Antibody data
- Antibody Data
- Antigen structure
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- Product number
- APR01794G - Provider product page
- Provider
- Leading Biology
- Product name
- FBXL15 Antibody - N-terminal region
- Antibody type
- Polyclonal
- Description
- Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Horse, Rabbit
- Host
- Rabbit
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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