Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [2]
- Immunocytochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- H00056339-B01P - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Polyclonal Methyltransferase like 3 Antibody
- Antibody type
- Polyclonal
- Description
- Protein A purified. NM_019852.3
- Reactivity
- Human, Mouse, Simian
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Modification of N6-methyladenosine RNA methylation on heat shock protein expression.
Synaptic N6-methyladenosine (m6A) epitranscriptome reveals functional partitioning of localized transcripts.
The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis.
Region-specific RNA m(6)A methylation represents a new layer of control in the gene regulatory network in the mouse brain.
A Unique ISR Program Determines Cellular Responses to Chronic Stress.
Dynamic m(6)A mRNA methylation directs translational control of heat shock response.
N6-methyladenosine marks primary microRNAs for processing.
Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase.
A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation.
Yu J, Li Y, Wang T, Zhong X
PloS one 2018;13(6):e0198604
PloS one 2018;13(6):e0198604
Synaptic N6-methyladenosine (m6A) epitranscriptome reveals functional partitioning of localized transcripts.
Merkurjev D, Hong WT, Iida K, Oomoto I, Goldie BJ, Yamaguti H, Ohara T, Kawaguchi SY, Hirano T, Martin KC, Pellegrini M, Wang DO
Nature neuroscience 2018 Jul;21(7):1004-1014
Nature neuroscience 2018 Jul;21(7):1004-1014
The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis.
Kobayashi M, Ohsugi M, Sasako T, Awazawa M, Umehara T, Iwane A, Kobayashi N, Okazaki Y, Kubota N, Suzuki R, Waki H, Horiuchi K, Hamakubo T, Kodama T, Aoe S, Tobe K, Kadowaki T, Ueki K
Molecular and cellular biology 2018 Aug 15;38(16)
Molecular and cellular biology 2018 Aug 15;38(16)
Region-specific RNA m(6)A methylation represents a new layer of control in the gene regulatory network in the mouse brain.
Chang M, Lv H, Zhang W, Ma C, He X, Zhao S, Zhang ZW, Zeng YX, Song S, Niu Y, Tong WM
Open biology 2017 Sep;7(9)
Open biology 2017 Sep;7(9)
A Unique ISR Program Determines Cellular Responses to Chronic Stress.
Guan BJ, van Hoef V, Jobava R, Elroy-Stein O, Valasek LS, Cargnello M, Gao XH, Krokowski D, Merrick WC, Kimball SR, Komar AA, Koromilas AE, Wynshaw-Boris A, Topisirovic I, Larsson O, Hatzoglou M
Molecular cell 2017 Dec 7;68(5):885-900.e6
Molecular cell 2017 Dec 7;68(5):885-900.e6
Dynamic m(6)A mRNA methylation directs translational control of heat shock response.
Zhou J, Wan J, Gao X, Zhang X, Jaffrey SR, Qian SB
Nature 2015 Oct 22;526(7574):591-4
Nature 2015 Oct 22;526(7574):591-4
N6-methyladenosine marks primary microRNAs for processing.
Alarcón CR, Lee H, Goodarzi H, Halberg N, Tavazoie SF
Nature 2015 Mar 26;519(7544):482-5
Nature 2015 Mar 26;519(7544):482-5
Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase.
Ping XL, Sun BF, Wang L, Xiao W, Yang X, Wang WJ, Adhikari S, Shi Y, Lv Y, Chen YS, Zhao X, Li A, Yang Y, Dahal U, Lou XM, Liu X, Huang J, Yuan WP, Zhu XF, Cheng T, Zhao YL, Wang X, Rendtlew Danielsen JM, Liu F, Yang YG
Cell research 2014 Feb;24(2):177-89
Cell research 2014 Feb;24(2):177-89
A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation.
Liu J, Yue Y, Han D, Wang X, Fu Y, Zhang L, Jia G, Yu M, Lu Z, Deng X, Dai Q, Chen W, He C
Nature chemical biology 2014 Feb;10(2):93-5
Nature chemical biology 2014 Feb;10(2):93-5
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Methyltransferase like 3 Antibody [H00056339-B01P] - Analysis of METTL3 expression in transfected 293T cell line by METTL3 polyclonal antibody. Lane 1: METTL3 transfected lysate(63.8 KDa). Lane 2: Non-transfected lysate.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Methyltransferase like 3 Antibody [H00056339-B01P] - Analysis of METTL3 expression in human colon.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunocytochemistry/Immunofluorescence: Methyltransferase like 3 Antibody [H00056339-B01P] - purified antibody to METTL3 on HeLa cell. [antibody concentration 10 ug/ml]
