Explore
Validate
Learn
Immunoprecipitation
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [3]
Submit
Validation data
Reference
Comment
Report error
- Product number
- MA5-28523 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- DUSP2 Monoclonal Antibody (PAC-1)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- The mouse monoclonal antibody PAC-1 recognizes an activation-induced conformational epitope PAC-1 on CD41/CD61 complex (gpIIb/IIIa), also known as integrin alpha IIb beta 3, a receptor which mediates platelet aggregation.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgM
- Antibody clone number
- PAC-1
- Vial size
- 100 µg
- Concentration
- 1 mg/mL
- Storage
- 4° C, do not freeze
Submitted references Rap1 and membrane lipids cooperatively recruit talin to trigger integrin activation.
Bromberger T, Zhu L, Klapproth S, Qin J, Moser M
Journal of cell science 2019 Nov 1;132(21)
Journal of cell science 2019 Nov 1;132(21)
No comments: Submit comment
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Flow cytometry multicolor staining pattern of human lymphocytes stained using anti-human CD41/CD61 (PAC-1) purified Monoclonal antibody (Product # MA5-28523), concentration in sample 8 µg/mL, GAM PE and Hoechst 34580.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Flow cytometry surface staining pattern of PHA stimulated human peripheral whole blood stained using anti-human CD41/CD61 (PAC-1) purified Monoclonal antibody (Product # MA5-28523), concentration in sample 8 µg/mL, GAM PE.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Separation of CD41/CD61 positive platelets (red-filled) from CD41/CD61 negative nucleated cells (black-dashed) in flow cytometry analysis (surface staining) of PHA stimulated human peripheral whole blood stained using anti-human CD41/CD61 (PAC-1) purified Monoclonal antibody (Product # MA5-28523), concentration in sample 8 µg/mL, GAM PE.
