TSHZ2

This gene is a member of the teashirt C2H2-type zinc-finger protein family of transcription factors. This gene encodes a protein with five C2H2-type zinc fingers, a homeobox DNA-binding domain and a coiled-coil domain. This nuclear protein is predicted to act as a transcriptional repressor. This gene is thought to play a role in the development and progression of breast and other types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]

Description

Teashirt zinc finger homeobox 2

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Golgi apparatus

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transcription factors

Chromosome

20 (52972358 - 53495330)

Ensembl ID

ENSG00000182463  (ver. 103.38)

Orthologs

Mouse Tshz2: ENSMUSG00000047907

UniProt

Q9NRE2

neXtProt

NX_Q9NRE2

Human splice variants
Mouse splice variants

Protein structure