Antibody data
- Antibody Data
- Antigen structure
- References [326]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 10094-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10094-1-AP, RRID:AB_2210695
- Product name
- beta Tubulin antibody
- Antibody type
- Polyclonal
- Description
- Beta Tubulin antibody (Cat. #10094-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 150ul
Submitted references Increased m6A-RNA methylation and FTO suppression is associated with myocardial inflammation and dysfunction during endotoxemia in mice.
Bioglass promotes wound healing by inhibiting endothelial cell pyroptosis through regulation of the connexin 43/reactive oxygen species (ROS) signaling pathway.
A homozygous loss-of-function mutation in FBXO43 causes human non-obstructive azoospermia.
An efficient strategy for digging protein-protein interactions for rational drug design - A case study with HIF-1α/VHL.
Sodium hydrosulfide reverses β2-microglobulin-induced depressive-like behaviors of male Sprague-Dawley rats: Involving improvement of synaptic plasticity and enhancement of Warburg effect in hippocampus.
Amelioration of scopolamine-induced learning and memory impairment by the TRPV4 inhibitor HC067047 in ICR mice.
The Regulatory Role of GBF1 on Osteoclast Activation Through EIF2a Mediated ER Stress and Novel Marker FAM129A Induction.
Tributyltin Oxide Exposure During in vitro Maturation Disrupts Oocyte Maturation and Subsequent Embryonic Developmental Competence in Pigs.
Iron Overload-Induced Ferroptosis Impairs Porcine Oocyte Maturation and Subsequent Embryonic Developmental Competence in vitro.
The m6A Reader YTHDF1 Facilitates the Tumorigenesis and Metastasis of Gastric Cancer via USP14 Translation in an m6A-Dependent Manner.
Expression and Functional Analysis of lncRNAs Involved in Platelet-Derived Growth Factor-BB-Induced Proliferation of Human Aortic Smooth Muscle Cells.
Transcriptome Differences in Pig Tracheal Epithelial Cells in Response to Pasteurella Multocida Infection.
USP37 downregulation elevates the Chemical Sensitivity of Human Breast Cancer Cells to Adriamycin.
MnSOD Lysine 68 acetylation leads to cisplatin and doxorubicin resistance due to aberrant mitochondrial metabolism.
Rosuvastatin Nanomicelles Target Neuroinflammation and Improve Neurological Deficit in a Mouse Model of Intracerebral Hemorrhage.
GluN2A/ERK/CREB Signaling Pathway Involved in Electroacupuncture Regulating Hypothalamic-Pituitary-Adrenal Axis Hyperactivity.
Latent Sex Differences in CaMKII-nNOS Signaling That Underlie Antidepressant-Like Effects of Yueju-Ganmaidazao Decoction in the Hippocampus.
PADI6 Regulates Trophoblast Cell Migration-Invasion Through the Hippo/YAP1 Pathway in Hydatidiform Moles.
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Loss of Diacylglycerol Kinase α Enhances Macrophage Responsiveness.
ZnT8 Deficiency Protects From APAP-Induced Acute Liver Injury by Reducing Oxidative Stress Through Upregulating Hepatic Zinc and Metallothioneins.
The Downregulation of eIF3a Contributes to Vemurafenib Resistance in Melanoma by Activating ERK via PPP2R1B.
CXCL5 Downregulation in Villous Tissue Is Correlated With Recurrent Spontaneous Abortion.
Protective Effect of Remdesivir Against Pulmonary Fibrosis in Mice.
Chlorogenic Acid Ameliorates Damage Induced by Fluorene-9-Bisphenol in Porcine Sertoli Cells.
Human umbilical cord-derived mesenchymal stem cell therapy ameliorates lupus through increasing CD4+ T cell senescence via MiR-199a-5p/Sirt1/p53 axis.
circCDYL2, Overexpressed in Highly Migratory Colorectal Cancer Cells, Promotes Migration by Binding to Ezrin.
The Role of KDM2B and EZH2 in Regulating the Stemness in Colorectal Cancer Through the PI3K/AKT Pathway.
Expression and prognostic potential of PLEK2 in head and neck squamous cell carcinoma based on bioinformatics analysis.
Supervillin Contributes to LPS-induced Inflammatory Response in THP-1 Cell-derived Macrophages.
Therapy of spinal cord injury by zinc modified gold nanoclusters via immune-suppressing strategies.
TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity.
Yixin-Fumai granules improve sick sinus syndrome in aging mice through Nrf-2/HO-1 pathway: A new target for sick sinus syndrome.
MicroRNA‑8063 targets heterogeneous nuclear ribonucleoprotein AB to inhibit the self‑renewal of colorectal cancer stem cells via the Wnt/β‑catenin pathway.
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
Cucurbit[7]uril as a Broad-Spectrum Antiviral Agent against Diverse RNA Viruses.
ZBP1-MLKL necroptotic signaling potentiates radiation-induced antitumor immunity via intratumoral STING pathway activation.
NORHA, a novel follicular atresia-related lncRNA, promotes porcine granulosa cell apoptosis via the miR-183-96-182 cluster and FoxO1 axis.
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Frugoside delays osteoarthritis progression via inhibiting miR-155-modulated synovial macrophage M1 polarization.
Naringin Promotes Skeletal Muscle Fiber Remodeling by the AdipoR1-APPL1-AMPK Signaling Pathway.
Arsenic trioxide induces expression of BCL-2 expression via NF-κB and p38 MAPK signaling pathways in BEAS-2B cells during apoptosis.
Reduced activity of intestinal surface Na+/H+ exchanger NHE3 is a key factor for induction of diarrhea after PEDV infection in neonatal piglets.
Tripartite motif-containing protein 16 protects against myocardial ischemia/reperfusion injury by affecting the Keap1/Nrf2 axis.
EGFR and ERK activation resists flavonoid quercetin-induced anticancer activities in human cervical cancer cells in vitro.
Guaiazulene derivative 1,2,3,4-tetrahydroazuleno[1,2-b] tropone reduces the production of ATP by inhibiting electron transfer complex II.
Vagus nerve stimulation mediates microglia M1/2 polarization via inhibition of TLR4 pathway after ischemic stroke.
Type IIB PKA is highly expressed in β cells and controls cell proliferation via regulating Cyclin D1 expression.
Golgi Phosphoprotein 3 Confers Radioresistance via Stabilizing EGFR in Lung Adenocarcinoma.
A network pharmacology approach to reveal the pharmacological targets and biological mechanism of compound kushen injection for treating pancreatic cancer based on WGCNA and in vitro experiment validation.
1,10-Seco-Eudesmane sesquiterpenoids as a new type of anti-neuroinflammatory agents by suppressing TLR4/NF-κB/MAPK pathways.
Iptakalim alleviates synaptic damages via targeting mitochondrial ATP-sensitive potassium channel in depression.
Characterization of ALTO-encoding circular RNAs expressed by Merkel cell polyomavirus and trichodysplasia spinulosa polyomavirus.
Plasma exosomes induce inflammatory immune response in patients with acute myocardial infarction.
Extracellular vesicles-based pre-targeting strategy enables multi-modal imaging of orthotopic colon cancer and image-guided surgery.
Functional domains and amino acid residues of Japanese eel IRF1, AjIRF1, regulate its nuclear import and IFN/Mx promoter activation.
Inhibition of ERAD synergizes with FTS to eradicate pancreatic cancer cells.
The combination of G-CSF and AMD3100 mobilizes bone marrow-derived stem cells to protect against cisplatin-induced acute kidney injury in mice.
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
lncRNA Ttc3-209 Promotes the Apoptosis of Retinal Ganglion Cells in Retinal Ischemia Reperfusion Injury by Targeting the miR-484/Wnt8a Axis.
Sesamin induces cell cycle arrest and apoptosis through p38/C-Jun N-terminal kinase mitogen-activated protein kinase pathways in human colorectal cancer cells.
Pharmacological effects of indole alkaloids from Alstonia scholaris (L.) R. Br. on pulmonary fibrosis in vivo.
Glycine alleviates fluoride-induced oxidative stress, apoptosis and senescence in a porcine testicular Sertoli cell line.
Alternative splicing transitions associate with emerging atrophy phenotype during denervation-induced skeletal muscle atrophy.
Melatonin ameliorates cypermethrin-induced impairments by regulating oxidative stress, DNA damage and apoptosis in porcine Sertoli cells.
Resolving the graft ischemia-reperfusion injury during liver transplantation at the single cell resolution.
Ameliorative effects of eosinophil deficiency on immune response, endoplasmic reticulum stress, apoptosis, and autophagy in fungus-induced allergic lung inflammation.
Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.
PI3K/AKT pathway mediates the antidepressant- and anxiolytic-like roles of hydrogen sulfide in streptozotocin-induced diabetic rats via promoting hippocampal neurogenesis.
AEG-1 Knockdown Sensitizes Glioma Cells to Radiation Through Impairing Homologous Recombination Via Targeting RFC5.
The role of SAMM50 in non-alcoholic fatty liver disease: from genetics to mechanisms.
Isoeucommin A attenuates kidney injury in diabetic nephropathy through the Nrf2/HO-1 pathway.
MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking.
The plant hormone abscisic acid stimulates megakaryocyte differentiation from human iPSCs in vitro.
Theaflavin Promotes Mitochondrial Abundance and Glucose Absorption in Myotubes by Activating the CaMKK2-AMPK Signal Axis via Calcium-Ion Influx.
Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model.
SMAD4 Inhibits Granulosa Cell Apoptosis via the miR-183-96-182 Cluster and FoxO1 Axis.
Attractin Gene Deficiency in Rats Leads to Impairments in Both Activity and Spatial Learning and Memory.
Betulinic acid attenuated bleomycin-induced pulmonary fibrosis by effectively intervening Wnt/β-catenin signaling.
ETV5 Regulates Hepatic Fatty Acid Metabolism Through PPAR Signaling Pathway.
Identification and Bioinformatic Assessment of circRNA Expression After RMI1 Knockdown and Ionizing Radiation Exposure.
NADPH levels affect cellular epigenetic state by inhibiting HDAC3-Ncor complex.
Libertellenone H, a Natural Pimarane Diterpenoid, Inhibits Thioredoxin System and Induces ROS-Mediated Apoptosis in Human Pancreatic Cancer Cells.
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy.
A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA.
Formaldehyde induces ferroptosis in hippocampal neuronal cells by upregulation of the Warburg effect.
CHIP protects against MPP+/MPTP-induced damage by regulating Drp1 in two models of Parkinson's disease.
BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.
Oral Administration of Probiotic Bifidobacterium breve Improves Facilitation of Hippocampal Memory Extinction via Restoration of Aberrant Higher Induction of Neuropsin in an MPTP-Induced Mouse Model of Parkinson's Disease.
A novel tonicity-responsive microRNA miR-23a-5p modulates renal cell survival under osmotic stress through targeting heat shock protein 70 HSPA1B.
Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology.
Integrated Metabolomics and Transcriptomics Analyses Reveal Metabolic Landscape in Neuronal Cells during JEV Infection.
Decreased NHE3 activity in intestinal epithelial cells in TGEV and PEDV-induced piglet diarrhea.
The STING antagonist H-151 ameliorates psoriasis via suppression of STING/NF-κB-mediated inflammation.
Mbd2 deficiency alleviates retinal cell apoptosisvia the miR-345-5p/Atf1 axis in high glucoseinjury and streptozotocin-induced diabetic mice.
TRPV4 inhibitor HC067047 produces antidepressant-like effect in LPS-induced depression mouse model.
Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.
NOD2 deficiency confers a pro-tumorigenic macrophage phenotype to promote lung adenocarcinoma progression.
Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Ameliorate HaCaT Cell Photo-Aging.
TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis.
The E2F1/USP11 positive feedback loop promotes hepatocellular carcinoma metastasis and inhibits autophagy by activating ERK/mTOR pathway.
High-Carbohydrate Diet Alleviates the Oxidative Stress, Inflammation and Apoptosis of Megalobrama amblycephala Following Dietary Exposure to Silver Nanoparticles.
Triptolide impairs glycolysis by suppressing GATA4/Sp1/PFKP signaling axis in mouse Sertoli cells.
KPNB1-mediated nuclear translocation of PD-L1 promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signaling pathway.
HSP/HSC70 activity is required for Bombyx mori nucleopolyhedrovirus replication at the early infectious phase.
Salidroside Attenuates Doxorubicin-Induced Cardiac Dysfunction Partially Through Activation of QKI/FoxO1 Pathway.
Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1.
Neural Tube Defects and ZIC4 Hypomethylation in Relation to Polycyclic Aromatic Hydrocarbon Exposure.
Identification of Transcriptional Variation in Aortic Remodeling Using a Murine Transverse Aortic Constriction (TAC) Model.
Similar Repair Effects of Human Placenta, Bone Marrow Mesenchymal Stem Cells, and Their Exosomes for Damaged SVOG Ovarian Granulosa Cells.
Beneficial Effects of Crocin against Depression via Pituitary Adenylate Cyclase-Activating Polypeptide.
Anti-Inflammatory and Antioxidant Effect of Eucommia ulmoides Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-κB Pathway.
Skp2 modulates proliferation, senescence and tumorigenesis of glioma.
HCK can serve as novel prognostic biomarker and therapeutic target for Breast Cancer patients.
Repression of FGF signaling is responsible for Dnmt3b inhibition and impaired de novo DNA methylation during early development of in vitro fertilized embryos.
G Protein-Coupled Receptor 109A Maintains the Intestinal Integrity and Protects Against ETEC Mucosal Infection by Promoting IgA Secretion.
Integration of Transcriptomics and Metabolomics Reveals the Antitumor Mechanism Underlying Shikonin in Colon Cancer.
Possible Roles of Proinflammatory Signaling in Keratinocytes Through Aryl Hydrocarbon Receptor Ligands for the Development of Squamous Cell Carcinoma.
Control the fate of human umbilical cord mesenchymal stem cells with dual-enzymatically cross-linked gelatin hydrogels for potential applications in nerve regeneration.
miR-361-5p Mediates SMAD4 to Promote Porcine Granulosa Cell Apoptosis through VEGFA.
Neddylation promotes protein translocation between the cytoplasm and nucleus.
EPS8 regulates an NLRP3 inflammasome-independent caspase-1 activation pathway in monosodium urate crystal-treated RAW264.7 macrophages.
RNA-binding protein CUGBP1 controls the differential INSR splicing in molecular subtypes of breast cancer cells and affects cell aggressiveness.
Chrysin Inhibits Melanoma Tumor Metastasis via Interfering with the FOXM1/β-Catenin Signaling.
Indole alkaloids from leaves of Alstonia scholaris (L.) R. Br. protect against emphysema in mice.
miR-203 inhibits cell proliferation and ERK pathway in prostate cancer by targeting IRS-1.
Identification of long-term survival-associated gene in breast cancer.
bta-miR-23a Regulates the Myogenic Differentiation of Fetal Bovine Skeletal Muscle-Derived Progenitor Cells by Targeting MDFIC Gene.
Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage.
Efficacy of a wound-dressing biomaterial on prevention of postinflammatory hyperpigmentation after suction blister epidermal grafting in stable vitiligo patients: a controlled assessor-blinded clinical study with in vitro bioactivity investigation.
The critical role of the hippocampal NLRP3 inflammasome in social isolation-induced cognitive impairment in male mice.
MitoQ attenuates brain damage by polarizing microglia towards the M2 phenotype through inhibition of the NLRP3 inflammasome after ICH.
The B7-H4 gene induces immune escape partly via upregulating the PD-1/Stat3 pathway in non-small cell lung cancer.
Protein target identification of ginsenosides in skeletal muscle tissues: discovery of natural small-molecule activators of muscle-type creatine kinase.
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Leptin mediates protection of hydrogen sulfide against 6-hydroxydopamine-induced Parkinson's disease: Involving enhancement in Warburg effect.
Neuropeptide Y1 receptor antagonist promotes osteoporosis and microdamage repair and enhances osteogenic differentiation of bone marrow stem cells via cAMP/PKA/CREB pathway.
A Novel Mechanism of bta-miR-210 in Bovine Early Intramuscular Adipogenesis.
Crosstalk between androgen and Wnt/β-catenin leads to changes of wool density in FGF5-knockout sheep.
Synergistic antifibrotic effects of miR-451 with miR-185 partly by co-targeting EphB2 on hepatic stellate cells.
Synthesis and biological evaluations of N'-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents.
Mbd2 Mediates Retinal Cell Apoptosis by Targeting the lncRNA Mbd2-AL1/miR-188-3p/Traf3 Axis in Ischemia/Reperfusion Injury.
Anti-neuroinflammatory effect of 3,4-dihydroxybenzaldehyde in ischemic stroke.
Yueju-Ganmaidazao Decoction confers rapid antidepressant-like effects and the involvement of suppression of NMDA/NO/cGMP signaling.
The developmental and experience-dependent expression of IGF-2 in mice visual cortex.
Overexpression of NRF1-742 or NRF1-772 Reduces Arsenic-Induced Cytotoxicity and Apoptosis in Human HaCaT Keratinocytes.
Circular RNA hsa_circ_0008285 inhibits colorectal cancer cell proliferation and migration via the miR-382-5p/PTEN axis.
Hepatic HuR modulates lipid homeostasis in response to high-fat diet.
Melatonin regulates mitochondrial dynamics and alleviates neuron damage in prion diseases.
PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition.
A novel microRNA and its pfk target control growth length in the freshwater shrimp Neocaridina heteropoda.
Cortistatin ameliorates Ang II-induced proliferation of vascular smooth muscle cells by inhibiting autophagy through SSTR3 and SSTR5.
Nucleus-located PDK1 regulates growth, invasion and migration of breast cancer cells.
Autophagy inducer activates Nrf2-ARE pathway to attenuate aberrant alveolarization in neonatal rats with bronchopulmonary dysplasia.
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis.
SSEA3 and Sialyl Lewis a Glycan Expression Is Controlled by B3GALT5 LTR through Lamin A-NFYA and SIRT1-STAT3 Signaling in Human ES Cells.
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA2 phosphorylation in experimental ischemic stroke.
Pizotifen inhibits the proliferation and invasion of gastric cancer cells.
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABAA receptors.
Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma.
NCAPG Dynamically Coordinates the Myogenesis of Fetal Bovine Tissue by Adjusting Chromatin Accessibility.
Sodium butyrate causes α-synuclein degradation by an Atg5-dependent and PI3K/Akt/mTOR-related autophagy pathway.
Oxidative stress-mediated hepatotoxicity in rats induced by ethanol extracts of different parts of Chloranthus serratus.
Regulation of indoleamine 2, 3-dioxygenase in hippocampal microglia by NLRP3 inflammasome in lipopolysaccharide-induced depressive-like behaviors.
Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.
IGFBP6 regulates vascular smooth muscle cell proliferation and morphology via cyclin E-CDK2.
Inhibition of p38 MAPK regulates epileptic severity by decreasing expression levels of A1R and ENT1.
Tongmai formula improves cardiac function via regulating mitochondrial quality control in the myocardium with ischemia/reperfusion injury.
Radiosensitization Effect of AGuIX, a Gadolinium-Based Nanoparticle, in Nonsmall Cell Lung Cancer.
Adiponectin protects HL-1 cardiomyocytes against rotenone-induced cytotoxicity through AMPK activation.
Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer.
Blood coagulation factor VIII D1241E polymorphism leads to a weak malectin interaction and reduction of factor VIII posttranslational modification and secretion.
Homocysteine downregulates cardiac homeobox transcription factor NKX2.5 via IGFBP5.
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Interplay of m6A and H3K27 trimethylation restrains inflammation during bacterial infection.
WWP2 regulates SIRT1-STAT3 acetylation and phosphorylation involved in hypertensive angiopathy.
Myricetin ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting TGF-β signaling via targeting HSP90β.
Lnc-M2 controls M2 macrophage differentiation via the PKA/CREB pathway.
Anti-Inflammatory Effect of Simonsinol on Lipopolysaccharide Stimulated RAW264.7 Cells through Inactivation of NF-κB Signaling Pathway.
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes.
Design, synthesis and biological evaluation of a novel tubulin inhibitor SKLB0565 targeting the colchicine binding site.
The E3 ubiquitin ligase Smurf2 regulates PARP1 stability to alleviate oxidative stress-induced injury in human umbilical vein endothelial cells.
Monophosphoryl lipid A alleviated radiation-induced testicular injury through TLR4-dependent exosomes.
Inhibition of histone acetyltransferase GCN5 extends lifespan in both yeast and human cell lines.
The ubiquitin-specific protease USP8 directly deubiquitinates SQSTM1/p62 to suppress its autophagic activity.
Exogenous H2S Induces Hrd1 S-sulfhydration and Prevents CD36 Translocation via VAMP3 Ubiquitylation in Diabetic Hearts.
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
BH3 mimetic ABT-263 enhances the anticancer effects of apigenin in tumor cells with activating EGFR mutation.
The Binding of PD-L1 and Akt Facilitates Glioma Cell Invasion Upon Starvation via Akt/Autophagy/F-Actin Signaling.
Neuroprotective Effect of Echinacoside in Subacute Mouse Model of Parkinson's Disease.
Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1).
(-)-Epigallocatechin-3-gallate derivatives combined with cisplatin exhibit synergistic inhibitory effects on non-small-cell lung cancer cells.
Long-Term Effects of Zinc Deficiency and Zinc Supplementation on Developmental Seizure-Induced Brain Damage and the Underlying GPR39/ZnT-3 and MBP Expression in the Hippocampus.
Catalpol prevents denervated muscular atrophy related to the inhibition of autophagy and reduces BAX/BCL2 ratio via mTOR pathway.
Lipoxin A4 Regulates Lipopolysaccharide-Induced BV2 Microglial Activation and Differentiation via the Notch Signaling Pathway.
Protein kinase C-iota-mediated glycolysis promotes non-small-cell lung cancer progression.
LXRα Promotes the Differentiation of Human Gastric Cancer Cells through Inactivation of Wnt/β-catenin Signaling.
A Comparative Peptidomic Characterization of Cultured Skeletal Muscle Tissues Derived From db/db Mice.
TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease.
An improved Tet-on system in microRNA overexpression and CRISPR/Cas9-mediated gene editing.
Anti-TGEV Miller Strain Infection Effect of Lactobacillus plantarum Supernatant Based on the JAK-STAT1 Signaling Pathway.
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
Integrating yeast chemical genomics and mammalian cell pathway analysis.
Sorafenib kills liver cancer cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids via the ATP-AMPK-mTOR-SREBP1 signaling pathway.
The oncogenic role of CB2 in the progression of non-small-cell lung cancer.
Exosomal transfer of miR-501 confers doxorubicin resistance and tumorigenesis via targeting of BLID in gastric cancer.
USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway.
Deregulated lncRNA expression profile in the mouse lung adenocarcinomas with KRAS-G12D mutation and P53 knockout.
Developmental nicotine exposure elicits multigenerational disequilibria in proBDNF proteolysis and glucocorticoid signaling in the frontal cortices, striata, and hippocampi of adolescent mice.
Oxidation derivative of (-)-epigallocatechin-3-gallate (EGCG) inhibits RANKL-induced osteoclastogenesis by suppressing RANK signaling pathways in RAW 264.7 cells.
HIF-1α contributes to Ang II-induced inflammatory cytokine production in podocytes.
The CRISPR-Cas13a Gene-Editing System Induces Collateral Cleavage of RNA in Glioma Cells.
An LTR retrotransposon-derived lncRNA interacts with RNF169 to promote homologous recombination.
Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury.
Astaxanthin inhibits proliferation and induces apoptosis of LX‑2 cells by regulating the miR‑29b/Bcl‑2 pathway.
Sirt2 epigenetically down-regulates PDGFRα expression and promotes CG4 cell differentiation.
Casp8 hypomethylation and neural tube defects in association with polycyclic aromatic hydrocarbon exposure.
The protective effects of XH-105 against radiation-induced intestinal injury.
Leonurine promotes neurite outgrowth and neurotrophic activity by modulating the GR/SGK1 signaling pathway in cultured PC12 cells.
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Long noncoding RNA CCAT2 promotes hepatocellular carcinoma proliferation and metastasis through up-regulation of NDRG1.
Role of Nkx2.5 in H(2)O(2)-induced Nsd1 suppression.
Long-term pulmonary exposure to multi-walled carbon nanotubes promotes breast cancer metastatic cascades.
Aloperine suppresses human pulmonary vascular smooth muscle cell proliferation via inhibiting inflammatory response.
PMP22 Regulates Cholesterol Trafficking and ABCA1-Mediated Cholesterol Efflux.
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats.
YAP mediates the positive regulation of hnRNPK on the lung adenocarcinoma H1299 cell growth.
Involvement of the microglial NLRP3 inflammasome in the anti-inflammatory effect of the antidepressant clomipramine.
S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA2 phosphorylation.
Matrix Metalloproteases-Mediated Cleavage on β-Dystroglycan May Play a Key Role in the Blood-Brain Barrier After Intracerebral Hemorrhage in Rats.
Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells.
KIAA1199 promotes metastasis of colorectal cancer cells via microtubule destabilization regulated by a PP2A/stathmin pathway.
Echinacoside protects against MPTP/MPP+-induced neurotoxicity via regulating autophagy pathway mediated by Sirt1.
Activation of brain endothelium by Escherichia coli K1 virulence factor cglD promotes polymorphonuclear leukocyte transendothelial migration.
Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates.
Structural and functional damage to the hippocampal neurovascular unit in diabetes-related depression.
Exosomes from human adipose-derived stem cells promote sciatic nerve regeneration via optimizing Schwann cell function.
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Water-separated part of Chloranthus serratus alleviates lipopolysaccharide- induced RAW264.7 cell injury mainly by regulating the MAPK and Nrf2/HO-1 inflammatory pathways.
Hypoxic postconditioning activates the Wnt/β-catenin pathway and protects against transient global cerebral ischemia through Dkk1 Inhibition and GSK-3β inactivation.
Inhibition of dendritic spine extension through acrolein conjugation with α-, β-tubulin proteins.
Crocin induces anti-ischemia in middle cerebral artery occlusion rats and inhibits autophagy by regulating the mammalian target of rapamycin.
RMI1 contributes to DNA repair and to the tolerance to camptothecin.
EIF4A2 interacts with the membrane protein of transmissible gastroenteritis coronavirus and plays a role in virus replication.
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
NKX2-2 Suppresses Osteosarcoma Metastasis and Proliferation by Downregulating Multiple Target Genes.
Caffeine Promotes Conversion of Palmitic Acid to Palmitoleic Acid by Inducing Expression of fat-5 in Caenorhabditis elegans and scd1 in Mice.
EGFR as a Negative Regulatory Protein Adjusts the Activity and Mobility of NHE3 in the Cell Membrane of IPEC-J2 Cells With TGEV Infection.
Involvement of NMDA-AKT-mTOR Signaling in Rapid Antidepressant-Like Activity of Chaihu-jia-Longgu-Muli-tang on Olfactory Bulbectomized Mice.
Effect of Black Tea Extract and Thearubigins on Osteoporosis in Rats and Osteoclast Formation in vitro.
Phosphorylation of IRS4 by CK1γ2 promotes its degradation by CHIP through the ubiquitin/lysosome pathway.
Effect of decabrominated diphenyl ether exposure on spatial learning and memory, the expression and phosphorylation of hippocampal glutamate receptor subunits in adult Sprague-Dawley rats.
iTRAQ-Based Proteomics Analysis Reveals the Effect of Rhubarb in Rats with Ischemic Stroke.
The Protective Effect of New Compound XH-103 on Radiation-Induced GI Syndrome.
PAX2 may induce ADAM10 expression in renal tubular epithelial cells and contribute to epithelial-to-mesenchymal transition.
Rapid induction of apoptosis in tumor cells treated with a new platinum(II) complex based on amino-thiazolidinone.
Theabrownin suppresses in vitro osteoclastogenesis and prevents bone loss in ovariectomized rats.
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Apolipoprotein E deficiency accelerates atherosclerosis development in miniature pigs.
Temporal Proteomic Analysis of Pancreatic β-Cells in Response to Lipotoxicity and Glucolipotoxicity.
Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells.
Horizontal transfer of exosomal CXCR4 promotes murine hepatocarcinoma cell migration, invasion and lymphangiogenesis.
KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.
The ubiquitin-specific protease USP8 deubiquitinates and stabilizes Cx43.
PMN inhibits colorectal cancer cells through inducing mitotic arrest and p53-dependent apoptosis via the inhibition of tubulin polymerization.
Met is involved in TIGAR-regulated metastasis of non-small-cell lung cancer.
Combined treatment with Dendrobium candidum and black tea extract promotes osteoprotective activity in ovariectomized estrogen deficient rats and osteoclast formation.
CCAAT/enhancer-binding protein β overexpression alleviates myocardial remodelling by regulating angiotensin-converting enzyme-2 expression in diabetes.
PTEN-L promotes type I interferon responses and antiviral immunity.
Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex.
Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production.
Synergistic neuroprotective effect of rasagiline and idebenone against retinal ischemia-reperfusion injury via the Lin28-let-7-Dicer pathway.
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
The antidepressant effects of ɑ-tocopherol are related to activation of autophagy via the AMPK/mTOR pathway.
Pu-erh Tea Extract Ameliorates Ovariectomy-Induced Osteoporosis in Rats and Suppresses Osteoclastogenesis In Vitro.
Role of the Ubiquitin C-Terminal Hydrolase L1-Modulated Ubiquitin Proteasome System in Auditory Cortex Senescence.
Neural Plasticity Associated with Hippocampal PKA-CREB and NMDA Signaling Is Involved in the Antidepressant Effect of Repeated Low Dose of Yueju Pill on Chronic Mouse Model of Learned Helplessness.
Tail Nerve Electrical Stimulation and Electro-Acupuncture Can Protect Spinal Motor Neurons and Alleviate Muscle Atrophy after Spinal Cord Transection in Rats.
Regulatory Axis of miR-195/497 and HMGA1-Id3 Governs Muscle Cell Proliferation and Differentiation.
2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid, a glutathione reductase inhibitor, induces G2/M cell cycle arrest through generation of thiol oxidative stress in human esophageal cancer cells.
Nrf2 Promotes Keratinocyte Proliferation in Psoriasis through Up-Regulation of Keratin 6, Keratin 16, and Keratin 17.
Synthesis of β-tubulin occurs within chromatoid body of round spermatids.
PRAS40 alleviates neurotoxic prion peptide-induced apoptosis via mTOR-AKT signaling.
High expression of ubiquitin-specific peptidase 39 is associated with the development of vascular remodeling.
Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages.
MicroRNA-17-92 Regulates the Transcription Factor E2F3b during Myogenesis In Vitro and In Vivo.
CBX3 promotes colon cancer cell proliferation by CDK6 kinase-independent function during cell cycle.
cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases.
ERK1/2-mediated Cytoplasmic Accumulation of hnRNPK Antagonizes TRAIL-induced Apoptosis through Upregulation of XIAP in H1299 Cells.
Abl2 kinase phosphorylates Bi-organellar regulator MNRR1 in mitochondria, stimulating respiration.
miR-34b Modulates Skeletal Muscle Cell Proliferation and Differentiation.
Alginate enhances Toll-like receptor 4-mediated phagocytosis by murine RAW264.7 macrophages.
Knockdown of RMI1 impairs DNA repair under DNA replication stress.
Overexpression of DBC1, correlated with poor prognosis, is a potential therapeutic target for hepatocellular carcinoma.
LL-37-induced human mast cell activation through G protein-coupled receptor MrgX2.
The mechanically activated p38/MMP-2 signaling pathway promotes bone marrow mesenchymal stem cell migration in rats.
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
The DEAD-Box RNA Helicase DDX3 Interacts with NF-κB Subunit p65 and Suppresses p65-Mediated Transcription.
Six2 Is a Coordinator of LiCl-Induced Cell Proliferation and Apoptosis.
MicroRNA-378 Alleviates Cerebral Ischemic Injury by Negatively Regulating Apoptosis Executioner Caspase-3.
Up-regulation of miR-95-3p in hepatocellular carcinoma promotes tumorigenesis by targeting p21 expression.
Senkyunolide I attenuates oxygen-glucose deprivation/reoxygenation-induced inflammation in microglial cells.
Conventional protein kinase Cβ-mediated phosphorylation inhibits collapsin response-mediated protein 2 proteolysis and alleviates ischemic injury in cultured cortical neurons and ischemic stroke-induced mice.
The tumor suppressor PTEN has a critical role in antiviral innate immunity.
Hen egg white ovomacroglobulin promotes fibroblast migration via mediating cell adhesion and cytoskeleton.
Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.
Tubb3 regulation by the Erk and Akt signaling pathways: a mechanism involved in the effect of arginine ADP-ribosyltransferase 1 (Art1) on apoptosis of colon carcinoma CT26 cells.
Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers.
Inhibition of autophagy by 3-MA enhances IL-24-induced apoptosis in human oral squamous cell carcinoma cells.
Expression of Iodotyrosine Deiodinase in Thyroid and Other Organs in Iodine-Deficient and Iodine-Excess Rats.
Regulation of signal transducer and activator of transcription 3 and apoptotic pathways by betaine attenuates isoproterenol-induced acute myocardial injury in rats.
SCD1 negatively regulates autophagy-induced cell death in human hepatocellular carcinoma through inactivation of the AMPK signaling pathway.
Expression and localization of estrogen receptor in human breast cancer and its clinical significance.
Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo.
Quantitative proteomic study of myocardial mitochondria in urea transporter B knockout mice.
The mechanisms of EGFR in the regulation of axon regeneration.
CXXC5 Associates with Smads to Mediate TNF-α Induced Apoptosis.
Downregulation of miR-181b in mouse brain following ischemic stroke induces neuroprotection against ischemic injury through targeting heat shock protein A5 and ubiquitin carboxyl-terminal hydrolase isozyme L1.
Modulation of calcineurin activity in mouse brain by chronic oral administration of cyclosporine A.
Effect of pioglitazone on altered expression of Aβ metabolism-associated molecules in the brain of fructose-drinking rats, a rodent model of insulin resistance.
Mutational analysis of ErbB2 intracellular localization.
Dubey PK, Patil M, Singh S, Dubey S, Ahuja P, Verma SK, Krishnamurthy P
Molecular and cellular biochemistry 2022 Jan;477(1):129-141
Molecular and cellular biochemistry 2022 Jan;477(1):129-141
Bioglass promotes wound healing by inhibiting endothelial cell pyroptosis through regulation of the connexin 43/reactive oxygen species (ROS) signaling pathway.
Zhang K, Chai B, Ji H, Chen L, Ma Y, Zhu L, Xu J, Wu Y, Lan Y, Li H, Feng Z, Xiao J, Zhang H, Xu K
Laboratory investigation; a journal of technical methods and pathology 2022 Jan;102(1):90-101
Laboratory investigation; a journal of technical methods and pathology 2022 Jan;102(1):90-101
A homozygous loss-of-function mutation in FBXO43 causes human non-obstructive azoospermia.
Wu H, Zhang X, Shen Q, Liu Y, Gao Y, Wang G, Lv M, Hua R, Xu Y, Zhou P, Wei Z, Tao F, He X, Cao Y, Liu M
Clinical genetics 2022 Jan;101(1):55-64
Clinical genetics 2022 Jan;101(1):55-64
An efficient strategy for digging protein-protein interactions for rational drug design - A case study with HIF-1α/VHL.
Xue X, Kang JB, Yang X, Li N, Chang L, Ji J, Meng XK, Zhang HQ, Zhong Y, Yu SP, Wu WY, Wang XL, Li NG, Sun SL
European journal of medicinal chemistry 2022 Jan 5;227:113871
European journal of medicinal chemistry 2022 Jan 5;227:113871
Sodium hydrosulfide reverses β2-microglobulin-induced depressive-like behaviors of male Sprague-Dawley rats: Involving improvement of synaptic plasticity and enhancement of Warburg effect in hippocampus.
Yang SQ, Tang YY, Zeng D, Tian Q, Wei HJ, Wang CY, Zhang P, Chen YJ, Zou W, Tang XQ
Behavioural brain research 2022 Jan 24;417:113562
Behavioural brain research 2022 Jan 24;417:113562
Amelioration of scopolamine-induced learning and memory impairment by the TRPV4 inhibitor HC067047 in ICR mice.
Deng Y, Li W, Niu L, Luo X, Li J, Zhang Y, Liu H, He J, Wan W
Neuroscience letters 2022 Jan 10;767:136209
Neuroscience letters 2022 Jan 10;767:136209
The Regulatory Role of GBF1 on Osteoclast Activation Through EIF2a Mediated ER Stress and Novel Marker FAM129A Induction.
Wen C, Zhou Y, Xu Y, Tan H, Pang C, Liu H, Liu K, Wei L, Luo H, Qin T, He C, Liu C, Zhou C
Frontiers in cell and developmental biology 2021;9:706768
Frontiers in cell and developmental biology 2021;9:706768
Tributyltin Oxide Exposure During in vitro Maturation Disrupts Oocyte Maturation and Subsequent Embryonic Developmental Competence in Pigs.
Xiao Y, Yuan B, Hu W, Qi J, Jiang H, Sun B, Zhang J, Liang S
Frontiers in cell and developmental biology 2021;9:683448
Frontiers in cell and developmental biology 2021;9:683448
Iron Overload-Induced Ferroptosis Impairs Porcine Oocyte Maturation and Subsequent Embryonic Developmental Competence in vitro.
Hu W, Zhang Y, Wang D, Yang T, Qi J, Zhang Y, Jiang H, Zhang J, Sun B, Liang S
Frontiers in cell and developmental biology 2021;9:673291
Frontiers in cell and developmental biology 2021;9:673291
The m6A Reader YTHDF1 Facilitates the Tumorigenesis and Metastasis of Gastric Cancer via USP14 Translation in an m6A-Dependent Manner.
Chen XY, Liang R, Yi YC, Fan HN, Chen M, Zhang J, Zhu JS
Frontiers in cell and developmental biology 2021;9:647702
Frontiers in cell and developmental biology 2021;9:647702
Expression and Functional Analysis of lncRNAs Involved in Platelet-Derived Growth Factor-BB-Induced Proliferation of Human Aortic Smooth Muscle Cells.
Lin JJ, Chen W, Gong M, Xu X, Du MY, Wang SF, Yang LY, Wang Y, Liu KX, Kong P, Li B, Liu K, Li YM, Dong LH, Sun SG
Frontiers in cardiovascular medicine 2021;8:702718
Frontiers in cardiovascular medicine 2021;8:702718
Transcriptome Differences in Pig Tracheal Epithelial Cells in Response to Pasteurella Multocida Infection.
Wang X, Wang F, Lin L, Liang W, Liu S, Hua L, Wang X, Chen H, Peng Z, Wu B
Frontiers in veterinary science 2021;8:682514
Frontiers in veterinary science 2021;8:682514
USP37 downregulation elevates the Chemical Sensitivity of Human Breast Cancer Cells to Adriamycin.
Qin T, Cui XY, Xiu H, Huang C, Sun ZN, Xu XM, Li LH, Yue L
International journal of medical sciences 2021;18(2):325-334
International journal of medical sciences 2021;18(2):325-334
MnSOD Lysine 68 acetylation leads to cisplatin and doxorubicin resistance due to aberrant mitochondrial metabolism.
Gao Y, Zhu Y, Tran EL, Tokars V, Dean AE, Quan S, Gius D
International journal of biological sciences 2021;17(5):1203-1216
International journal of biological sciences 2021;17(5):1203-1216
Rosuvastatin Nanomicelles Target Neuroinflammation and Improve Neurological Deficit in a Mouse Model of Intracerebral Hemorrhage.
Zi L, Zhou W, Xu J, Li J, Li N, Xu J, You C, Wang C, Tian M
International journal of nanomedicine 2021;16:2933-2947
International journal of nanomedicine 2021;16:2933-2947
GluN2A/ERK/CREB Signaling Pathway Involved in Electroacupuncture Regulating Hypothalamic-Pituitary-Adrenal Axis Hyperactivity.
Wang Y, Han J, Zhu J, Zhang M, Ju M, Du Y, Tian Z
Frontiers in neuroscience 2021;15:703044
Frontiers in neuroscience 2021;15:703044
Latent Sex Differences in CaMKII-nNOS Signaling That Underlie Antidepressant-Like Effects of Yueju-Ganmaidazao Decoction in the Hippocampus.
Yin Y, Qian S, Chen Y, Sun Y, Li Y, Yu Y, Li J, Wu Z, Yu X, Ge R, Han J, Sun D, Wu H, Liu L, Xue W, Wang W
Frontiers in behavioral neuroscience 2021;15:640258
Frontiers in behavioral neuroscience 2021;15:640258
PADI6 Regulates Trophoblast Cell Migration-Invasion Through the Hippo/YAP1 Pathway in Hydatidiform Moles.
Huang B, Zhao Y, Zhou L, Gong T, Feng J, Han P, Qian J
Journal of inflammation research 2021;14:3489-3500
Journal of inflammation research 2021;14:3489-3500
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Cai C, Hu W, Zhang Y, Hu X, Yang S, Qiu H, Wang R, Ma M, Qiu Y, Chu T
Frontiers in pharmacology 2021;12:772540
Frontiers in pharmacology 2021;12:772540
Loss of Diacylglycerol Kinase α Enhances Macrophage Responsiveness.
Manigat LC, Granade ME, Taori S, Miller CA, Vass LR, Zhong XP, Harris TE, Purow BW
Frontiers in immunology 2021;12:722469
Frontiers in immunology 2021;12:722469
ZnT8 Deficiency Protects From APAP-Induced Acute Liver Injury by Reducing Oxidative Stress Through Upregulating Hepatic Zinc and Metallothioneins.
Su W, Feng M, Liu Y, Cao R, Liu Y, Tang J, Pan K, Lan R, Mao Z
Frontiers in pharmacology 2021;12:721471
Frontiers in pharmacology 2021;12:721471
The Downregulation of eIF3a Contributes to Vemurafenib Resistance in Melanoma by Activating ERK via PPP2R1B.
Jiang SL, Wang ZB, Zhu T, Jiang T, Fei JF, Liu C, Luo C, Cheng Y, Liu ZQ
Frontiers in pharmacology 2021;12:720619
Frontiers in pharmacology 2021;12:720619
CXCL5 Downregulation in Villous Tissue Is Correlated With Recurrent Spontaneous Abortion.
Zhang S, Ding J, Wang J, Yin T, Zhang Y, Yang J
Frontiers in immunology 2021;12:717483
Frontiers in immunology 2021;12:717483
Protective Effect of Remdesivir Against Pulmonary Fibrosis in Mice.
Li X, Liu R, Cui Y, Liang J, Bi Z, Li S, Miao Y, Zhang L, Li X, Zhou H, Yang C
Frontiers in pharmacology 2021;12:692346
Frontiers in pharmacology 2021;12:692346
Chlorogenic Acid Ameliorates Damage Induced by Fluorene-9-Bisphenol in Porcine Sertoli Cells.
Zhang S, Sun B, Wang D, Liu Y, Li J, Qi J, Zhang Y, Bai C, Liang S
Frontiers in pharmacology 2021;12:678772
Frontiers in pharmacology 2021;12:678772
Human umbilical cord-derived mesenchymal stem cell therapy ameliorates lupus through increasing CD4+ T cell senescence via MiR-199a-5p/Sirt1/p53 axis.
Cheng T, Ding S, Liu S, Li Y, Sun L
Theranostics 2021;11(2):893-905
Theranostics 2021;11(2):893-905
circCDYL2, Overexpressed in Highly Migratory Colorectal Cancer Cells, Promotes Migration by Binding to Ezrin.
Li X, Wang J, Long H, Lin W, Wang H, Chen Y, Yuan Q, Li X
Frontiers in oncology 2021;11:716073
Frontiers in oncology 2021;11:716073
The Role of KDM2B and EZH2 in Regulating the Stemness in Colorectal Cancer Through the PI3K/AKT Pathway.
Sanches JGP, Song B, Zhang Q, Cui X, Yabasin IB, Ntim M, Li X, He J, Zhang Y, Mao J, Lu Y, Li L
Frontiers in oncology 2021;11:637298
Frontiers in oncology 2021;11:637298
Expression and prognostic potential of PLEK2 in head and neck squamous cell carcinoma based on bioinformatics analysis.
Wang J, Sun Z, Wang J, Tian Q, Huang R, Wang H, Wang X, Han F
Cancer medicine 2021 Sep;10(18):6515-6533
Cancer medicine 2021 Sep;10(18):6515-6533
Supervillin Contributes to LPS-induced Inflammatory Response in THP-1 Cell-derived Macrophages.
Zhou J, Que Y, Pan L, Li X, Zhu C, Jin L, Li S
Inflammation 2021 Sep 3;
Inflammation 2021 Sep 3;
Therapy of spinal cord injury by zinc modified gold nanoclusters via immune-suppressing strategies.
Lin S, Li D, Zhou Z, Xu C, Mei X, Tian H
Journal of nanobiotechnology 2021 Sep 20;19(1):281
Journal of nanobiotechnology 2021 Sep 20;19(1):281
TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity.
Bi J, Cheng C, Zheng C, Huang C, Zheng X, Wan X, Chen YH, Tian Z, Sun H
Science advances 2021 Sep 17;7(38):eabi6515
Science advances 2021 Sep 17;7(38):eabi6515
Yixin-Fumai granules improve sick sinus syndrome in aging mice through Nrf-2/HO-1 pathway: A new target for sick sinus syndrome.
Zhang H, Li L, Hao M, Chen K, Lu Y, Qi J, Chen W, Ren L, Cai X, Chen C, Liu Z, Zhao B, Li Z, Hou P
Journal of ethnopharmacology 2021 Sep 15;277:114254
Journal of ethnopharmacology 2021 Sep 15;277:114254
MicroRNA‑8063 targets heterogeneous nuclear ribonucleoprotein AB to inhibit the self‑renewal of colorectal cancer stem cells via the Wnt/β‑catenin pathway.
Chen ZQ, Yuan T, Jiang H, Yang YY, Wang L, Fu RM, Luo SQ, Zhang T, Wu ZY, Wen KM
Oncology reports 2021 Oct;46(4)
Oncology reports 2021 Oct;46(4)
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
Li XJ, Zhang YY, Fu YH, Zhang H, Li HX, Li QF, Li HL, Tan RK, Jiang CX, Jiang W, Li ZX, Luo C, Lu BX, Dang YJ
Acta pharmacologica Sinica 2021 Oct;42(10):1556-1566
Acta pharmacologica Sinica 2021 Oct;42(10):1556-1566
Cucurbit[7]uril as a Broad-Spectrum Antiviral Agent against Diverse RNA Viruses.
Quan J, Zhang X, Ding Y, Li S, Qiu Y, Wang R, Zhou X
Virologica Sinica 2021 Oct;36(5):1165-1176
Virologica Sinica 2021 Oct;36(5):1165-1176
ZBP1-MLKL necroptotic signaling potentiates radiation-induced antitumor immunity via intratumoral STING pathway activation.
Yang Y, Wu M, Cao D, Yang C, Jin J, Wu L, Hong X, Li W, Lu L, Li J, Wang X, Meng X, Zhang Z, Cheng J, Ye Y, Xiao H, Yu J, Deng L
Science advances 2021 Oct 8;7(41):eabf6290
Science advances 2021 Oct 8;7(41):eabf6290
NORHA, a novel follicular atresia-related lncRNA, promotes porcine granulosa cell apoptosis via the miR-183-96-182 cluster and FoxO1 axis.
Yao W, Pan Z, Du X, Zhang J, Liu H, Li Q
Journal of animal science and biotechnology 2021 Oct 7;12(1):103
Journal of animal science and biotechnology 2021 Oct 7;12(1):103
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Wang D, He J, Dong J, Wu S, Liu S, Zhu H, Xu T
Cancer letters 2021 Oct 28;519:2-19
Cancer letters 2021 Oct 28;519:2-19
Frugoside delays osteoarthritis progression via inhibiting miR-155-modulated synovial macrophage M1 polarization.
Wang H, Zhang H, Fan K, Zhang D, Hu A, Zeng X, Liu YL, Tan G, Wang H
Rheumatology (Oxford, England) 2021 Oct 2;60(10):4899-4909
Rheumatology (Oxford, England) 2021 Oct 2;60(10):4899-4909
Naringin Promotes Skeletal Muscle Fiber Remodeling by the AdipoR1-APPL1-AMPK Signaling Pathway.
Li P, Zhang S, Song H, Traore SS, Li J, Raubenheimer D, Cui Z, Kou G
Journal of agricultural and food chemistry 2021 Oct 13;69(40):11890-11899
Journal of agricultural and food chemistry 2021 Oct 13;69(40):11890-11899
Arsenic trioxide induces expression of BCL-2 expression via NF-κB and p38 MAPK signaling pathways in BEAS-2B cells during apoptosis.
Tang J, Yao C, Liu Y, Yuan J, Wu L, Hosoi K, Yu S, Huang C, Wei H, Chen G
Ecotoxicology and environmental safety 2021 Oct 1;222:112531
Ecotoxicology and environmental safety 2021 Oct 1;222:112531
Reduced activity of intestinal surface Na+/H+ exchanger NHE3 is a key factor for induction of diarrhea after PEDV infection in neonatal piglets.
Song Z, Yan T, Ran L, Niu Z, Zhang Y, Kan Z, Xu S, Zhang S, Zhang J, Zou H, Lei C
Virology 2021 Nov;563:64-73
Virology 2021 Nov;563:64-73
Tripartite motif-containing protein 16 protects against myocardial ischemia/reperfusion injury by affecting the Keap1/Nrf2 axis.
Cui Q, Yan L
Cell and tissue research 2021 Nov;386(2):349-363
Cell and tissue research 2021 Nov;386(2):349-363
EGFR and ERK activation resists flavonoid quercetin-induced anticancer activities in human cervical cancer cells in vitro.
Chen X, Xu P, Zhang H, Su X, Guo L, Zhou X, Wang J, Huang P, Zhang Q, Sun R
Oncology letters 2021 Nov;22(5):754
Oncology letters 2021 Nov;22(5):754
Guaiazulene derivative 1,2,3,4-tetrahydroazuleno[1,2-b] tropone reduces the production of ATP by inhibiting electron transfer complex II.
Kasami C, Yamaguchi JI, Inoue H
FEBS open bio 2021 Nov;11(11):2921-2932
FEBS open bio 2021 Nov;11(11):2921-2932
Vagus nerve stimulation mediates microglia M1/2 polarization via inhibition of TLR4 pathway after ischemic stroke.
Zhang L, Liu Y, Wang S, Long L, Zang Q, Ma J, Yu L, Jia G
Biochemical and biophysical research communications 2021 Nov 5;577:71-79
Biochemical and biophysical research communications 2021 Nov 5;577:71-79
Type IIB PKA is highly expressed in β cells and controls cell proliferation via regulating Cyclin D1 expression.
Jiang Y, Zhu L, Wu D, Ni Y, Huang C, Ye H, Yang Y, Liu R, Li Y
The FEBS journal 2021 Nov 28;
The FEBS journal 2021 Nov 28;
Golgi Phosphoprotein 3 Confers Radioresistance via Stabilizing EGFR in Lung Adenocarcinoma.
Chen G, Kong P, Yang M, Hu W, Prise KM, Yu KN, Cui S, Qin F, Meng G, Almahi WA, Nie L, Han W
International journal of radiation oncology, biology, physics 2021 Nov 26;
International journal of radiation oncology, biology, physics 2021 Nov 26;
A network pharmacology approach to reveal the pharmacological targets and biological mechanism of compound kushen injection for treating pancreatic cancer based on WGCNA and in vitro experiment validation.
Wu C, Huang ZH, Meng ZQ, Fan XT, Lu S, Tan YY, You LM, Huang JQ, Stalin A, Ye PZ, Wu ZS, Zhang JY, Liu XK, Zhou W, Zhang XM, Wu JR
Chinese medicine 2021 Nov 22;16(1):121
Chinese medicine 2021 Nov 22;16(1):121
1,10-Seco-Eudesmane sesquiterpenoids as a new type of anti-neuroinflammatory agents by suppressing TLR4/NF-κB/MAPK pathways.
Tang JJ, Wang MR, Dong S, Huang LF, He QR, Gao JM
European journal of medicinal chemistry 2021 Nov 15;224:113713
European journal of medicinal chemistry 2021 Nov 15;224:113713
Iptakalim alleviates synaptic damages via targeting mitochondrial ATP-sensitive potassium channel in depression.
Guo W, Tang ZY, Cai ZY, Zhao WE, Yang J, Wang XP, Ji J, Huang XX, Sun XL
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21581
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21581
Characterization of ALTO-encoding circular RNAs expressed by Merkel cell polyomavirus and trichodysplasia spinulosa polyomavirus.
Yang R, Lee EE, Kim J, Choi JH, Kolitz E, Chen Y, Crewe C, Salisbury NJH, Scherer PE, Cockerell C, Smith TR, Rosen L, Verlinden L, Galloway DA, Buck CB, Feltkamp MC, Sullivan CS, Wang RC
PLoS pathogens 2021 May;17(5):e1009582
PLoS pathogens 2021 May;17(5):e1009582
Plasma exosomes induce inflammatory immune response in patients with acute myocardial infarction.
Gong Z, Wen M, Zhang W, Yu L, Huang C, Xu Y, Xia Z, Xu M, Xu J, Liang Q, Bao H, Cheng X
Archives of physiology and biochemistry 2021 May 5;:1-9
Archives of physiology and biochemistry 2021 May 5;:1-9
Extracellular vesicles-based pre-targeting strategy enables multi-modal imaging of orthotopic colon cancer and image-guided surgery.
Jing B, Qian R, Jiang D, Gai Y, Liu Z, Guo F, Ren S, Gao Y, Lan X, An R
Journal of nanobiotechnology 2021 May 22;19(1):151
Journal of nanobiotechnology 2021 May 22;19(1):151
Functional domains and amino acid residues of Japanese eel IRF1, AjIRF1, regulate its nuclear import and IFN/Mx promoter activation.
Li W, Ling L, Wang Z, Liang Y, Huang W, Nie P, Huang B
Developmental and comparative immunology 2021 Mar;116:103923
Developmental and comparative immunology 2021 Mar;116:103923
Inhibition of ERAD synergizes with FTS to eradicate pancreatic cancer cells.
Du R, Sullivan DK, Azizian NG, Liu Y, Li Y
BMC cancer 2021 Mar 6;21(1):237
BMC cancer 2021 Mar 6;21(1):237
The combination of G-CSF and AMD3100 mobilizes bone marrow-derived stem cells to protect against cisplatin-induced acute kidney injury in mice.
Chen Z, Ren X, Ren R, Wang Y, Shang J
Stem cell research & therapy 2021 Mar 24;12(1):209
Stem cell research & therapy 2021 Mar 24;12(1):209
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Han D, Xu Y, Peng WP, Feng F, Wang Z, Gu C, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
lncRNA Ttc3-209 Promotes the Apoptosis of Retinal Ganglion Cells in Retinal Ischemia Reperfusion Injury by Targeting the miR-484/Wnt8a Axis.
Zhang R, Feng Y, Lu J, Ge Y, Li H
Investigative ophthalmology & visual science 2021 Mar 1;62(3):13
Investigative ophthalmology & visual science 2021 Mar 1;62(3):13
Sesamin induces cell cycle arrest and apoptosis through p38/C-Jun N-terminal kinase mitogen-activated protein kinase pathways in human colorectal cancer cells.
Wang X, Qiao J, Zou C, Zhao Y, Huang Y
Anti-cancer drugs 2021 Mar 1;32(3):248-256
Anti-cancer drugs 2021 Mar 1;32(3):248-256
Pharmacological effects of indole alkaloids from Alstonia scholaris (L.) R. Br. on pulmonary fibrosis in vivo.
Zhao YL, Pu SB, Qi Y, Wu BF, Shang JH, Liu YP, Hu D, Luo XD
Journal of ethnopharmacology 2021 Mar 1;267:113506
Journal of ethnopharmacology 2021 Mar 1;267:113506
Glycine alleviates fluoride-induced oxidative stress, apoptosis and senescence in a porcine testicular Sertoli cell line.
Liu Y, Sun B, Zhang S, Li J, Qi J, Bai C, Zhang J, Liang S
Reproduction in domestic animals = Zuchthygiene 2021 Jun;56(6):884-896
Reproduction in domestic animals = Zuchthygiene 2021 Jun;56(6):884-896
Alternative splicing transitions associate with emerging atrophy phenotype during denervation-induced skeletal muscle atrophy.
Qiu J, Wu L, Chang Y, Sun H, Sun J
Journal of cellular physiology 2021 Jun;236(6):4496-4514
Journal of cellular physiology 2021 Jun;236(6):4496-4514
Melatonin ameliorates cypermethrin-induced impairments by regulating oxidative stress, DNA damage and apoptosis in porcine Sertoli cells.
Li J, Sun BX, Wang DL, Liu Y, Qi JJ, Nie XW, Bai CY, Zhang JB, Liang S
Theriogenology 2021 Jun;167:67-76
Theriogenology 2021 Jun;167:67-76
Resolving the graft ischemia-reperfusion injury during liver transplantation at the single cell resolution.
Wang L, Li J, He S, Liu Y, Chen H, He S, Yin M, Zou D, Chen S, Luo T, Yu X, Wan X, Huang S, Guo Z, He X
Cell death & disease 2021 Jun 8;12(6):589
Cell death & disease 2021 Jun 8;12(6):589
Ameliorative effects of eosinophil deficiency on immune response, endoplasmic reticulum stress, apoptosis, and autophagy in fungus-induced allergic lung inflammation.
Wang S, Jiang Z, Li L, Zhang J, Zhang C, Shao C
Respiratory research 2021 Jun 7;22(1):173
Respiratory research 2021 Jun 7;22(1):173
Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.
Chen Z, Chen Y, Li Y, Lian W, Zheng K, Zhang Y, Zhang Y, Lin C, Liu C, Sun F, Sun X, Wang J, Zhao L, Ke Y
Cell death & disease 2021 Jun 15;12(6):615
Cell death & disease 2021 Jun 15;12(6):615
PI3K/AKT pathway mediates the antidepressant- and anxiolytic-like roles of hydrogen sulfide in streptozotocin-induced diabetic rats via promoting hippocampal neurogenesis.
Jiang W, Tang YY, Zhu WW, Li C, Zhang P, Li RQ, Chen YJ, Zou W, Tang XQ
Neurotoxicology 2021 Jul;85:201-208
Neurotoxicology 2021 Jul;85:201-208
AEG-1 Knockdown Sensitizes Glioma Cells to Radiation Through Impairing Homologous Recombination Via Targeting RFC5.
Zhao X, Sun Y, Sun X, Li J, Shi X, Liang Z, Ma Y, Zhang X
DNA and cell biology 2021 Jul;40(7):895-905
DNA and cell biology 2021 Jul;40(7):895-905
The role of SAMM50 in non-alcoholic fatty liver disease: from genetics to mechanisms.
Li Z, Shen W, Wu G, Qin C, Zhang Y, Wang Y, Song G, Xiao C, Zhang X, Deng G, Wang R, Wang X
FEBS open bio 2021 Jul;11(7):1893-1906
FEBS open bio 2021 Jul;11(7):1893-1906
Isoeucommin A attenuates kidney injury in diabetic nephropathy through the Nrf2/HO-1 pathway.
Huang Q, Ouyang DS, Liu Q
FEBS open bio 2021 Jul 6;
FEBS open bio 2021 Jul 6;
MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking.
Wang F, Chen X, Cheng H, Song L, Liu J, Caplan S, Zhu L, Wu JY
EMBO reports 2021 Jul 5;22(7):e52006
EMBO reports 2021 Jul 5;22(7):e52006
The plant hormone abscisic acid stimulates megakaryocyte differentiation from human iPSCs in vitro.
Huang W, Gu H, Zhan Z, Wang R, Song L, Zhang Y, Zhang Y, Li S, Li J, Zang Y, Li Y, Qian B
Platelets 2021 Jul 5;:1-9
Platelets 2021 Jul 5;:1-9
Theaflavin Promotes Mitochondrial Abundance and Glucose Absorption in Myotubes by Activating the CaMKK2-AMPK Signal Axis via Calcium-Ion Influx.
Qu Z, Liu A, Liu C, Tang Q, Zhan L, Xiao W, Huang J, Liu Z, Zhang S
Journal of agricultural and food chemistry 2021 Jul 28;69(29):8144-8159
Journal of agricultural and food chemistry 2021 Jul 28;69(29):8144-8159
Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model.
Duan A, Shen K, Li B, Li C, Zhou H, Kong R, Shao Y, Qin J, Yuan T, Ji J, Guo W, Wang X, Xue T, Li L, Huang X, Sun Y, Cai Z, Liu W, Liu F
Stem cell research & therapy 2021 Jul 28;12(1):427
Stem cell research & therapy 2021 Jul 28;12(1):427
SMAD4 Inhibits Granulosa Cell Apoptosis via the miR-183-96-182 Cluster and FoxO1 Axis.
Yao W, Wang S, Du X, Lin C, Zhang J, Pan Z, Li Q
Reproductive sciences (Thousand Oaks, Calif.) 2021 Jul 21;
Reproductive sciences (Thousand Oaks, Calif.) 2021 Jul 21;
Attractin Gene Deficiency in Rats Leads to Impairments in Both Activity and Spatial Learning and Memory.
Li XH, Xue C, Liu MQ, Zhang MY, Zhou Y, Xiao X, Wang J, Xu XJ, Shi Y, Zhang WN
Neuroscience 2021 Jul 1;466:101-108
Neuroscience 2021 Jul 1;466:101-108
Betulinic acid attenuated bleomycin-induced pulmonary fibrosis by effectively intervening Wnt/β-catenin signaling.
Li X, Liu X, Deng R, Gao S, Jiang Q, Liu R, Li H, Miao Y, Zhai Y, Zhang S, Wang Z, Ren Y, Ning W, Zhou H, Yang C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;81:153428
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;81:153428
ETV5 Regulates Hepatic Fatty Acid Metabolism Through PPAR Signaling Pathway.
Mao Z, Feng M, Li Z, Zhou M, Xu L, Pan K, Wang S, Su W, Zhang W
Diabetes 2021 Jan;70(1):214-226
Diabetes 2021 Jan;70(1):214-226
Identification and Bioinformatic Assessment of circRNA Expression After RMI1 Knockdown and Ionizing Radiation Exposure.
Sun Y, Fang L, Yang M, He N, Wang J, Zhang M, Ji K, Wang Q, Liu Y, Du L, Wang Y, Xu C, Liu Q
DNA and cell biology 2021 Jan;40(1):80-92
DNA and cell biology 2021 Jan;40(1):80-92
NADPH levels affect cellular epigenetic state by inhibiting HDAC3-Ncor complex.
Li W, Kou J, Qin J, Li L, Zhang Z, Pan Y, Xue Y, Du W
Nature metabolism 2021 Jan;3(1):75-89
Nature metabolism 2021 Jan;3(1):75-89
Libertellenone H, a Natural Pimarane Diterpenoid, Inhibits Thioredoxin System and Induces ROS-Mediated Apoptosis in Human Pancreatic Cancer Cells.
Zhang W, Zhu Y, Yu H, Liu X, Jiao B, Lu X
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
Yang J, Cao LL, Wang XP, Guo W, Guo RB, Sun YQ, Xue TF, Cai ZY, Ji J, Cheng H, Sun XL
Cell death & disease 2021 Jan 6;12(1):23
Cell death & disease 2021 Jan 6;12(1):23
TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy.
Zhang HT, Zeng Q, Wu B, Lu J, Tong KL, Lin J, Liu QY, Xu L, Yang J, Liu X, Liu W, Zhang YF, Lian Q, Liu L, Gao X
Cell death & disease 2021 Jan 6;12(1):21
Cell death & disease 2021 Jan 6;12(1):21
A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA.
Sun H, Huang Y, Mei S, Xu F, Liu X, Zhao F, Yin L, Zhang D, Wei L, Wu C, Ma S, Wang J, Cen S, Liang C, Hu S, Guo F
Cell reports 2021 Jan 5;34(1):108586
Cell reports 2021 Jan 5;34(1):108586
Formaldehyde induces ferroptosis in hippocampal neuronal cells by upregulation of the Warburg effect.
Li XN, Yang SQ, Li M, Li XS, Tian Q, Xiao F, Tang YY, Kang X, Wang CY, Zou W, Zhang P, Tang XQ
Toxicology 2021 Jan 30;448:152650
Toxicology 2021 Jan 30;448:152650
CHIP protects against MPP+/MPTP-induced damage by regulating Drp1 in two models of Parkinson's disease.
Hu Z, Mao C, Wang H, Zhang Z, Zhang S, Luo H, Tang M, Yang J, Yuan Y, Wang Y, Liu Y, Fan L, Zhang Q, Yao D, Liu F, Schisler JC, Shi C, Xu Y
Aging 2021 Jan 2;13(1):1458-1472
Aging 2021 Jan 2;13(1):1458-1472
BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.
Xue W, Yao X, Ting G, Ling J, Huimin L, Yuan Q, Chun Z, Ming Z, Yuanzhen Z
Environmental pollution (Barking, Essex : 1987) 2021 Jan 1;268(Pt B):115748
Environmental pollution (Barking, Essex : 1987) 2021 Jan 1;268(Pt B):115748
Oral Administration of Probiotic Bifidobacterium breve Improves Facilitation of Hippocampal Memory Extinction via Restoration of Aberrant Higher Induction of Neuropsin in an MPTP-Induced Mouse Model of Parkinson's Disease.
Ishii T, Furuoka H, Kaya M, Kuhara T
Biomedicines 2021 Feb 8;9(2)
Biomedicines 2021 Feb 8;9(2)
A novel tonicity-responsive microRNA miR-23a-5p modulates renal cell survival under osmotic stress through targeting heat shock protein 70 HSPA1B.
Kang K, Liao X, Li Q, Chen J, Niu Y, Zeng Y, Xia S, Zeng L, Liu S, Gou D
American journal of physiology. Cell physiology 2021 Feb 1;320(2):C225-C239
American journal of physiology. Cell physiology 2021 Feb 1;320(2):C225-C239
Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology.
Zhang Y, Chen X, Wang Q, Du C, Lu W, Yuan H, Zhang Z, Li D, Ling X, Ren X, Zhao Y, Su Q, Xing Z, Qin Y, Yang X, Shen Y, Wu H, Qi Y
Journal of molecular medicine (Berlin, Germany) 2021 Dec;99(12):1797-1813
Journal of molecular medicine (Berlin, Germany) 2021 Dec;99(12):1797-1813
Integrated Metabolomics and Transcriptomics Analyses Reveal Metabolic Landscape in Neuronal Cells during JEV Infection.
Li M, Yang J, Ye C, Bian P, Yang X, Zhang H, Luo C, Xue Z, Lei Y, Lian J
Virologica Sinica 2021 Dec;36(6):1554-1565
Virologica Sinica 2021 Dec;36(6):1554-1565
Decreased NHE3 activity in intestinal epithelial cells in TGEV and PEDV-induced piglet diarrhea.
Niu Z, Zhang Y, Kan Z, Ran L, Yan T, Xu S, Zhang S, Zhang J, Zou H, Song Z
Veterinary microbiology 2021 Dec;263:109263
Veterinary microbiology 2021 Dec;263:109263
The STING antagonist H-151 ameliorates psoriasis via suppression of STING/NF-κB-mediated inflammation.
Pan Y, You Y, Sun L, Sui Q, Liu L, Yuan H, Chen C, Liu J, Wen X, Dai L, Sun H
British journal of pharmacology 2021 Dec;178(24):4907-4922
British journal of pharmacology 2021 Dec;178(24):4907-4922
Mbd2 deficiency alleviates retinal cell apoptosisvia the miR-345-5p/Atf1 axis in high glucoseinjury and streptozotocin-induced diabetic mice.
Ge Y, Zhang R, Feng Y, Lu J, Li H
Molecular therapy. Nucleic acids 2021 Dec 3;26:1201-1214
Molecular therapy. Nucleic acids 2021 Dec 3;26:1201-1214
TRPV4 inhibitor HC067047 produces antidepressant-like effect in LPS-induced depression mouse model.
Li W, Xu Y, Liu Z, Shi M, Zhang Y, Deng Y, Zhong X, Chen L, He J, Zeng J, Luo M, Cao W, Wan W
Neuropharmacology 2021 Dec 15;201:108834
Neuropharmacology 2021 Dec 15;201:108834
Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.
Liu C, Qu J, Wu M, Huang X, Li L
Ecotoxicology and environmental safety 2021 Dec 1;225:112792
Ecotoxicology and environmental safety 2021 Dec 1;225:112792
NOD2 deficiency confers a pro-tumorigenic macrophage phenotype to promote lung adenocarcinoma progression.
Wang Y, Miao Z, Qin X, Li B, Han Y
Journal of cellular and molecular medicine 2021 Aug;25(15):7545-7558
Journal of cellular and molecular medicine 2021 Aug;25(15):7545-7558
Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Ameliorate HaCaT Cell Photo-Aging.
Liu SJ, Meng MY, Han S, Gao H, Zhao YY, Yang Y, Lin ZY, Yang LR, Zhu K, Han R, Huang WW, Wang RQ, Yang LL, Wang WJ, Li L, Wang XD, Hou ZL, Liao LW, Yang L
Rejuvenation research 2021 Aug;24(4):283-293
Rejuvenation research 2021 Aug;24(4):283-293
TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis.
Huang D, Xu B, Liu L, Wu L, Zhu Y, Ghanbarpour A, Wang Y, Chen FJ, Lyu J, Hu Y, Kang Y, Zhou W, Wang X, Ding W, Li X, Jiang Z, Chen J, Zhang X, Zhou H, Li JZ, Guo C, Zheng W, Zhang X, Li P, Melia T, Reinisch K, Chen XW
Cell metabolism 2021 Aug 3;33(8):1655-1670.e8
Cell metabolism 2021 Aug 3;33(8):1655-1670.e8
The E2F1/USP11 positive feedback loop promotes hepatocellular carcinoma metastasis and inhibits autophagy by activating ERK/mTOR pathway.
Qiao L, Zhang Q, Sun Z, Liu Q, Wu Z, Hu W, Bao S, Yang Q, Liu L
Cancer letters 2021 Aug 28;514:63-78
Cancer letters 2021 Aug 28;514:63-78
High-Carbohydrate Diet Alleviates the Oxidative Stress, Inflammation and Apoptosis of Megalobrama amblycephala Following Dietary Exposure to Silver Nanoparticles.
Chen F, Zhao CY, Guan JF, Liu XC, Li XF, Xie DZ, Xu C
Antioxidants (Basel, Switzerland) 2021 Aug 25;10(9)
Antioxidants (Basel, Switzerland) 2021 Aug 25;10(9)
Triptolide impairs glycolysis by suppressing GATA4/Sp1/PFKP signaling axis in mouse Sertoli cells.
Zhang Y, Tang Y, Luo Y, Luo L, Shen F, Huang Z
Toxicology and applied pharmacology 2021 Aug 15;425:115606
Toxicology and applied pharmacology 2021 Aug 15;425:115606
KPNB1-mediated nuclear translocation of PD-L1 promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signaling pathway.
Du W, Zhu J, Zeng Y, Liu T, Zhang Y, Cai T, Fu Y, Zhang W, Zhang R, Liu Z, Huang JA
Cell death and differentiation 2021 Apr;28(4):1284-1300
Cell death and differentiation 2021 Apr;28(4):1284-1300
HSP/HSC70 activity is required for Bombyx mori nucleopolyhedrovirus replication at the early infectious phase.
Mao F, Zhu Y, Gao X, Chen X, Ngowo J, Miao M, Quan Y, Yu W
Microbial pathogenesis 2021 Apr;153:104647
Microbial pathogenesis 2021 Apr;153:104647
Salidroside Attenuates Doxorubicin-Induced Cardiac Dysfunction Partially Through Activation of QKI/FoxO1 Pathway.
Yan F, Liu R, Zhuang X, Li R, Shi H, Gao X
Journal of cardiovascular translational research 2021 Apr;14(2):355-364
Journal of cardiovascular translational research 2021 Apr;14(2):355-364
Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1.
Yang F, Zhang Y, Zhu J, Wang J, Jiang Z, Zhao C, Yang Q, Huang Y, Yao W, Pang W, Han L, Zhou J
Frontiers in bioengineering and biotechnology 2020;8:647
Frontiers in bioengineering and biotechnology 2020;8:647
Neural Tube Defects and ZIC4 Hypomethylation in Relation to Polycyclic Aromatic Hydrocarbon Exposure.
Huang Y, Lin S, Wang C, Pi X, Jin L, Li Z, Wang L, Ren A
Frontiers in cell and developmental biology 2020;8:582661
Frontiers in cell and developmental biology 2020;8:582661
Identification of Transcriptional Variation in Aortic Remodeling Using a Murine Transverse Aortic Constriction (TAC) Model.
Zhang X, Feng T, Zeng XI, Liang H, Situ B, Zhang Q, Zhou F, Chen Y, Wang T, Cai D, Lin X, Xiu J, Zheng L
Frontiers in cardiovascular medicine 2020;7:581362
Frontiers in cardiovascular medicine 2020;7:581362
Similar Repair Effects of Human Placenta, Bone Marrow Mesenchymal Stem Cells, and Their Exosomes for Damaged SVOG Ovarian Granulosa Cells.
Chen S, Wang Y, Liao L, Meng L, Li J, Shi C, Han H, Zheng X, Shen H
Stem cells international 2020;2020:8861557
Stem cells international 2020;2020:8861557
Beneficial Effects of Crocin against Depression via Pituitary Adenylate Cyclase-Activating Polypeptide.
Lu L, Wu D, Wang K, Tang J, Chen G
BioMed research international 2020;2020:3903125
BioMed research international 2020;2020:3903125
Anti-Inflammatory and Antioxidant Effect of Eucommia ulmoides Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-κB Pathway.
Gao W, Feng Z, Zhang S, Wu B, Geng X, Fan G, Duan Y, Li K, Liu K, Peng C
BioMed research international 2020;2020:1860637
BioMed research international 2020;2020:1860637
Skp2 modulates proliferation, senescence and tumorigenesis of glioma.
Wu J, Su HK, Yu ZH, Xi SY, Guo CC, Hu ZY, Qu Y, Cai HP, Zhao YY, Zhao HF, Chen FR, Huang YF, To ST, Feng BH, Sai K, Chen ZP, Wang J
Cancer cell international 2020;20:71
Cancer cell international 2020;20:71
HCK can serve as novel prognostic biomarker and therapeutic target for Breast Cancer patients.
Zhu X, Zhang Y, Bai Y, Gu X, Chen G, Sun L, Wang Y, Qiao X, Ma Q, Zhu T, Bu J, Xue J, Liu C
International journal of medical sciences 2020;17(17):2773-2789
International journal of medical sciences 2020;17(17):2773-2789
Repression of FGF signaling is responsible for Dnmt3b inhibition and impaired de novo DNA methylation during early development of in vitro fertilized embryos.
Fu W, Yue Y, Miao K, Xi G, Zhang C, Wang W, An L, Tian J
International journal of biological sciences 2020;16(15):3085-3099
International journal of biological sciences 2020;16(15):3085-3099
G Protein-Coupled Receptor 109A Maintains the Intestinal Integrity and Protects Against ETEC Mucosal Infection by Promoting IgA Secretion.
Gong Y, Jin X, Yuan B, Lv Y, Yan G, Liu M, Xie C, Liu J, Tang Y, Gao H, Zhu Y, Huang Y, Wang W
Frontiers in immunology 2020;11:583652
Frontiers in immunology 2020;11:583652
Integration of Transcriptomics and Metabolomics Reveals the Antitumor Mechanism Underlying Shikonin in Colon Cancer.
Chen Y, Gao Y, Yi X, Zhang J, Chen Z, Wu Y
Frontiers in pharmacology 2020;11:544647
Frontiers in pharmacology 2020;11:544647
Possible Roles of Proinflammatory Signaling in Keratinocytes Through Aryl Hydrocarbon Receptor Ligands for the Development of Squamous Cell Carcinoma.
Sato Y, Fujimura T, Hidaka T, Lyu C, Tanita K, Matsushita S, Yamamoto M, Aiba S
Frontiers in immunology 2020;11:534323
Frontiers in immunology 2020;11:534323
Control the fate of human umbilical cord mesenchymal stem cells with dual-enzymatically cross-linked gelatin hydrogels for potential applications in nerve regeneration.
Li J, Gao F, Ma S, Zhang Y, Zhang J, Guan F, Yao M
Journal of tissue engineering and regenerative medicine 2020 Sep;14(9):1261-1271
Journal of tissue engineering and regenerative medicine 2020 Sep;14(9):1261-1271
miR-361-5p Mediates SMAD4 to Promote Porcine Granulosa Cell Apoptosis through VEGFA.
Ma M, Zhang J, Gao X, Yao W, Li Q, Pan Z
Biomolecules 2020 Sep 4;10(9)
Biomolecules 2020 Sep 4;10(9)
Neddylation promotes protein translocation between the cytoplasm and nucleus.
Li S, Fang W, Cui Y, Shi H, Chen J, Li L, Zhang L, Zhang X
Biochemical and biophysical research communications 2020 Sep 3;529(4):991-997
Biochemical and biophysical research communications 2020 Sep 3;529(4):991-997
EPS8 regulates an NLRP3 inflammasome-independent caspase-1 activation pathway in monosodium urate crystal-treated RAW264.7 macrophages.
Chuang JP, Kao CY, Lee JC, Ling P, Maa MC, Leu TH
Biochemical and biophysical research communications 2020 Sep 24;530(3):487-493
Biochemical and biophysical research communications 2020 Sep 24;530(3):487-493
RNA-binding protein CUGBP1 controls the differential INSR splicing in molecular subtypes of breast cancer cells and affects cell aggressiveness.
Huang G, Song C, Wang N, Qin T, Sui S, Obr A, Zeng L, Wood TL, Leroith D, Li M, Wu Y
Carcinogenesis 2020 Sep 24;41(9):1294-1305
Carcinogenesis 2020 Sep 24;41(9):1294-1305
Chrysin Inhibits Melanoma Tumor Metastasis via Interfering with the FOXM1/β-Catenin Signaling.
Yufei Z, Yuqi W, Binyue H, Lingchen T, Xi C, Hoffelt D, Fuliang H
Journal of agricultural and food chemistry 2020 Sep 2;68(35):9358-9367
Journal of agricultural and food chemistry 2020 Sep 2;68(35):9358-9367
Indole alkaloids from leaves of Alstonia scholaris (L.) R. Br. protect against emphysema in mice.
Zhao YL, Yang ZF, Wu BF, Shang JH, Liu YP, Wang XH, Luo XD
Journal of ethnopharmacology 2020 Sep 15;259:112949
Journal of ethnopharmacology 2020 Sep 15;259:112949
miR-203 inhibits cell proliferation and ERK pathway in prostate cancer by targeting IRS-1.
Meng Y, Hu X, Li S, Zeng X, Qiu L, Wei M, Wang Z, Han J
BMC cancer 2020 Oct 27;20(1):1028
BMC cancer 2020 Oct 27;20(1):1028
Identification of long-term survival-associated gene in breast cancer.
Ning S, Li H, Qiao K, Wang Q, Shen M, Kang Y, Yin Y, Liu J, Liu L, Hou S, Wang J, Xu S, Pang D
Aging 2020 Oct 20;12(20):20332-20349
Aging 2020 Oct 20;12(20):20332-20349
bta-miR-23a Regulates the Myogenic Differentiation of Fetal Bovine Skeletal Muscle-Derived Progenitor Cells by Targeting MDFIC Gene.
Hu X, Xing Y, Ren L, Wang Y, Li Q, Yang Q, Du M, Xu L, Willems L, Li J, Zhang L
Genes 2020 Oct 20;11(10)
Genes 2020 Oct 20;11(10)
Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage.
Fan C, Feng J, Tang C, Zhang Z, Feng Y, Duan W, Zhai M, Yan Z, Zhu L, Feng L, Zhu H, Luo E
Stem cell research & therapy 2020 Oct 15;11(1):442
Stem cell research & therapy 2020 Oct 15;11(1):442
Efficacy of a wound-dressing biomaterial on prevention of postinflammatory hyperpigmentation after suction blister epidermal grafting in stable vitiligo patients: a controlled assessor-blinded clinical study with in vitro bioactivity investigation.
Liu Z, Jiang M, Zhao J, Wang Q, Zhang C, Gao M, Gu M, Xiang L
Archives of dermatological research 2020 Nov;312(9):635-645
Archives of dermatological research 2020 Nov;312(9):635-645
The critical role of the hippocampal NLRP3 inflammasome in social isolation-induced cognitive impairment in male mice.
Niu L, Luo SS, Xu Y, Wang Z, Luo D, Yang H, Li W, He J, Zhong XL, Liu ZH, Zeng JY, Cao WY, Wan W
Neurobiology of learning and memory 2020 Nov;175:107301
Neurobiology of learning and memory 2020 Nov;175:107301
MitoQ attenuates brain damage by polarizing microglia towards the M2 phenotype through inhibition of the NLRP3 inflammasome after ICH.
Chen W, Guo C, Huang S, Jia Z, Wang J, Zhong J, Ge H, Yuan J, Chen T, Liu X, Hu R, Yin Y, Feng H
Pharmacological research 2020 Nov;161:105122
Pharmacological research 2020 Nov;161:105122
The B7-H4 gene induces immune escape partly via upregulating the PD-1/Stat3 pathway in non-small cell lung cancer.
Yuan L, Ye J, Fan D
Human immunology 2020 May;81(5):254-261
Human immunology 2020 May;81(5):254-261
Protein target identification of ginsenosides in skeletal muscle tissues: discovery of natural small-molecule activators of muscle-type creatine kinase.
Chen F, Zhu K, Chen L, Ouyang L, Chen C, Gu L, Jiang Y, Wang Z, Lin Z, Zhang Q, Shao X, Dai J, Zhao Y
Journal of ginseng research 2020 May;44(3):461-474
Journal of ginseng research 2020 May;44(3):461-474
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, Shao X, Song N, Zhao Y, Li H, Yang G, Xu C, Wei C
Redox biology 2020 May;32:101514
Redox biology 2020 May;32:101514
Leptin mediates protection of hydrogen sulfide against 6-hydroxydopamine-induced Parkinson's disease: Involving enhancement in Warburg effect.
Yang SQ, Tian Q, Li D, He SQ, Hu M, Liu SY, Zou W, Chen YJ, Zhang P, Tang XQ
Neurochemistry international 2020 May;135:104692
Neurochemistry international 2020 May;135:104692
Neuropeptide Y1 receptor antagonist promotes osteoporosis and microdamage repair and enhances osteogenic differentiation of bone marrow stem cells via cAMP/PKA/CREB pathway.
Xie W, Li F, Han Y, Qin Y, Wang Y, Chi X, Xiao J, Li Z
Aging 2020 May 7;12(9):8120-8136
Aging 2020 May 7;12(9):8120-8136
A Novel Mechanism of bta-miR-210 in Bovine Early Intramuscular Adipogenesis.
Ren L, Li Q, Hu X, Yang Q, Du M, Xing Y, Wang Y, Li J, Zhang L
Genes 2020 May 29;11(6)
Genes 2020 May 29;11(6)
Crosstalk between androgen and Wnt/β-catenin leads to changes of wool density in FGF5-knockout sheep.
Zhang R, Li Y, Jia K, Xu X, Li Y, Zhao Y, Zhang X, Zhang J, Liu G, Deng S, Lian Z
Cell death & disease 2020 May 29;11(5):407
Cell death & disease 2020 May 29;11(5):407
Synergistic antifibrotic effects of miR-451 with miR-185 partly by co-targeting EphB2 on hepatic stellate cells.
Chen X, Zhang D, Wang Y, Chen K, Zhao L, Xu Y, Jiang H, Wang S
Cell death & disease 2020 May 28;11(5):402
Cell death & disease 2020 May 28;11(5):402
Synthesis and biological evaluations of N'-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents.
Li B, Zhu F, He F, Huang Q, Liu X, Wu T, Zhao T, Qiu Y, Wu Z, Xue Y, Fang M
Bioorganic chemistry 2020 Mar;96:103592
Bioorganic chemistry 2020 Mar;96:103592
Mbd2 Mediates Retinal Cell Apoptosis by Targeting the lncRNA Mbd2-AL1/miR-188-3p/Traf3 Axis in Ischemia/Reperfusion Injury.
Ge Y, Zhang R, Feng Y, Li H
Molecular therapy. Nucleic acids 2020 Mar 6;19:1250-1265
Molecular therapy. Nucleic acids 2020 Mar 6;19:1250-1265
Anti-neuroinflammatory effect of 3,4-dihydroxybenzaldehyde in ischemic stroke.
Li X, Xiang B, Shen T, Xiao C, Dai R, He F, Lin Q
International immunopharmacology 2020 Mar 3;82:106353
International immunopharmacology 2020 Mar 3;82:106353
Yueju-Ganmaidazao Decoction confers rapid antidepressant-like effects and the involvement of suppression of NMDA/NO/cGMP signaling.
Zhang H, Sun Y, Qian S, Ge R, Guo X, Shen Q, Sheng L, Nie C, Zhang Y, Yao Y, Zhou T, Wang W, Xue W, Chen G
Journal of ethnopharmacology 2020 Mar 25;250:112380
Journal of ethnopharmacology 2020 Mar 25;250:112380
The developmental and experience-dependent expression of IGF-2 in mice visual cortex.
Luo Y, Liu Z, Luo S, Wang X, Tao L
Neuroscience letters 2020 Mar 16;721:134828
Neuroscience letters 2020 Mar 16;721:134828
Overexpression of NRF1-742 or NRF1-772 Reduces Arsenic-Induced Cytotoxicity and Apoptosis in Human HaCaT Keratinocytes.
Wang S, Cheng H, Wang L, Zhao R, Guan D
International journal of molecular sciences 2020 Mar 16;21(6)
International journal of molecular sciences 2020 Mar 16;21(6)
Circular RNA hsa_circ_0008285 inhibits colorectal cancer cell proliferation and migration via the miR-382-5p/PTEN axis.
Wang J, Luo J, Liu G, Li X
Biochemical and biophysical research communications 2020 Jun 25;527(2):503-510
Biochemical and biophysical research communications 2020 Jun 25;527(2):503-510
Hepatic HuR modulates lipid homeostasis in response to high-fat diet.
Zhang Z, Zong C, Jiang M, Hu H, Cheng X, Ni J, Yi X, Jiang B, Tian F, Chang MW, Su W, Zhu L, Li J, Xiang X, Miao C, Gorospe M, de Cabo R, Dou Y, Ju Z, Yang J, Jiang C, Yang Z, Wang W
Nature communications 2020 Jun 16;11(1):3067
Nature communications 2020 Jun 16;11(1):3067
Melatonin regulates mitochondrial dynamics and alleviates neuron damage in prion diseases.
Zhang X, Zhao D, Wu W, Ali Shah SZ, Lai M, Yang D, Li J, Guan Z, Li W, Gao H, Zhao H, Zhou X, Yang L
Aging 2020 Jun 10;12(11):11139-11151
Aging 2020 Jun 10;12(11):11139-11151
PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition.
Dong P, Fu H, Chen L, Zhang S, Zhang X, Li H, Wu D, Ji X
Journal of cellular and molecular medicine 2020 Jul;24(14):8221-8235
Journal of cellular and molecular medicine 2020 Jul;24(14):8221-8235
A novel microRNA and its pfk target control growth length in the freshwater shrimp Neocaridina heteropoda.
Li R, Weng J, Ren L, Wang X, Meng Q, Wang L, Sun J
The Journal of experimental biology 2020 Jul 8;223(Pt 13)
The Journal of experimental biology 2020 Jul 8;223(Pt 13)
Cortistatin ameliorates Ang II-induced proliferation of vascular smooth muscle cells by inhibiting autophagy through SSTR3 and SSTR5.
Wang Y, Zhang X, Chen W, Gao L, Li J, Song T, Chi J, Zhang X, Shi Z, Dong Y, Yin X, Liu Y
Life sciences 2020 Jul 15;253:117726
Life sciences 2020 Jul 15;253:117726
Nucleus-located PDK1 regulates growth, invasion and migration of breast cancer cells.
Gan D, Yue S, Jiang Y, Zhang D, Shi H, Qian H, Zhou T, Fang W, Yao M, Zuo G, Chen T
Life sciences 2020 Jul 15;253:117722
Life sciences 2020 Jul 15;253:117722
Autophagy inducer activates Nrf2-ARE pathway to attenuate aberrant alveolarization in neonatal rats with bronchopulmonary dysplasia.
Zhao X, Shi Y, Zhang D, Tong X, Sun Y, Xue X, Fu J
Life sciences 2020 Jul 1;252:117662
Life sciences 2020 Jul 1;252:117662
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Jiang YP, Ye RJ, Yang JM, Liu N, Zhang WJ, Ma L, Sun T, Niu JG, Zheng P, Yu JQ
Chemico-biological interactions 2020 Jan 5;315:108869
Chemico-biological interactions 2020 Jan 5;315:108869
Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis.
Feng J, Dai W, Mao Y, Wu L, Li J, Chen K, Yu Q, Kong R, Li S, Zhang J, Ji J, Wu J, Mo W, Xu X, Guo C
Journal of experimental & clinical cancer research : CR 2020 Jan 30;39(1):24
Journal of experimental & clinical cancer research : CR 2020 Jan 30;39(1):24
SSEA3 and Sialyl Lewis a Glycan Expression Is Controlled by B3GALT5 LTR through Lamin A-NFYA and SIRT1-STAT3 Signaling in Human ES Cells.
Cai BH, Lee HY, Chou CK, Wu PH, Huang HC, Chao CC, Chung HY, Kannagi R
Cells 2020 Jan 10;9(1)
Cells 2020 Jan 10;9(1)
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA2 phosphorylation in experimental ischemic stroke.
Cao C, Zhou J, Wu X, Qian Y, Hong Y, Mu J, Jin L, Zhu C, Li S
Cellular signalling 2020 Feb;66:109467
Cellular signalling 2020 Feb;66:109467
Pizotifen inhibits the proliferation and invasion of gastric cancer cells.
Jiang Y, Wang W, Wu X, Shi J
Experimental and therapeutic medicine 2020 Feb;19(2):817-824
Experimental and therapeutic medicine 2020 Feb;19(2):817-824
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABAA receptors.
Teoh J, Subramanian N, Pero ME, Bartolini F, Amador A, Kanber A, Williams D, Petri S, Yang M, Allen AS, Beal J, Haut SR, Frankel WN
Neurobiology of disease 2020 Feb;134:104632
Neurobiology of disease 2020 Feb;134:104632
Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma.
Ding XY, Hu HY, Huang KN, Wei RQ, Min J, Qi C, Tang H, Qin X
Cancer science 2020 Feb;111(2):489-501
Cancer science 2020 Feb;111(2):489-501
NCAPG Dynamically Coordinates the Myogenesis of Fetal Bovine Tissue by Adjusting Chromatin Accessibility.
Hu X, Xing Y, Fu X, Yang Q, Ren L, Wang Y, Li Q, Li J, Zhang L
International journal of molecular sciences 2020 Feb 13;21(4)
International journal of molecular sciences 2020 Feb 13;21(4)
Sodium butyrate causes α-synuclein degradation by an Atg5-dependent and PI3K/Akt/mTOR-related autophagy pathway.
Qiao CM, Sun MF, Jia XB, Shi Y, Zhang BP, Zhou ZL, Zhao LP, Cui C, Shen YQ
Experimental cell research 2020 Feb 1;387(1):111772
Experimental cell research 2020 Feb 1;387(1):111772
Oxidative stress-mediated hepatotoxicity in rats induced by ethanol extracts of different parts of Chloranthus serratus.
Sun S, Wang Y, Du Y, Sun Q, He L, Zhu E, Li J
Pharmaceutical biology 2020 Dec;58(1):1277-1289
Pharmaceutical biology 2020 Dec;58(1):1277-1289
Regulation of indoleamine 2, 3-dioxygenase in hippocampal microglia by NLRP3 inflammasome in lipopolysaccharide-induced depressive-like behaviors.
Zhang S, Zong Y, Ren Z, Hu J, Wu X, Xiao H, Qin S, Zhou G, Ma Y, Zhang Y, Yu J, Wang K, Lu G, Liu Q
The European journal of neuroscience 2020 Dec;52(11):4586-4601
The European journal of neuroscience 2020 Dec;52(11):4586-4601
Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.
Chen M, Ding Y, Ke Y, Zeng Y, Liu N, Zhong Y, Hua X, Li Z, Xiong Y, Wu C, Yu H
Artificial cells, nanomedicine, and biotechnology 2020 Dec;48(1):824-833
Artificial cells, nanomedicine, and biotechnology 2020 Dec;48(1):824-833
IGFBP6 regulates vascular smooth muscle cell proliferation and morphology via cyclin E-CDK2.
Wang Z, Qi Y, Wang R, Wu W, Li Z, Wang M, Liu R, Zhang C, Li W, Wang S
Journal of cellular physiology 2020 Dec;235(12):9538-9556
Journal of cellular physiology 2020 Dec;235(12):9538-9556
Inhibition of p38 MAPK regulates epileptic severity by decreasing expression levels of A1R and ENT1.
Zhou X, Chen Q, Huang H, Zhang J, Wang J, Chen Y, Peng Y, Zhang H, Zeng J, Feng Z, Xu Z
Molecular medicine reports 2020 Dec;22(6):5348-5357
Molecular medicine reports 2020 Dec;22(6):5348-5357
Tongmai formula improves cardiac function via regulating mitochondrial quality control in the myocardium with ischemia/reperfusion injury.
Zhao Y, Guo R, Li L, Li S, Fan G, Zhao X, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110897
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110897
Radiosensitization Effect of AGuIX, a Gadolinium-Based Nanoparticle, in Nonsmall Cell Lung Cancer.
Du Y, Sun H, Lux F, Xie Y, Du L, Xu C, Zhang H, He N, Wang J, Liu Y, Leduc G, Doussineau T, Ji K, Wang Q, Lin Z, Wang Y, Liu Q, Tillement O
ACS applied materials & interfaces 2020 Dec 23;12(51):56874-56885
ACS applied materials & interfaces 2020 Dec 23;12(51):56874-56885
Adiponectin protects HL-1 cardiomyocytes against rotenone-induced cytotoxicity through AMPK activation.
Li B, Zhang B, Liu N, Wu K, Ma Y, Zuo W, Ning Z, Liu Y, Sun C, Xiao Y, Tu T, Liu Q
Toxicology letters 2020 Dec 15;335:82-90
Toxicology letters 2020 Dec 15;335:82-90
Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer.
Li Y, Bai L, Yu H, Cai D, Wang X, Huang B, Peng S, Huang M, Cao G, Kaz AM, Grady WM, Wang J, Luo Y
Cancer research 2020 Dec 1;80(23):5203-5215
Cancer research 2020 Dec 1;80(23):5203-5215
Blood coagulation factor VIII D1241E polymorphism leads to a weak malectin interaction and reduction of factor VIII posttranslational modification and secretion.
Jiang N, Xiao Y, Liu Y, Liu W, Liu S
Experimental cell research 2020 Dec 1;397(1):112334
Experimental cell research 2020 Dec 1;397(1):112334
Homocysteine downregulates cardiac homeobox transcription factor NKX2.5 via IGFBP5.
Lai G, Wang L, Li Z, Zhao Y
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1380-H1386
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1380-H1386
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Yang YX, Yu S, Jia BX, Liu N, Wu A
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
Interplay of m6A and H3K27 trimethylation restrains inflammation during bacterial infection.
Wu C, Chen W, He J, Jin S, Liu Y, Yi Y, Gao Z, Yang J, Yang J, Cui J, Zhao W
Science advances 2020 Aug;6(34):eaba0647
Science advances 2020 Aug;6(34):eaba0647
WWP2 regulates SIRT1-STAT3 acetylation and phosphorylation involved in hypertensive angiopathy.
Zhang Y, You S, Tian Y, Lu S, Cao L, Sun Y, Zhang N
Journal of cellular and molecular medicine 2020 Aug;24(16):9041-9054
Journal of cellular and molecular medicine 2020 Aug;24(16):9041-9054
Myricetin ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting TGF-β signaling via targeting HSP90β.
Li X, Yu H, Liang L, Bi Z, Wang Y, Gao S, Wang M, Li H, Miao Y, Deng R, Ma L, Luan J, Li S, Liu M, Lin J, Zhou H, Yang C
Biochemical pharmacology 2020 Aug;178:114097
Biochemical pharmacology 2020 Aug;178:114097
Lnc-M2 controls M2 macrophage differentiation via the PKA/CREB pathway.
Chen Y, Li H, Ding T, Li J, Zhang Y, Wang J, Yang X, Chong T, Long Y, Li X, Gao F, Lyu X
Molecular immunology 2020 Aug;124:142-152
Molecular immunology 2020 Aug;124:142-152
Anti-Inflammatory Effect of Simonsinol on Lipopolysaccharide Stimulated RAW264.7 Cells through Inactivation of NF-κB Signaling Pathway.
Li LC, Pan ZH, Ning DS, Fu YX
Molecules (Basel, Switzerland) 2020 Aug 6;25(16)
Molecules (Basel, Switzerland) 2020 Aug 6;25(16)
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Zou YJ, Xu JJ, Wang X, Zhu YH, Wu Q, Wang JF
Veterinary sciences 2020 Aug 14;7(3)
Veterinary sciences 2020 Aug 14;7(3)
Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes.
Harmouch E, Seitlinger J, Chaddad H, Ubeaud-Sequier G, Barths J, Saidu S, Désaubry L, Grandemange S, Massfelder T, Fuhrmann G, Fioretti F, Dontenwill M, Benkirane-Jessel N, Idoux-Gillet Y
Scientific reports 2020 Aug 13;10(1):13750
Scientific reports 2020 Aug 13;10(1):13750
Design, synthesis and biological evaluation of a novel tubulin inhibitor SKLB0565 targeting the colchicine binding site.
Hu X, Li L, Zhang Q, Wang Q, Feng Z, Xu Y, Xia Y, Yu L
Bioorganic chemistry 2020 Apr;97:103695
Bioorganic chemistry 2020 Apr;97:103695
The E3 ubiquitin ligase Smurf2 regulates PARP1 stability to alleviate oxidative stress-induced injury in human umbilical vein endothelial cells.
Qian H, Zhang N, Wu B, Wu S, You S, Zhang Y, Sun Y
Journal of cellular and molecular medicine 2020 Apr;24(8):4600-4611
Journal of cellular and molecular medicine 2020 Apr;24(8):4600-4611
Monophosphoryl lipid A alleviated radiation-induced testicular injury through TLR4-dependent exosomes.
Liu Z, Cao K, Liao Z, Chen Y, Lei X, Wei Q, Liu C, Sun X, Yang Y, Cai J, Gao F
Journal of cellular and molecular medicine 2020 Apr;24(7):3917-3930
Journal of cellular and molecular medicine 2020 Apr;24(7):3917-3930
Inhibition of histone acetyltransferase GCN5 extends lifespan in both yeast and human cell lines.
Huang B, Zhong D, Zhu J, An Y, Gao M, Zhu S, Dang W, Wang X, Yang B, Xie Z
Aging cell 2020 Apr;19(4):e13129
Aging cell 2020 Apr;19(4):e13129
The ubiquitin-specific protease USP8 directly deubiquitinates SQSTM1/p62 to suppress its autophagic activity.
Peng H, Yang F, Hu Q, Sun J, Peng C, Zhao Y, Huang C
Autophagy 2020 Apr;16(4):698-708
Autophagy 2020 Apr;16(4):698-708
Exogenous H2S Induces Hrd1 S-sulfhydration and Prevents CD36 Translocation via VAMP3 Ubiquitylation in Diabetic Hearts.
Yu M, Du H, Wang B, Chen J, Lu F, Peng S, Sun Y, Liu N, Sun X, Shiyun D, Zhao Y, Wang Y, Zhao D, Lu F, Zhang W
Aging and disease 2020 Apr;11(2):286-300
Aging and disease 2020 Apr;11(2):286-300
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
Chen Z, Yuan SJ, Li K, Zhang Q, Li TF, An HC, Xu HZ, Yue Y, Han M, Xu YH, Komatsu N, Zhao L, Chen X
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
Xie C, Zhu J, Jiang Y, Chen J, Wang X, Geng S, Wu J, Zhong C, Li X, Meng Z
Theranostics 2019;9(16):4827-4840
Theranostics 2019;9(16):4827-4840
BH3 mimetic ABT-263 enhances the anticancer effects of apigenin in tumor cells with activating EGFR mutation.
Zhan Y, Wang Y, Qi M, Liang P, Ma Y, Li T, Li H, Dai C, An Z, Qi Y, Wu H, Shao H
Cell & bioscience 2019;9:60
Cell & bioscience 2019;9:60
The Binding of PD-L1 and Akt Facilitates Glioma Cell Invasion Upon Starvation via Akt/Autophagy/F-Actin Signaling.
Chen RQ, Xu XH, Liu F, Li CY, Li YJ, Li XR, Jiang GY, Hu F, Liu D, Pan F, Qiu XY, Chen XQ
Frontiers in oncology 2019;9:1347
Frontiers in oncology 2019;9:1347
Neuroprotective Effect of Echinacoside in Subacute Mouse Model of Parkinson's Disease.
Liang Y, Chen C, Xia B, Wu W, Tang J, Chen Q, Tang L, Yang H, Zhang Z, Lu Y, Yang Y, Zhao Y
BioMed research international 2019;2019:4379639
BioMed research international 2019;2019:4379639
Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1).
Zhang C, Wang B, Wang X, Sheng X, Cui Y
Cancer cell international 2019;19:339
Cancer cell international 2019;19:339
(-)-Epigallocatechin-3-gallate derivatives combined with cisplatin exhibit synergistic inhibitory effects on non-small-cell lung cancer cells.
Wang J, Sun P, Wang Q, Zhang P, Wang Y, Zi C, Wang X, Sheng J
Cancer cell international 2019;19:266
Cancer cell international 2019;19:266
Long-Term Effects of Zinc Deficiency and Zinc Supplementation on Developmental Seizure-Induced Brain Damage and the Underlying GPR39/ZnT-3 and MBP Expression in the Hippocampus.
Chen NN, Zhao DJ, Sun YX, Wang DD, Ni H
Frontiers in neuroscience 2019;13:920
Frontiers in neuroscience 2019;13:920
Catalpol prevents denervated muscular atrophy related to the inhibition of autophagy and reduces BAX/BCL2 ratio via mTOR pathway.
Wang Y, Shao Y, Gao Y, Wan G, Wan D, Zhu H, Qiu Y, Ye X
Drug design, development and therapy 2019;13:243-253
Drug design, development and therapy 2019;13:243-253
Lipoxin A4 Regulates Lipopolysaccharide-Induced BV2 Microglial Activation and Differentiation via the Notch Signaling Pathway.
Wu J, Ding DH, Li QQ, Wang XY, Sun YY, Li LJ
Frontiers in cellular neuroscience 2019;13:19
Frontiers in cellular neuroscience 2019;13:19
Protein kinase C-iota-mediated glycolysis promotes non-small-cell lung cancer progression.
Liu L, Lei B, Wang L, Chang C, Yang H, Liu J, Huang G, Xie W
OncoTargets and therapy 2019;12:5835-5848
OncoTargets and therapy 2019;12:5835-5848
LXRα Promotes the Differentiation of Human Gastric Cancer Cells through Inactivation of Wnt/β-catenin Signaling.
Gao Y, Chen Z, Wang R, Tan X, Huang C, Chen G, Chen Z
Journal of Cancer 2019;10(1):156-167
Journal of Cancer 2019;10(1):156-167
A Comparative Peptidomic Characterization of Cultured Skeletal Muscle Tissues Derived From db/db Mice.
Wu Y, Han M, Wang Y, Gao Y, Cui X, Xu P, Ji C, Zhong T, You L, Zeng Y
Frontiers in endocrinology 2019;10:741
Frontiers in endocrinology 2019;10:741
TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease.
Wang Y, Zhu X, Yuan S, Wen S, Liu X, Wang C, Qu Z, Li J, Liu H, Sun L, Liu F
Frontiers in endocrinology 2019;10:603
Frontiers in endocrinology 2019;10:603
An improved Tet-on system in microRNA overexpression and CRISPR/Cas9-mediated gene editing.
Kang K, Huang L, Li Q, Liao X, Dang Q, Yang Y, Luo J, Zeng Y, Li L, Gou D
Journal of animal science and biotechnology 2019;10:43
Journal of animal science and biotechnology 2019;10:43
Anti-TGEV Miller Strain Infection Effect of Lactobacillus plantarum Supernatant Based on the JAK-STAT1 Signaling Pathway.
Wang K, Ran L, Yan T, Niu Z, Kan Z, Zhang Y, Yang Y, Xie L, Huang S, Yu Q, Wu D, Song Z
Frontiers in microbiology 2019;10:2540
Frontiers in microbiology 2019;10:2540
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
Wang Y, Zhao S, Chen Y, Wang T, Dong C, Wo X, Zhang J, Dong Y, Xu W, Feng X, Qu C, Wang Y, Zhong Z, Zhao W
Frontiers in microbiology 2019;10:1633
Frontiers in microbiology 2019;10:1633
Integrating yeast chemical genomics and mammalian cell pathway analysis.
Zhou FL, Li SC, Zhu Y, Guo WJ, Shao LJ, Nelson J, Simpkins S, Yang DH, Liu Q, Yashiroda Y, Xu JB, Fan YY, Yue JM, Yoshida M, Xia T, Myers CL, Boone C, Wang MW
Acta pharmacologica Sinica 2019 Sep;40(9):1245-1255
Acta pharmacologica Sinica 2019 Sep;40(9):1245-1255
Sorafenib kills liver cancer cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids via the ATP-AMPK-mTOR-SREBP1 signaling pathway.
Liu G, Kuang S, Cao R, Wang J, Peng Q, Sun C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10089-10103
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10089-10103
The oncogenic role of CB2 in the progression of non-small-cell lung cancer.
Xu S, Ma H, Bo Y, Shao M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109080
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109080
Exosomal transfer of miR-501 confers doxorubicin resistance and tumorigenesis via targeting of BLID in gastric cancer.
Liu X, Lu Y, Xu Y, Hou S, Huang J, Wang B, Zhao J, Xia S, Fan S, Yu X, Du Y, Hou L, Li Z, Ding Z, An S, Huang B, Li L, Tang J, Ju J, Guan H, Song B
Cancer letters 2019 Sep 10;459:122-134
Cancer letters 2019 Sep 10;459:122-134
USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway.
Sun H, Ou B, Zhao S, Liu X, Song L, Liu X, Wang R, Peng Z
EBioMedicine 2019 Oct;48:236-247
EBioMedicine 2019 Oct;48:236-247
Deregulated lncRNA expression profile in the mouse lung adenocarcinomas with KRAS-G12D mutation and P53 knockout.
Zhang M, Jiang N, Cui R, Du S, Ou H, Chen T, Ge R, Ma D, Zhang J
Journal of cellular and molecular medicine 2019 Oct;23(10):6978-6988
Journal of cellular and molecular medicine 2019 Oct;23(10):6978-6988
Developmental nicotine exposure elicits multigenerational disequilibria in proBDNF proteolysis and glucocorticoid signaling in the frontal cortices, striata, and hippocampi of adolescent mice.
Buck JM, O'Neill HC, Stitzel JA
Biochemical pharmacology 2019 Oct;168:438-451
Biochemical pharmacology 2019 Oct;168:438-451
Oxidation derivative of (-)-epigallocatechin-3-gallate (EGCG) inhibits RANKL-induced osteoclastogenesis by suppressing RANK signaling pathways in RAW 264.7 cells.
Xu H, Liu T, Li J, Xu J, Chen F, Hu L, Zhang B, Zi C, Wang X, Sheng J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109237
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109237
HIF-1α contributes to Ang II-induced inflammatory cytokine production in podocytes.
Huang H, Fan Y, Gao Z, Wang W, Shao N, Zhang L, Yang Y, Zhu W, Chen Z, Hu J, Ding G
BMC pharmacology & toxicology 2019 Oct 17;20(1):59
BMC pharmacology & toxicology 2019 Oct 17;20(1):59
The CRISPR-Cas13a Gene-Editing System Induces Collateral Cleavage of RNA in Glioma Cells.
Wang Q, Liu X, Zhou J, Yang C, Wang G, Tan Y, Wu Y, Zhang S, Yi K, Kang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2019 Oct 16;6(20):1901299
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2019 Oct 16;6(20):1901299
An LTR retrotransposon-derived lncRNA interacts with RNF169 to promote homologous recombination.
Deng B, Xu W, Wang Z, Liu C, Lin P, Li B, Huang Q, Yang J, Zhou H, Qu L
EMBO reports 2019 Nov 5;20(11):e47650
EMBO reports 2019 Nov 5;20(11):e47650
Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury.
Mo D, Tian W, Zhang HN, Feng YD, Sun Y, Quan W, Hao XW, Wang XY, Liu XX, Li C, Cao W, Liu WJ, Li XQ
European journal of pharmacology 2019 Nov 15;863:172701
European journal of pharmacology 2019 Nov 15;863:172701
Astaxanthin inhibits proliferation and induces apoptosis of LX‑2 cells by regulating the miR‑29b/Bcl‑2 pathway.
Zhu S, Wang T, Luo F, Li H, Jia Q, He T, Wu H, Zou T
Molecular medicine reports 2019 May;19(5):3537-3547
Molecular medicine reports 2019 May;19(5):3537-3547
Sirt2 epigenetically down-regulates PDGFRα expression and promotes CG4 cell differentiation.
Fang N, Cheng J, Zhang C, Chen K, Zhang C, Hu Z, Bi R, Furber KL, Thangaraj M, Nazarali AJ, Ji S
Cell cycle (Georgetown, Tex.) 2019 May;18(10):1095-1109
Cell cycle (Georgetown, Tex.) 2019 May;18(10):1095-1109
Casp8 hypomethylation and neural tube defects in association with polycyclic aromatic hydrocarbon exposure.
Huang Y, Ren A, Wang L, Jin L, Lin S, Li Z, McDonald JA
Clinical epigenetics 2019 May 7;11(1):72
Clinical epigenetics 2019 May 7;11(1):72
The protective effects of XH-105 against radiation-induced intestinal injury.
Cheng Y, Dong Y, Hou Q, Wu J, Zhang W, Tian H, Li D
Journal of cellular and molecular medicine 2019 Mar;23(3):2238-2247
Journal of cellular and molecular medicine 2019 Mar;23(3):2238-2247
Leonurine promotes neurite outgrowth and neurotrophic activity by modulating the GR/SGK1 signaling pathway in cultured PC12 cells.
Meng P, Zhu Q, Yang H, Liu D, Lin X, Liu J, Fan J, Liu X, Su W, Liu L, Wang Y, Cai X
Neuroreport 2019 Mar 6;30(4):247-254
Neuroreport 2019 Mar 6;30(4):247-254
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Shah SZA, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, Mangi MH, Wu W, Lai M, Zhang X, Duan Y, Wang L, Zhou X, Yang L
International journal of molecular sciences 2019 Mar 6;20(5)
International journal of molecular sciences 2019 Mar 6;20(5)
Long noncoding RNA CCAT2 promotes hepatocellular carcinoma proliferation and metastasis through up-regulation of NDRG1.
Liu Y, Wang D, Li Y, Yan S, Dang H, Yue H, Ling J, Chen F, Zhao Y, Gou L, Tang P, Huang A, Tang H
Experimental cell research 2019 Jun 1;379(1):19-29
Experimental cell research 2019 Jun 1;379(1):19-29
Role of Nkx2.5 in H(2)O(2)-induced Nsd1 suppression.
Liang X, Chu G, Wang L, Lai G, Zhao Y
Cell stress & chaperones 2019 Jul;24(4):697-707
Cell stress & chaperones 2019 Jul;24(4):697-707
Long-term pulmonary exposure to multi-walled carbon nanotubes promotes breast cancer metastatic cascades.
Lu X, Zhu Y, Bai R, Wu Z, Qian W, Yang L, Cai R, Yan H, Li T, Pandey V, Liu Y, Lobie PE, Chen C, Zhu T
Nature nanotechnology 2019 Jul;14(7):719-727
Nature nanotechnology 2019 Jul;14(7):719-727
Aloperine suppresses human pulmonary vascular smooth muscle cell proliferation via inhibiting inflammatory response.
Chang Z, Zhang P, Zhang M, Jun F, Hu Z, Yang J, Wu Y, Zhou R
The Chinese journal of physiology 2019 Jul-Aug;62(4):157-165
The Chinese journal of physiology 2019 Jul-Aug;62(4):157-165
PMP22 Regulates Cholesterol Trafficking and ABCA1-Mediated Cholesterol Efflux.
Zhou Y, Miles JR, Tavori H, Lin M, Khoshbouei H, Borchelt DR, Bazick H, Landreth GE, Lee S, Fazio S, Notterpek L
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Jul 3;39(27):5404-5418
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Jul 3;39(27):5404-5418
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
Yang Y, Chen S, Tao L, Gan S, Luo H, Xu Y, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 20;25:5375-5388
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 20;25:5375-5388
Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats.
Ying X, Tu W, Li S, Wu Q, Chen X, Zhou Y, Hu J, Yang G, Jiang S
Life sciences 2019 Jul 15;229:187-199
Life sciences 2019 Jul 15;229:187-199
YAP mediates the positive regulation of hnRNPK on the lung adenocarcinoma H1299 cell growth.
Xu L, Zhang T, Huang W, Liu X, Lu J, Gao X, Zhang YF, Liu L
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):677-687
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):677-687
Involvement of the microglial NLRP3 inflammasome in the anti-inflammatory effect of the antidepressant clomipramine.
Gong W, Zhang S, Zong Y, Halim M, Ren Z, Wang Y, Ma Y, Li B, Ma L, Zhou G, Yu J, Zhang J, Liu Q
Journal of affective disorders 2019 Jul 1;254:15-25
Journal of affective disorders 2019 Jul 1;254:15-25
S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA2 phosphorylation.
Cao C, Dai L, Mu J, Wang X, Hong Y, Zhu C, Jin L, Li S
Cellular signalling 2019 Jan;53:151-161
Cellular signalling 2019 Jan;53:151-161
Matrix Metalloproteases-Mediated Cleavage on β-Dystroglycan May Play a Key Role in the Blood-Brain Barrier After Intracerebral Hemorrhage in Rats.
Zhang X, Gu Y, Li P, Jiang A, Sheng X, Jin X, Shi Y, Li G
Medical science monitor : international medical journal of experimental and clinical research 2019 Jan 28;25:794-800
Medical science monitor : international medical journal of experimental and clinical research 2019 Jan 28;25:794-800
Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells.
Shi H, Wang XL, Quan HF, Yan L, Pei XY, Wang R, Peng XD
Molecules (Basel, Switzerland) 2019 Jan 21;24(2)
Molecules (Basel, Switzerland) 2019 Jan 21;24(2)
KIAA1199 promotes metastasis of colorectal cancer cells via microtubule destabilization regulated by a PP2A/stathmin pathway.
Zhao L, Zhang D, Shen Q, Jin M, Lin Z, Ma H, Huang S, Zhou P, Wu G, Zhang T
Oncogene 2019 Feb;38(7):935-949
Oncogene 2019 Feb;38(7):935-949
Echinacoside protects against MPTP/MPP+-induced neurotoxicity via regulating autophagy pathway mediated by Sirt1.
Chen C, Xia B, Tang L, Wu W, Tang J, Liang Y, Yang H, Zhang Z, Lu Y, Chen G, Yang Y, Zhao Y
Metabolic brain disease 2019 Feb;34(1):203-212
Metabolic brain disease 2019 Feb;34(1):203-212
Activation of brain endothelium by Escherichia coli K1 virulence factor cglD promotes polymorphonuclear leukocyte transendothelial migration.
Zhang K, Shi MJ, Niu Z, Chen X, Wei JY, Miao ZW, Zhao WD, Chen YH
Medical microbiology and immunology 2019 Feb;208(1):59-68
Medical microbiology and immunology 2019 Feb;208(1):59-68
Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates.
Chen Z, Wang C, Li TF, Li K, Yue Y, Liu X, Xu HZ, Wen Y, Zhang Q, Han M, Komatsu N, Xu YH, Zhao L, Chen X
Nanomedicine (London, England) 2019 Feb;14(3):335-351
Nanomedicine (London, England) 2019 Feb;14(3):335-351
Structural and functional damage to the hippocampal neurovascular unit in diabetes-related depression.
Liu J, Wang YH, Li W, Liu L, Yang H, Meng P, Han YS
Neural regeneration research 2019 Feb;14(2):289-297
Neural regeneration research 2019 Feb;14(2):289-297
Exosomes from human adipose-derived stem cells promote sciatic nerve regeneration via optimizing Schwann cell function.
Chen J, Ren S, Duscher D, Kang Y, Liu Y, Wang C, Yuan M, Guo G, Xiong H, Zhan P, Wang Y, Machens HG, Chen Z
Journal of cellular physiology 2019 Dec;234(12):23097-23110
Journal of cellular physiology 2019 Dec;234(12):23097-23110
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Jiang YP, Yang JM, Ye RJ, Liu N, Zhang WJ, Ma L, Zheng P, Niu JG, Liu P, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Water-separated part of Chloranthus serratus alleviates lipopolysaccharide- induced RAW264.7 cell injury mainly by regulating the MAPK and Nrf2/HO-1 inflammatory pathways.
Sun S, Du Y, Yin C, Suo X, Wang R, Xia R, Zhang X
BMC complementary and alternative medicine 2019 Dec 2;19(1):343
BMC complementary and alternative medicine 2019 Dec 2;19(1):343
Hypoxic postconditioning activates the Wnt/β-catenin pathway and protects against transient global cerebral ischemia through Dkk1 Inhibition and GSK-3β inactivation.
Zhan L, Liu D, Wen H, Hu J, Pang T, Sun W, Xu E
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9291-9307
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9291-9307
Inhibition of dendritic spine extension through acrolein conjugation with α-, β-tubulin proteins.
Uemura T, Suzuki T, Ko K, Watanabe K, Dohmae N, Sakamoto A, Terui Y, Toida T, Kashiwagi K, Igarashi K
The international journal of biochemistry & cell biology 2019 Aug;113:58-66
The international journal of biochemistry & cell biology 2019 Aug;113:58-66
Crocin induces anti-ischemia in middle cerebral artery occlusion rats and inhibits autophagy by regulating the mammalian target of rapamycin.
Huang Z, Xu J, Huang X, Sun G, Jiang R, Wu H, Shan X, Bao K, Wu Q, Wu H, Tao W
European journal of pharmacology 2019 Aug 15;857:172424
European journal of pharmacology 2019 Aug 15;857:172424
RMI1 contributes to DNA repair and to the tolerance to camptothecin.
Fang L, Sun X, Wang Y, Du L, Ji K, Wang J, He N, Liu Y, Wang Q, Zhai H, Hao J, Xu C, Liu Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Apr;33(4):5561-5570
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Apr;33(4):5561-5570
EIF4A2 interacts with the membrane protein of transmissible gastroenteritis coronavirus and plays a role in virus replication.
Song Z, Yang Y, Wang L, Wang K, Ran L, Xie Y, Huang L, Yang Z, Yuan P, Yu Q
Research in veterinary science 2019 Apr;123:39-46
Research in veterinary science 2019 Apr;123:39-46
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
Qin Z, Xiang C, Zhong F, Liu Y, Dong Q, Li K, Shi W, Ding C, Qin L, He F
Journal of experimental & clinical cancer research : CR 2019 Apr 11;38(1):154
Journal of experimental & clinical cancer research : CR 2019 Apr 11;38(1):154
NKX2-2 Suppresses Osteosarcoma Metastasis and Proliferation by Downregulating Multiple Target Genes.
Chen H, Liu W, Zhong L, Liao D, Zhang R, Kang T, Wu Y
Journal of Cancer 2018;9(17):3067-3077
Journal of Cancer 2018;9(17):3067-3077
Caffeine Promotes Conversion of Palmitic Acid to Palmitoleic Acid by Inducing Expression of fat-5 in Caenorhabditis elegans and scd1 in Mice.
Du X, Huang Q, Guan Y, Lv M, He X, Fang C, Wang X, Sheng J
Frontiers in pharmacology 2018;9:321
Frontiers in pharmacology 2018;9:321
EGFR as a Negative Regulatory Protein Adjusts the Activity and Mobility of NHE3 in the Cell Membrane of IPEC-J2 Cells With TGEV Infection.
Yang Z, Ran L, Yuan P, Yang Y, Wang K, Xie L, Huang S, Liu J, Song Z
Frontiers in microbiology 2018;9:2734
Frontiers in microbiology 2018;9:2734
Involvement of NMDA-AKT-mTOR Signaling in Rapid Antidepressant-Like Activity of Chaihu-jia-Longgu-Muli-tang on Olfactory Bulbectomized Mice.
Wang X, Zou Z, Shen Q, Huang Z, Chen J, Tang J, Xue W, Tao W, Wu H, Wang D, Chen G
Frontiers in pharmacology 2018;9:1537
Frontiers in pharmacology 2018;9:1537
Effect of Black Tea Extract and Thearubigins on Osteoporosis in Rats and Osteoclast Formation in vitro.
Liang Q, Lv M, Zhang X, Hu J, Wu Y, Huang Y, Wang X, Sheng J
Frontiers in physiology 2018;9:1225
Frontiers in physiology 2018;9:1225
Phosphorylation of IRS4 by CK1γ2 promotes its degradation by CHIP through the ubiquitin/lysosome pathway.
Li X, Zhong L, Wang Z, Chen H, Liao D, Zhang R, Zhang H, Kang T
Theranostics 2018;8(13):3643-3653
Theranostics 2018;8(13):3643-3653
Effect of decabrominated diphenyl ether exposure on spatial learning and memory, the expression and phosphorylation of hippocampal glutamate receptor subunits in adult Sprague-Dawley rats.
Xiong L, Liyue H, Fancai Z, Maoting L, Ya L, Ting H, Zhen Y, Shanshan Z, Wenwen G, Yan T
The Journal of toxicological sciences 2018;43(11):645-657
The Journal of toxicological sciences 2018;43(11):645-657
iTRAQ-Based Proteomics Analysis Reveals the Effect of Rhubarb in Rats with Ischemic Stroke.
Lin X, Liu T, Li P, He Z, Zhong Y, Cui H, Luo J, Wang Y, Tang T
BioMed research international 2018;2018:6920213
BioMed research international 2018;2018:6920213
The Protective Effect of New Compound XH-103 on Radiation-Induced GI Syndrome.
Dong Y, Cheng Y, Hou Q, Wu J, Li D, Tian H
Oxidative medicine and cellular longevity 2018;2018:3920147
Oxidative medicine and cellular longevity 2018;2018:3920147
PAX2 may induce ADAM10 expression in renal tubular epithelial cells and contribute to epithelial-to-mesenchymal transition.
Hou L, Du Y, Zhao C, Wu Y
International urology and nephrology 2018 Sep;50(9):1729-1741
International urology and nephrology 2018 Sep;50(9):1729-1741
Rapid induction of apoptosis in tumor cells treated with a new platinum(II) complex based on amino-thiazolidinone.
Song XQ, Liu YH, Shao J, Zhang ZL, Xie CZ, Qiao X, Bao WG, Xu JY
European journal of medicinal chemistry 2018 Sep 5;157:188-197
European journal of medicinal chemistry 2018 Sep 5;157:188-197
Theabrownin suppresses in vitro osteoclastogenesis and prevents bone loss in ovariectomized rats.
Liu T, Xiang Z, Chen F, Yin D, Huang Y, Xu J, Hu L, Xu H, Wang X, Sheng J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1339-1347
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1339-1347
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Wang C, Luo H, Xu Y, Tao L, Chang C, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
Apolipoprotein E deficiency accelerates atherosclerosis development in miniature pigs.
Fang B, Ren X, Wang Y, Li Z, Zhao L, Zhang M, Li C, Zhang Z, Chen L, Li X, Liu J, Xiong Q, Zhang L, Jin Y, Liu X, Li L, Wei H, Yang H, Li R, Dai Y
Disease models & mechanisms 2018 Oct 10;11(10)
Disease models & mechanisms 2018 Oct 10;11(10)
Temporal Proteomic Analysis of Pancreatic β-Cells in Response to Lipotoxicity and Glucolipotoxicity.
Li Z, Liu H, Niu Z, Zhong W, Xue M, Wang J, Yang F, Zhou Y, Zhou Y, Xu T, Hou J
Molecular & cellular proteomics : MCP 2018 Nov;17(11):2119-2131
Molecular & cellular proteomics : MCP 2018 Nov;17(11):2119-2131
Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells.
Tian T, Sun J, Wang J, Liu Y, Liu H
Oncology letters 2018 Nov;16(5):6133-6139
Oncology letters 2018 Nov;16(5):6133-6139
Horizontal transfer of exosomal CXCR4 promotes murine hepatocarcinoma cell migration, invasion and lymphangiogenesis.
Li M, Lu Y, Xu Y, Wang J, Zhang C, Du Y, Wang L, Li L, Wang B, Shen J, Tang J, Song B
Gene 2018 Nov 15;676:101-109
Gene 2018 Nov 15;676:101-109
KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.
Zhu ZC, Liu JW, Li K, Zheng J, Xiong ZQ
Oncogene 2018 May;37(22):2936-2952
Oncogene 2018 May;37(22):2936-2952
The ubiquitin-specific protease USP8 deubiquitinates and stabilizes Cx43.
Sun J, Hu Q, Peng H, Peng C, Zhou L, Lu J, Huang C
The Journal of biological chemistry 2018 May 25;293(21):8275-8284
The Journal of biological chemistry 2018 May 25;293(21):8275-8284
PMN inhibits colorectal cancer cells through inducing mitotic arrest and p53-dependent apoptosis via the inhibition of tubulin polymerization.
Wu X, Shen Y
Biochemical and biophysical research communications 2018 May 23;499(4):927-933
Biochemical and biophysical research communications 2018 May 23;499(4):927-933
Met is involved in TIGAR-regulated metastasis of non-small-cell lung cancer.
Shen M, Zhao X, Zhao L, Shi L, An S, Huang G, Liu J
Molecular cancer 2018 May 12;17(1):88
Molecular cancer 2018 May 12;17(1):88
Combined treatment with Dendrobium candidum and black tea extract promotes osteoprotective activity in ovariectomized estrogen deficient rats and osteoclast formation.
Wang MY, Shen C, An MF, Xie CQ, Wu X, Zhu QQ, Sun B, Huang YP, Zhao YL, Wang XJ, Sheng J
Life sciences 2018 May 1;200:31-41
Life sciences 2018 May 1;200:31-41
CCAAT/enhancer-binding protein β overexpression alleviates myocardial remodelling by regulating angiotensin-converting enzyme-2 expression in diabetes.
Tie Y, Zhai C, Zhang Y, Qin X, Yu F, Li H, Shan M, Zhang C
Journal of cellular and molecular medicine 2018 Mar;22(3):1475-1488
Journal of cellular and molecular medicine 2018 Mar;22(3):1475-1488
PTEN-L promotes type I interferon responses and antiviral immunity.
Cao Y, Wang H, Yang L, Zhang Z, Li C, Yuan X, Bu L, Chen L, Chen Y, Li CM, Guo D
Cellular & molecular immunology 2018 Jan;15(1):48-57
Cellular & molecular immunology 2018 Jan;15(1):48-57
Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex.
Li Y, Wang L, Zhang X, Huang M, Li S, Wang X, Chen L, Jiang B, Yang Y
Neuropharmacology 2018 Jan;128:207-220
Neuropharmacology 2018 Jan;128:207-220
Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production.
Huang Y, Hua M, Cui X
Inflammation 2018 Feb;41(1):164-173
Inflammation 2018 Feb;41(1):164-173
Synergistic neuroprotective effect of rasagiline and idebenone against retinal ischemia-reperfusion injury via the Lin28-let-7-Dicer pathway.
Lei D, Shao Z, Zhou X, Yuan H
Oncotarget 2018 Feb 23;9(15):12137-12153
Oncotarget 2018 Feb 23;9(15):12137-12153
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
Wang B, Zhang G, Yang M, Liu N, Li YX, Ma H, Ma L, Sun T, Tan H, Yu J
Neurochemical research 2018 Dec;43(12):2404-2422
Neurochemical research 2018 Dec;43(12):2404-2422
The antidepressant effects of ɑ-tocopherol are related to activation of autophagy via the AMPK/mTOR pathway.
Huang X, Wu H, Jiang R, Sun G, Shen J, Ma M, Ma C, Zhang S, Huang Z, Wu Q, Chen G, Tao W
European journal of pharmacology 2018 Aug 15;833:1-7
European journal of pharmacology 2018 Aug 15;833:1-7
Pu-erh Tea Extract Ameliorates Ovariectomy-Induced Osteoporosis in Rats and Suppresses Osteoclastogenesis In Vitro.
Liu T, Ding S, Yin D, Cuan X, Xie C, Xu H, Wang X, Sheng J
Frontiers in pharmacology 2017;8:324
Frontiers in pharmacology 2017;8:324
Role of the Ubiquitin C-Terminal Hydrolase L1-Modulated Ubiquitin Proteasome System in Auditory Cortex Senescence.
Zhang Y, Huang X, Zhao XY, Hu YJ, Sun HY, Kong WJ
ORL; journal for oto-rhino-laryngology and its related specialties 2017;79(3):153-163
ORL; journal for oto-rhino-laryngology and its related specialties 2017;79(3):153-163
Neural Plasticity Associated with Hippocampal PKA-CREB and NMDA Signaling Is Involved in the Antidepressant Effect of Repeated Low Dose of Yueju Pill on Chronic Mouse Model of Learned Helplessness.
Zou Z, Chen Y, Shen Q, Guo X, Zhang Y, Chen G
Neural plasticity 2017;2017:9160515
Neural plasticity 2017;2017:9160515
Tail Nerve Electrical Stimulation and Electro-Acupuncture Can Protect Spinal Motor Neurons and Alleviate Muscle Atrophy after Spinal Cord Transection in Rats.
Zhang YT, Jin H, Wang JH, Wen LY, Yang Y, Ruan JW, Zhang SX, Ling EA, Ding Y, Zeng YS
Neural plasticity 2017;2017:7351238
Neural plasticity 2017;2017:7351238
Regulatory Axis of miR-195/497 and HMGA1-Id3 Governs Muscle Cell Proliferation and Differentiation.
Qiu H, Zhong J, Luo L, Tang Z, Liu N, Kang K, Li L, Gou D
International journal of biological sciences 2017;13(2):157-166
International journal of biological sciences 2017;13(2):157-166
2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid, a glutathione reductase inhibitor, induces G2/M cell cycle arrest through generation of thiol oxidative stress in human esophageal cancer cells.
Li X, Jiang Z, Feng J, Zhang X, Wu J, Chen W
Oncotarget 2017 Sep 22;8(37):61846-61860
Oncotarget 2017 Sep 22;8(37):61846-61860
Nrf2 Promotes Keratinocyte Proliferation in Psoriasis through Up-Regulation of Keratin 6, Keratin 16, and Keratin 17.
Yang L, Fan X, Cui T, Dang E, Wang G
The Journal of investigative dermatology 2017 Oct;137(10):2168-2176
The Journal of investigative dermatology 2017 Oct;137(10):2168-2176
Synthesis of β-tubulin occurs within chromatoid body of round spermatids.
Fujii Y, Fujita H, Yokota S
Cytoskeleton (Hoboken, N.J.) 2017 May;74(5):197-204
Cytoskeleton (Hoboken, N.J.) 2017 May;74(5):197-204
PRAS40 alleviates neurotoxic prion peptide-induced apoptosis via mTOR-AKT signaling.
Yang W, Yang LF, Song ZQ, Shah SZA, Cui YY, Li CS, Zhao HF, Gao HL, Zhou XM, Zhao DM
CNS neuroscience & therapeutics 2017 May;23(5):416-427
CNS neuroscience & therapeutics 2017 May;23(5):416-427
High expression of ubiquitin-specific peptidase 39 is associated with the development of vascular remodeling.
He S, Zhong W, Yin L, Wang Y, Qiu Z, Song G
Molecular medicine reports 2017 May;15(5):2567-2573
Molecular medicine reports 2017 May;15(5):2567-2573
Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages.
Fang W, Bi D, Zheng R, Cai N, Xu H, Zhou R, Lu J, Wan M, Xu X
Scientific reports 2017 May 10;7(1):1663
Scientific reports 2017 May 10;7(1):1663
MicroRNA-17-92 Regulates the Transcription Factor E2F3b during Myogenesis In Vitro and In Vivo.
Tang Z, Liu N, Luo L, Kang K, Li L, Ni R, Qiu H, Gou D
International journal of molecular sciences 2017 Mar 31;18(4)
International journal of molecular sciences 2017 Mar 31;18(4)
CBX3 promotes colon cancer cell proliferation by CDK6 kinase-independent function during cell cycle.
Fan Y, Li H, Liang X, Xiang Z
Oncotarget 2017 Mar 21;8(12):19934-19946
Oncotarget 2017 Mar 21;8(12):19934-19946
cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases.
Wang L, Lai G, Chu G, Liang X, Zhao Y
Experimental cell research 2017 Jun 1;355(1):18-25
Experimental cell research 2017 Jun 1;355(1):18-25
ERK1/2-mediated Cytoplasmic Accumulation of hnRNPK Antagonizes TRAIL-induced Apoptosis through Upregulation of XIAP in H1299 Cells.
Huang WS, Xu FM, Zeng QZ, Liu XH, Gao XJ, Liu LX
Biomedical and environmental sciences : BES 2017 Jul;30(7):473-481
Biomedical and environmental sciences : BES 2017 Jul;30(7):473-481
Abl2 kinase phosphorylates Bi-organellar regulator MNRR1 in mitochondria, stimulating respiration.
Aras S, Arrabi H, Purandare N, Hüttemann M, Kamholz J, Züchner S, Grossman LI
Biochimica et biophysica acta. Molecular cell research 2017 Feb;1864(2):440-448
Biochimica et biophysica acta. Molecular cell research 2017 Feb;1864(2):440-448
miR-34b Modulates Skeletal Muscle Cell Proliferation and Differentiation.
Tang Z, Qiu H, Luo L, Liu N, Zhong J, Kang K, Gou D
Journal of cellular biochemistry 2017 Dec;118(12):4285-4295
Journal of cellular biochemistry 2017 Dec;118(12):4285-4295
Alginate enhances Toll-like receptor 4-mediated phagocytosis by murine RAW264.7 macrophages.
Bi D, Zhou R, Cai N, Lai Q, Han Q, Peng Y, Jiang Z, Tang Z, Lu J, Bao W, Xu H, Xu X
International journal of biological macromolecules 2017 Dec;105(Pt 2):1446-1454
International journal of biological macromolecules 2017 Dec;105(Pt 2):1446-1454
Knockdown of RMI1 impairs DNA repair under DNA replication stress.
Xu C, Fang L, Kong Y, Xiao C, Yang M, Du LQ, Liu Q
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):158-164
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):158-164
Overexpression of DBC1, correlated with poor prognosis, is a potential therapeutic target for hepatocellular carcinoma.
Li C, Liao J, Wu S, Fan J, Peng Z, Wang Z
Biochemical and biophysical research communications 2017 Dec 16;494(3-4):511-517
Biochemical and biophysical research communications 2017 Dec 16;494(3-4):511-517
LL-37-induced human mast cell activation through G protein-coupled receptor MrgX2.
Yu Y, Zhang Y, Zhang Y, Lai Y, Chen W, Xiao Z, Zhang W, Jin M, Yu B
International immunopharmacology 2017 Aug;49:6-12
International immunopharmacology 2017 Aug;49:6-12
The mechanically activated p38/MMP-2 signaling pathway promotes bone marrow mesenchymal stem cell migration in rats.
Yang Z, Wu B, Jia S, Zhao Y, Hou R, Liu X, Wang X, Chen L, Yang X, Lei D, Wang L
Archives of oral biology 2017 Apr;76:55-60
Archives of oral biology 2017 Apr;76:55-60
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
Shah SZA, Zhao D, Taglialatela G, Khan SH, Hussain T, Dong H, Lai M, Zhou X, Yang L
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483
The DEAD-Box RNA Helicase DDX3 Interacts with NF-κB Subunit p65 and Suppresses p65-Mediated Transcription.
Xiang N, He M, Ishaq M, Gao Y, Song F, Guo L, Ma L, Sun G, Liu D, Guo D, Chen Y
PloS one 2016;11(10):e0164471
PloS one 2016;11(10):e0164471
Six2 Is a Coordinator of LiCl-Induced Cell Proliferation and Apoptosis.
Liu J, Ju P, Zhou Y, Zhao Y, Xie Y, Long Y, Gu Y, Ni D, Lyv Z, Mao Z, Hao J, Li Y, Wan Q, Kanyomse Q, Liu Y, Xiang Y, Wang R, Chen X, Zhang J, Liu X, Zhao H, Zhou Q, Li G
International journal of molecular sciences 2016 Sep 8;17(9)
International journal of molecular sciences 2016 Sep 8;17(9)
MicroRNA-378 Alleviates Cerebral Ischemic Injury by Negatively Regulating Apoptosis Executioner Caspase-3.
Zhang N, Zhong J, Han S, Li Y, Yin Y, Li J
International journal of molecular sciences 2016 Sep 2;17(9)
International journal of molecular sciences 2016 Sep 2;17(9)
Up-regulation of miR-95-3p in hepatocellular carcinoma promotes tumorigenesis by targeting p21 expression.
Ye J, Yao Y, Song Q, Li S, Hu Z, Yu Y, Hu C, Da X, Li H, Chen Q, Wang QK
Scientific reports 2016 Oct 4;6:34034
Scientific reports 2016 Oct 4;6:34034
Senkyunolide I attenuates oxygen-glucose deprivation/reoxygenation-induced inflammation in microglial cells.
Hu YY, Wang Y, Liang S, Yu XL, Zhang L, Feng LY, Feng Y
Brain research 2016 Oct 15;1649(Pt A):123-131
Brain research 2016 Oct 15;1649(Pt A):123-131
Conventional protein kinase Cβ-mediated phosphorylation inhibits collapsin response-mediated protein 2 proteolysis and alleviates ischemic injury in cultured cortical neurons and ischemic stroke-induced mice.
Yang X, Zhang X, Li Y, Han S, Howells DW, Li S, Li J
Journal of neurochemistry 2016 May;137(3):446-59
Journal of neurochemistry 2016 May;137(3):446-59
The tumor suppressor PTEN has a critical role in antiviral innate immunity.
Li S, Zhu M, Pan R, Fang T, Cao YY, Chen S, Zhao X, Lei CQ, Guo L, Chen Y, Li CM, Jokitalo E, Yin Y, Shu HB, Guo D
Nature immunology 2016 Mar;17(3):241-9
Nature immunology 2016 Mar;17(3):241-9
Hen egg white ovomacroglobulin promotes fibroblast migration via mediating cell adhesion and cytoskeleton.
Geng F, Huang X, Ma M
Journal of the science of food and agriculture 2016 Jul;96(9):3188-94
Journal of the science of food and agriculture 2016 Jul;96(9):3188-94
Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.
Tao X, Sun X, Xu L, Yin L, Han X, Qi Y, Xu Y, Zhao Y, Wang C, Peng J
Nutrients 2016 Jul 8;8(7)
Nutrients 2016 Jul 8;8(7)
Tubb3 regulation by the Erk and Akt signaling pathways: a mechanism involved in the effect of arginine ADP-ribosyltransferase 1 (Art1) on apoptosis of colon carcinoma CT26 cells.
Xiao M, Tang Y, Chen WW, Wang YL, Yang L, Li X, Song GL, Kuang J
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Feb;37(2):2353-63
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Feb;37(2):2353-63
Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers.
Wilcox KC, Marunde MR, Das A, Velasco PT, Kuhns BD, Marty MT, Jiang H, Luan CH, Sligar SG, Klein WL
PloS one 2015;10(4):e0125263
PloS one 2015;10(4):e0125263
Inhibition of autophagy by 3-MA enhances IL-24-induced apoptosis in human oral squamous cell carcinoma cells.
Li J, Yang D, Wang W, Piao S, Zhou J, Saiyin W, Zheng C, Sun H, Li Y
Journal of experimental & clinical cancer research : CR 2015 Sep 11;34:97
Journal of experimental & clinical cancer research : CR 2015 Sep 11;34:97
Expression of Iodotyrosine Deiodinase in Thyroid and Other Organs in Iodine-Deficient and Iodine-Excess Rats.
Sun X, Zhang X, Jiang Y, Bao S, Shan Z, Teng W
Biological trace element research 2015 Oct;167(2):272-9
Biological trace element research 2015 Oct;167(2):272-9
Regulation of signal transducer and activator of transcription 3 and apoptotic pathways by betaine attenuates isoproterenol-induced acute myocardial injury in rats.
Zheng P, Liu J, Mai S, Yuan Y, Wang Y, Dai G
Human & experimental toxicology 2015 May;34(5):538-47
Human & experimental toxicology 2015 May;34(5):538-47
SCD1 negatively regulates autophagy-induced cell death in human hepatocellular carcinoma through inactivation of the AMPK signaling pathway.
Huang GM, Jiang QH, Cai C, Qu M, Shen W
Cancer letters 2015 Mar 28;358(2):180-190
Cancer letters 2015 Mar 28;358(2):180-190
Expression and localization of estrogen receptor in human breast cancer and its clinical significance.
Li L, Wang Q, Lv X, Sha L, Qin H, Wang L, Li L
Cell biochemistry and biophysics 2015 Jan;71(1):63-8
Cell biochemistry and biophysics 2015 Jan;71(1):63-8
Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo.
Xiao W, Jiang Y, Men Q, Yuan L, Huang Z, Liu T, Li W, Liu X
International journal of oncology 2015 Jan;46(1):360-8
International journal of oncology 2015 Jan;46(1):360-8
Quantitative proteomic study of myocardial mitochondria in urea transporter B knockout mice.
Du Y, Meng Y, Zhu J, Kang L, Jia X, Guo L, Zhang L, Ye M, Hu L, Zhao X, Gu J, Yang B, Zou H
Proteomics 2014 Sep;14(17-18):2072-83
Proteomics 2014 Sep;14(17-18):2072-83
The mechanisms of EGFR in the regulation of axon regeneration.
Xu MF, Zhou H, Hu CY, Liang YQ, Hu L, Chen D
Cell biochemistry and function 2014 Jan;32(1):101-5
Cell biochemistry and function 2014 Jan;32(1):101-5
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Mutational analysis of ErbB2 intracellular localization.
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10094-1-AP(tubulin-beta antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using 10094-1-AP and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-tubulin-beta (IP:10094-1-AP, 3ug; Detection:10094-1-AP 1:1000) with mouse brain tissue lysate 7500ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded rat brain using 10094-1-AP(tubulin-beta antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded rat brain using 10094-1-AP(tubulin-beta antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue