Antibody data

Product number
BS8363
Provider
Bioworld Technology, Inc
Product name
POLG2 polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS8363
Antibody type
Polyclonal
Antigen
Recombinant full length Human POLG2.
Description
DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases. DNA pol ÎÛ2 (polymerase (DNA directed), gamma 2, accessory subunit), also known as mitochondrial DNA polymerase accessory subunit, POLB, HP55, PEOA4, POLGB, MTPOLB, POLG-BETA or POLG2, is a 485 amino acid subunit of mitochondrial DNA pol ÎÛ. DNA pol ÎÛ2 enhances DNA binding and promotes processive DNA synthesis. Defects in the gene encoding DNA pol ÎÛ2 are the cause of PEOA4 (progressive external ophthalmoplegia with mitochondrial DNA deletions autosomal dominant type 4).
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Provider Type Product Number
- No reagents -