-93863, RRID:AB_11005892
- Product name
- Rabbit Polyclonal CCDC114 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human CCDC114 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references CCDC151 mutations cause primary ciliary dyskinesia by disruption of the outer dynein arm docking complex formation.
Splice-site mutations in the axonemal outer dynein arm docking complex gene CCDC114 cause primary ciliary dyskinesia.
Hjeij R, Onoufriadis A, Watson CM, Slagle CE, Klena NT, Dougherty GW, Kurkowiak M, Loges NT, Diggle CP, Morante NF, Gabriel GC, Lemke KL, Li Y, Pennekamp P, Menchen T, Konert F, Marthin JK, Mans DA, Letteboer SJ, Werner C, Burgoyne T, Westermann C, Rutman A, Carr IM, O'Callaghan C, Moya E, Chung EM, UK10K Consortium., Sheridan E, Nielsen KG, Roepman R, Bartscherer K, Burdine RD, Lo CW, Omran H, Mitchison HM
American journal of human genetics 2014 Sep 4;95(3):257-74
American journal of human genetics 2014 Sep 4;95(3):257-74
Splice-site mutations in the axonemal outer dynein arm docking complex gene CCDC114 cause primary ciliary dyskinesia.
Onoufriadis A, Paff T, Antony D, Shoemark A, Micha D, Kuyt B, Schmidts M, Petridi S, Dankert-Roelse JE, Haarman EG, Daniels JM, Emes RD, Wilson R, Hogg C, Scambler PJ, Chung EM, UK10K., Pals G, Mitchison HM
American journal of human genetics 2013 Jan 10;92(1):88-98
American journal of human genetics 2013 Jan 10;92(1):88-98
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CCDC114 Antibody [NBP1-93863] - Staining of human bronchus shows strong positivity in cilia in respiratory epithelial cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CCDC114 Antibody [NBP1-93863] - Staining of human cerebral cortex shows no positivity in neurons as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CCDC114 Antibody [NBP1-93863] - Staining of human fallopian tube shows strong positivity in cilia in glandular cells.
