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- References [3]
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- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- 10997-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10997-2-AP, RRID:AB_2299887
- Product name
- POLG2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated POLG2 antibody (Cat. #10997-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TFB2M and POLRMT are essential for mammalian mitochondrial DNA replication.
The accessory subunit of human DNA polymerase γ is required for mitochondrial DNA maintenance and is able to stabilize the catalytic subunit.
Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity.
Inatomi T, Matsuda S, Ishiuchi T, Do Y, Nakayama M, Abe S, Kasho K, Wanrooij S, Nakada K, Ichiyanagi K, Sasaki H, Yasukawa T, Kang D
Biochimica et biophysica acta. Molecular cell research 2022 Jan;1869(1):119167
Biochimica et biophysica acta. Molecular cell research 2022 Jan;1869(1):119167
The accessory subunit of human DNA polymerase γ is required for mitochondrial DNA maintenance and is able to stabilize the catalytic subunit.
Do Y, Matsuda S, Inatomi T, Nakada K, Yasukawa T, Kang D
Mitochondrion 2020 Jul;53:133-139
Mitochondrion 2020 Jul;53:133-139
Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity.
Zhao X, Sun K, Lan Z, Song W, Cheng L, Chi W, Chen J, Huo Y, Xu L, Liu X, Deng H, Siegenthaler JA, Chen L
Scientific reports 2017 Apr 11;7:46344
Scientific reports 2017 Apr 11;7:46344
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- COLO 320 cells were subjected to SDS PAGE followed by western blot with 10997-2-AP( POLG2 Antibody) at dilution of 1:300
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 10997-2-AP( POLG2 Antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The POLG2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human POLG2. This antibody recognizes human,mouse,rat antigen. The POLG2 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
