Antibody data

Product number
BS8111
Provider
Bioworld Technology, Inc
Product name
NEU1 polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS8111
Antibody type
Polyclonal
Antigen
Recombinant full length Human NEU1.
Description
NEU1 encodes the lysosomal enzyme neuraminidase, Neu1, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids . In the lysosome Neu1 belongs to a heterotrimeric complex containing beta-galactosidase and cathepsin A (also referred to as 'protective protein') . In humans, primary or secondary deficiency of this enzyme leads to two clinically similar neurodegenerative lysosomal storage disorders: sialidosis and galactosialidosis (GS) . Sialidosis symptoms range from eye abnormalities and neurological disturbances to skeletal malformations, mental retardation and early death. Neu1 is expressed in the pancreas, muscle, kidney, placenta, heart, lung and liver. The human Neu1 gene maps to chromosome 6p21.33 and encodes a lysosomal protein localized on the inner side of the plasma membrane and in intracellular vesicles . Neu1 is also known as alpha-N-acetyl-neuraminidase and Acetylneuraminyl hydrolase .
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Provider Type Product Number
- No reagents -