Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [3]
- ELISA [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN396192 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Oculocerebrorenal Syndrome of Lowe (OCRL) (AA 146-240) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 146-240
- Isotype
- IgG
- Antibody clone number
- 4A6
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references OCRL1 function in renal epithelial membrane traffic.
Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1.
Development of a multiplex ligation-dependent probe amplification (MLPA) assay for quantification of the OCRL1 gene.
Locus heterogeneity of Dent's disease: OCRL1 and TMEM27 genes in patients with no CLCN5 mutations.
Lowe syndrome patient fibroblasts display Ocrl1-specific cell migration defects that cannot be rescued by the homologous Inpp5b phosphatase.
Cui S, Guerriero CJ, Szalinski CM, Kinlough CL, Hughey RP, Weisz OA
American journal of physiology. Renal physiology 2010 Feb;298(2):F335-45
American journal of physiology. Renal physiology 2010 Feb;298(2):F335-45
Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1.
Swan LE, Tomasini L, Pirruccello M, Lunardi J, De Camilli P
Proceedings of the National Academy of Sciences of the United States of America 2010 Feb 23;107(8):3511-6
Proceedings of the National Academy of Sciences of the United States of America 2010 Feb 23;107(8):3511-6
Development of a multiplex ligation-dependent probe amplification (MLPA) assay for quantification of the OCRL1 gene.
Coutton C, Monnier N, Rendu J, Lunardi J
Clinical biochemistry 2010 Apr;43(6):609-14
Clinical biochemistry 2010 Apr;43(6):609-14
Locus heterogeneity of Dent's disease: OCRL1 and TMEM27 genes in patients with no CLCN5 mutations.
Tosetto E, Addis M, Caridi G, Meloni C, Emma F, Vergine G, Stringini G, Papalia T, Barbano G, Ghiggeri GM, Ruggeri L, Miglietti N, D Angelo A, Melis MA, Anglani F
Pediatric nephrology (Berlin, Germany) 2009 Oct;24(10):1967-73
Pediatric nephrology (Berlin, Germany) 2009 Oct;24(10):1967-73
Lowe syndrome patient fibroblasts display Ocrl1-specific cell migration defects that cannot be rescued by the homologous Inpp5b phosphatase.
Coon BG, Mukherjee D, Hanna CB, Riese DJ 2nd, Lowe M, Aguilar RC
Human molecular genetics 2009 Dec 1;18(23):4478-91
Human molecular genetics 2009 Dec 1;18(23):4478-91
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
