FNab00322

antibody from FineTest Biotech
Targeting: ACTN1
Provider product page for FNab00322
Western blot
ELISA
Immunohistochemistry

Antibody data

Product number
FNab00322 - Provider product page
Provider
FineTest Biotech
Product name
alpha Actinin antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
Reactivity
Human, Mouse, Rat, Simian
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
actinin, alpha 1
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
ACTN1 protein structure - FNab00322 shown in red.