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LearnNBP1-90311
antibody from Novus Biologicals
Targeting: POGLUT1
9630046K23Rik, C3orf9, hCLP46, KDELCL1, KTELC1, MDS010, MDSRP, MGC32995, Rumi
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [3]
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- Product number
- NBP1-90311 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-90311, RRID:AB_11039955
- Product name
- Rabbit Polyclonal Protein O-Glucosyltransferase 1/POGLUT1/KTELC1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human Protein O-Glucosyltransferase 1/POGLUT1/KTELC1 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references POGLUT1 biallelic mutations cause myopathy with reduced satellite cells, α-dystroglycan hypoglycosylation and a distinctive radiological pattern.
RUMI is a novel negative prognostic marker and therapeutic target in non-small-cell lung cancer.
Mutations in POGLUT1, encoding protein O-glucosyltransferase 1, cause autosomal-dominant Dowling-Degos disease.
Servián-Morilla E, Cabrera-Serrano M, Johnson K, Pandey A, Ito A, Rivas E, Chamova T, Muelas N, Mongini T, Nafissi S, Claeys KG, Grewal RP, Takeuchi M, Hao H, Bönnemann C, Lopes Abath Neto O, Medne L, Brandsema J, Töpf A, Taneva A, Vilchez JJ, Tournev I, Haltiwanger RS, Takeuchi H, Jafar-Nejad H, Straub V, Paradas C
Acta neuropathologica 2020 Mar;139(3):565-582
Acta neuropathologica 2020 Mar;139(3):565-582
RUMI is a novel negative prognostic marker and therapeutic target in non-small-cell lung cancer.
Chammaa M, Malysa A, Redondo C, Jang H, Chen W, Bepler G, Fernandez-Valdivia R
Journal of cellular physiology 2018 Dec;233(12):9548-9562
Journal of cellular physiology 2018 Dec;233(12):9548-9562
Mutations in POGLUT1, encoding protein O-glucosyltransferase 1, cause autosomal-dominant Dowling-Degos disease.
Basmanav FB, Oprisoreanu AM, Pasternack SM, Thiele H, Fritz G, Wenzel J, Größer L, Wehner M, Wolf S, Fagerberg C, Bygum A, Altmüller J, Rütten A, Parmentier L, El Shabrawi-Caelen L, Hafner C, Nürnberg P, Kruse R, Schoch S, Hanneken S, Betz RC
American journal of human genetics 2014 Jan 2;94(1):135-43
American journal of human genetics 2014 Jan 2;94(1):135-43
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Protein O-Glucosyltransferase 1/POGLUT1/KTELC1 Antibody [NBP1-90311] - Analysis in control (vector only transfected HEK293T lysate) and POGLUT1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Protein O-Glucosyltransferase 1/POGLUT1/KTELC1 Antibody [NBP1-90311] - Staining of human placenta shows moderate cytoplasmic positivity in trophoblastic cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Protein O-Glucosyltransferase 1/POGLUT1/KTELC1 Antibody [NBP1-90311] - Staining of human kidney shows weak cytoplasmic positivity in cells in tubules.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Protein O-Glucosyltransferase 1/POGLUT1/KTELC1 Antibody [NBP1-90311] - Staining of human liver shows no positivity in hepatocytes as expected.
