BS2211

antibody from Bioworld Technology, Inc

Targeting: AHSA1 Aha1, C14orf3, hAha1, p38

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS2211

Provider

Bioworld Technology, Inc

Proper citation

Bioworld Technology Cat#BS2211, RRID:AB_1662709

Product name

AHA 1 (T183) polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide, corresponding to amino acids 151-200 of Human AHA-1.

Description

AHA-1 stimulates the inherent ATPase activity of yeast and human HSP 90 and interacts with the cytoplasmic tail of vesticular stomatitis virus glycoprotein. AHA-1 regulates HSP 90 by influencing the conformational state of the ¡ùATP lid¡ì and consequent N-terminal dimerization. It is crucial for cell viability under non-optimal growth conditions when HSP 90 levels are limiting. AHA-1 is a cytosolic protein and may transiently interact with the endoplasmic reticulum. It can have an affect on one step in the endoplasmic to Golgi trafficking. AHA-1 is expressed in numerous tissues, including brain, heart, skeletal muscle and kidney, and at lower levels in liver and placenta. It is induced by heat shock and treatment with the HSP 90 inhibitor 17-demethoxygeldanamycin.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.