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- Antigen structure
- References [4]
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- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- ABIN500373 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Norrie Disease (Pseudoglioma) (NDP) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Norrin antibody was raised against an 18 amino acid peptide from near the amino terminus of human Norrin.
- Description
- Peptide affinity chromatography
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- N-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8°C for up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Ectopic norrin induces growth of ocular capillaries and restores normal retinal angiogenesis in Norrie disease mutant mice.
Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair.
Molecular modelling of the Norrie disease protein predicts a cystine knot growth factor tertiary structure.
Isolation of a candidate gene for Norrie disease by positional cloning.
Ohlmann A, Scholz M, Goldwich A, Chauhan BK, Hudl K, Ohlmann AV, Zrenner E, Berger W, Cvekl A, Seeliger MW, Tamm ER
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005 Feb 16;25(7):1701-10
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005 Feb 16;25(7):1701-10
Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair.
Xu Q, Wang Y, Dabdoub A, Smallwood PM, Williams J, Woods C, Kelley MW, Jiang L, Tasman W, Zhang K, Nathans J
Cell 2004 Mar 19;116(6):883-95
Cell 2004 Mar 19;116(6):883-95
Molecular modelling of the Norrie disease protein predicts a cystine knot growth factor tertiary structure.
Meitinger T, Meindl A, Bork P, Rost B, Sander C, Haasemann M, Murken J
Nature genetics 1993 Dec;5(4):376-80
Nature genetics 1993 Dec;5(4):376-80
Isolation of a candidate gene for Norrie disease by positional cloning.
Berger W, Meindl A, van de Pol TJ, Cremers FP, Ropers HH, Döerner C, Monaco A, Bergen AA, Lebo R, Warburg M
Nature genetics 1992 Jun;1(3):199-203
Nature genetics 1992 Jun;1(3):199-203
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of Norrin in Jurkat cell lysate with AP30608PU-N at (A) 1 and (B) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of Norrin in Jurkat cells with AP30608PU-N at 5 ?g/ml.
