BS1922

antibody from Bioworld Technology, Inc
Targeting: POLA1 NSX, p180, POLA
Provider product page for BS1922

Antibody data

Product number
BS1922 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS1922, RRID:AB_1662234
Product name
DNA pol Ï« (K111) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 81-130 of Human DNA pol Ï«.
Description
DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases. DNA pol Ï«, ÉÇ, Ñ´ and š÷ are involved in DNA replication and repair. DNA pol Ñ´ and DNA pol š÷ are multisubunit enzymes, with DNA pol Ñ´ consisting of two subunits: p125, which interacts with the sliding DNA clamp protein PCNA; and p50. The nuclear-encoded DNA pol ÎÛ is the only DNA polymerase required for the replication of the mitochondrial DNA. DNA pol šø is ubiquitously expressed in various tissues and mediates the cellular mechanism of damage-induced mutagenesis. DNA pol IJ is a DNA polymerase-helicase that binds ATP and is involved in the repair of interstrand crosslinks.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
POLA1 protein structure - BS1922 shown in red.