Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- ELISA [1]
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Validation data
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- Product number
- H00025831-M03 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00025831-M03, RRID:AB_2117391
- Product name
- Mouse Monoclonal HECTD1 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. HECTD1 - HECT domain containing 1
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references The ubiquitin ligase HECTD1 promotes retinoic acid signaling required for development of the aortic arch.
HECTD1 controls the protein level of IQGAP1 to regulate the dynamics of adhesive structures.
Abnormal labyrinthine zone in the Hectd1-null placenta.
Hectd1 is required for development of the junctional zone of the placenta.
Hectd1 regulates intracellular localization and secretion of Hsp90 to control cellular behavior of the cranial mesenchyme.
Sugrue KF, Sarkar AA, Leatherbury L, Zohn IE
Disease models & mechanisms 2019 Jan 11;12(1)
Disease models & mechanisms 2019 Jan 11;12(1)
HECTD1 controls the protein level of IQGAP1 to regulate the dynamics of adhesive structures.
Shen X, Jia Z, D'Alonzo D, Wang X, Bruder E, Emch FH, De Geyter C, Zhang H
Cell communication and signaling : CCS 2017 Jan 5;15(1):2
Cell communication and signaling : CCS 2017 Jan 5;15(1):2
Abnormal labyrinthine zone in the Hectd1-null placenta.
Sarkar AA, Sabatino JA, Sugrue KF, Zohn IE
Placenta 2016 Feb;38:16-23
Placenta 2016 Feb;38:16-23
Hectd1 is required for development of the junctional zone of the placenta.
Sarkar AA, Nuwayhid SJ, Maynard T, Ghandchi F, Hill JT, Lamantia AS, Zohn IE
Developmental biology 2014 Aug 15;392(2):368-80
Developmental biology 2014 Aug 15;392(2):368-80
Hectd1 regulates intracellular localization and secretion of Hsp90 to control cellular behavior of the cranial mesenchyme.
Sarkar AA, Zohn IE
The Journal of cell biology 2012 Mar 19;196(6):789-800
The Journal of cell biology 2012 Mar 19;196(6):789-800
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- ELISA: HECTD1 Antibody (1E10) [H00025831-M03] - Detection limit for recombinant GST tagged HECTD1 is approximately 0.3ng/ml as a capture antibody.