BS1410

LYN antibody from Bioworld Technology, Inc
JTK8
Western blot
Supportive data in Antibodypedia
Immunohistochemistry
Data presented on provider website

Antibody data

Product number
BS1410
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS1410, RRID:AB_1663388
Product name
Lyn (T501) polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS1410
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 461-510 of Human Lyn.
Description
Src is the human homolog of the v-Src gene of the Rous sarcoma virus, also known as avian sarcoma virus or ASV. Src is the first proto-oncogenic non-receptor tyrosine kinase characterized in human. By virtue of common structural motifs, the Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Src-family kinases transduce signals that are involved in the control of a variety of cellular processes, including proliferation, differentiation, motility and adhesion. Src-family kinases contain an amino-terminal cell membrane anchor followed by an SH3 domain and an SH2 domain involved in modular association and activation, respectively. Src-family kinases are normally maintained in an inactive state and can be activated transiently during cellular events such as mitosis. The human Lyn gene maps to chromosome 8q13 and encodes a 505 amino acid protein. Hematopoietic tissues predominantly express Lyn, which influences normal immunoglobulin production and regulation
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.