FNab07940

antibody from FineTest Biotech

Targeting: SLC25A33 BMSC-MCP, MGC4399, PNC1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

FNab07940

Provider

FineTest Biotech

Product name

SLC25A33 antibody

Antibody type

Polyclonal

Antigen

Recombinant protein fragment

Description

Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria(PubMed:25320081). Transports preferentially uracil, thymine, and cytosine(deoxy)nucleoside di-and triphosphates by an antiport mechanism(PubMed:25320081). Also transports guanine but not adenine(deoxy)nucleotides(PubMed:25320081). Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials(mercury dichloride, mersalyl acid, p-hydroxymercuribenzoate)(PubMed:25320081). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration(PubMed:20453889). Upon INS or IGF1 stimulation regulates cell growth and proliferation by controlling mitochondrial DNA replication and transcription, the ratio of mitochondria-to nuclear-encoded components of the electron transport chain resulting in control of mitochondrial ROS production(PubMed:20453889, PubMed:17596519). Participates in dendritic cell endocytosis and may associate with mitochondrial oxidative phosphorylation(PubMed:14715278).

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

solute carrier family 25, member 33


Epitope

IgG

Isotype

IgG

Vial size

100¦Ìg

Concentration

Immunogen affinity purified

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

Handling

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)