Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 16768-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- GLT25D1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GLT25D1 antibody (Cat. #16768-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cyclophilin B control of lysine post-translational modifications of skin type I collagen.
Loss of function of Colgalt1 disrupts collagen post-translational modification and causes musculoskeletal defects.
Role of Glycosyltransferase 25 Domain 1 in Type I Collagen Glycosylation and Molecular Phenotypes.
Downregulation of Glt25d1 aggravates carbon tetrachloride‑induced acute hepatic injury through activation of the TGF‑β1/Smad2 signaling pathway.
Biallelic COLGALT1 variants are associated with cerebral small vessel disease.
Ascorbate starvation alters endoplasmic reticulum-resident enzymes in cardiac fibroblasts, priming them for increased procollagen secretion.
Terajima M, Taga Y, Cabral WA, Liu Y, Nagasawa M, Sumida N, Kayashima Y, Chandrasekaran P, Han L, Maeda N, Perdivara I, Hattori S, Marini JC, Yamauchi M
PLoS genetics 2019 Jun;15(6):e1008196
PLoS genetics 2019 Jun;15(6):e1008196
Loss of function of Colgalt1 disrupts collagen post-translational modification and causes musculoskeletal defects.
Geister KA, Lopez-Jimenez AJ, Houghtaling S, Ho TH, Vanacore R, Beier DR
Disease models & mechanisms 2019 Jun 17;12(6)
Disease models & mechanisms 2019 Jun 17;12(6)
Role of Glycosyltransferase 25 Domain 1 in Type I Collagen Glycosylation and Molecular Phenotypes.
Terajima M, Taga Y, Sricholpech M, Kayashima Y, Sumida N, Maeda N, Hattori S, Yamauchi M
Biochemistry 2019 Dec 17;58(50):5040-5051
Biochemistry 2019 Dec 17;58(50):5040-5051
Downregulation of Glt25d1 aggravates carbon tetrachloride‑induced acute hepatic injury through activation of the TGF‑β1/Smad2 signaling pathway.
Ye X, He L, Ma J, Li Y, Zhang M, Yang J, Zhang J, Xiao F, Wei H
Molecular medicine reports 2018 Oct;18(4):3611-3618
Molecular medicine reports 2018 Oct;18(4):3611-3618
Biallelic COLGALT1 variants are associated with cerebral small vessel disease.
Miyatake S, Schneeberger S, Koyama N, Yokochi K, Ohmura K, Shiina M, Mori H, Koshimizu E, Imagawa E, Uchiyama Y, Mitsuhashi S, Frith MC, Fujita A, Satoh M, Taguri M, Tomono Y, Takahashi K, Doi H, Takeuchi H, Nakashima M, Mizuguchi T, Takata A, Miyake N, Saitsu H, Tanaka F, Ogata K, Hennet T, Matsumoto N
Annals of neurology 2018 Dec;84(6):843-853
Annals of neurology 2018 Dec;84(6):843-853
Ascorbate starvation alters endoplasmic reticulum-resident enzymes in cardiac fibroblasts, priming them for increased procollagen secretion.
Cowling RT, Park JI, Sotimehin AE, Greenberg BH
Journal of molecular and cellular cardiology 2017 Dec;113:1-8
Journal of molecular and cellular cardiology 2017 Dec;113:1-8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GLT25D1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human GLT25D1. This antibody recognizes human,mouse,rat antigen. The GLT25D1 antibody has been validated for the following applications: ELISA, WB analysis.