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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [128]
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- Validations
- Western blot [2]
- Immunocytochemistry [3]
- Immunohistochemistry [1]
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- Product number
- MAB1195 - Provider product page
- Provider
- R&D Systems
- Product name
- Neuron-specific beta-III Tubulin Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mammalian and chicken neuron-specific beta-III tubulin but not other beta-tubulin isotypes in Western blots.
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- TuJ-1
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Complementary Activity of ETV5, RBPJ, and TCF3 Drives Formative Transition from Naive Pluripotency.
Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.
Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells.
Generation of multidrug resistant human tissues by overexpression of the ABCG2 multidrug transporter in embryonic stem cells.
Regulation of neuritogenesis in hippocampal neurons using stiffness of extracellular microenvironment.
Elevated Pressure Increases Ca2+ Influx Through AMPA Receptors in Select Populations of Retinal Ganglion Cells.
Combined deficiency of Senataxin and DNA-PKcs causes DNA damage accumulation and neurodegeneration in spinal muscular atrophy.
Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells.
Ythdf2-mediated m6A mRNA clearance modulates neural development in mice.
Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement.
Nitrosative damage during retrovirus infection-induced neuropathic pain.
Control of neurite growth and guidance by an inhibitory cell-body signal.
Parkinson's disease genetic risk in a midbrain neuronal cell line.
Neurturin Gene Therapy Protects Parasympathetic Function to Prevent Irradiation-Induced Murine Salivary Gland Hypofunction.
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease.
The guanine nucleotide exchange factor Arhgef7/βPix promotes axon formation upstream of TC10.
RIP2 Gates TRAF6 Interaction with Death Receptor p75NTR to Regulate Cerebellar Granule Neuron Survival.
Multicolor quantitative confocal imaging cytometry.
Preclinical analysis of MTOR complex 1/2 inhibition in diffuse intrinsic pontine glioma.
Mitochondrial transfer from mesenchymal stem cells to neural stem cells protects against the neurotoxic effects of cisplatin.
Distribution and Neurochemistry of the Porcine Ileocaecal Valve Projecting Sensory Neurons in the Dorsal Root Ganglia and the Influence of Lipopolysaccharide from Different Serotypes of Salmonella spp. on the Chemical Coding of DRG Neurons in the Cell Cultures.
The plasticity of primary microglia and their multifaceted effects on endogenous neural stem cells in vitro and in vivo.
Characterization of calcium signals in human induced pluripotent stem cell-derived dentate gyrus neuronal progenitors and mature neurons, stably expressing an advanced calcium indicator protein.
Uncovering inherent cellular plasticity of multiciliated ependyma leading to ventricular wall transformation and hydrocephalus.
Embryonic Stem Cell-Derived Neurons Grown on Multi-Electrode Arrays as a Novel In vitro Bioassay for the Detection of Clostridium botulinum Neurotoxins.
Formation and spreading of TDP-43 aggregates in cultured neuronal and glial cells demonstrated by time-lapse imaging.
Time-Dependent, HIV-Tat-Induced Perturbation of Human Neurons In Vitro: Towards a Model for the Molecular Pathology of HIV-Associated Neurocognitive Disorders.
Molecular and Functional Properties of Regional Astrocytes in the Adult Brain.
Neuronal cells derived from human induced pluripotent stem cells as a functional tool of melanocortin system.
Alpha-synuclein facilitates to form short unconventional microtubules that have a unique function in the axonal transport.
Enforcement of developmental lineage specificity by transcription factor Oct1.
Vulnerability of primary neurons derived from Tg2576 Alzheimer mice to oxygen and glucose deprivation: role of intraneuronal amyloid-β accumulation and astrocytes.
PEGylated insulin-like growth factor-I affords protection and facilitates recovery of lost functions post-focal ischemia.
An Immortalized Human Dorsal Root Ganglion Cell Line Provides a Novel Context To Study Herpes Simplex Virus 1 Latency and Reactivation.
FGF signaling refines Wnt gradients to regulate the patterning of taste papillae.
PARP activity and inhibition in fetal and adult oligodendrocyte precursor cells: Effect on cell survival and differentiation.
IL-20 promotes epithelial healing of the injured mouse cornea.
A novel role for the DNA repair gene Rad51 in Netrin-1 signalling.
Modulated DISP3/PTCHD2 expression influences neural stem cell fate decisions.
Poly(ADP-ribose) polymerase inhibitors activate the p53 signaling pathway in neural stem/progenitor cells.
Cytosine-5 RNA Methylation Regulates Neural Stem Cell Differentiation and Motility.
FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1.
Genome Stability by DNA Polymerase β in Neural Progenitors Contributes to Neuronal Differentiation in Cortical Development.
Inhibition of Wnt/β-catenin signaling by IWR1 induces expression of Foxd3 to promote mouse epiblast stem cell self-renewal.
HDAC3 inhibition ameliorates spinal cord injury by immunomodulation.
Zeb2 is a negative regulator of midbrain dopaminergic axon growth and target innervation.
NOTCH1-Dependent Nitric Oxide Signaling Deficiency in Hypoplastic Left Heart Syndrome Revealed Through Patient-Specific Phenotypes Detected in Bioengineered Cardiogenesis.
Lineage-Specific Differentiation Is Influenced by State of Human Pluripotency.
An Activating STAT3 Mutation Causes Neonatal Diabetes through Premature Induction of Pancreatic Differentiation.
Transfer of pathogenic and nonpathogenic cytosolic proteins between spinal cord motor neurons in vivo in chimeric mice.
Repeated removal of developing limb buds permanently reduces appendage size in the highly-regenerative axolotl.
Generation of a TLE3 heterozygous knockout human embryonic stem cell line using CRISPR-Cas9.
Generation of a TLE1 homozygous knockout human embryonic stem cell line using CRISPR-Cas9.
Spinal cord injury induces astroglial conversion towards neuronal lineage.
VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination.
FGF8 and SHH substitute for anterior-posterior tissue interactions to induce limb regeneration.
Selective Deletion of Astroglial FMRP Dysregulates Glutamate Transporter GLT1 and Contributes to Fragile X Syndrome Phenotypes In Vivo.
The Severity of Infection Determines the Localization of Damage and Extent of Sensorineural Hearing Loss in Experimental Pneumococcal Meningitis.
A system for studying mechanisms of neuromuscular junction development and maintenance.
Retinoic-acid-mediated HRas stabilization induces neuronal differentiation of neural stem cells during brain development.
An Engineered N-Cadherin Substrate for Differentiation, Survival, and Selection of Pluripotent Stem Cell-Derived Neural Progenitors.
Attenuation of progressive hearing loss in DBA/2J mice by reagents that affect epigenetic modifications is associated with up-regulation of the zinc importer Zip4.
Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression.
Angiogenesis in the developing spinal cord: blood vessel exclusion from neural progenitor region is mediated by VEGF and its antagonists.
Signalling Through Retinoic Acid Receptors is Required for Reprogramming of Both Mouse Embryonic Fibroblast Cells and Epiblast Stem Cells to Induced Pluripotent Stem Cells.
Secreted ectodomain of sialic acid-binding Ig-like lectin-9 and monocyte chemoattractant protein-1 promote recovery after rat spinal cord injury by altering macrophage polarity.
A simple and robust method for establishing homogeneous mouse epiblast stem cell lines by wnt inhibition.
Activated CD8+ T lymphocytes inhibit neural stem/progenitor cell proliferation: role of interferon-gamma.
CaMKK-CaMK1a, a new post-traumatic signalling pathway induced in mouse somatosensory neurons.
Rapid and efficient conversion of integration-free human induced pluripotent stem cells to GMP-grade culture conditions.
Molecular and cellular features of murine craniofacial and trunk neural crest cells as stem cell-like cells.
Diet-induced obesity and low testosterone increase neuroinflammation and impair neural function.
Axolotls with an under- or oversupply of neural crest can regulate the sizes of their dorsal root ganglia to normal levels.
Stage-dependent requirement of neuroretinal Pax6 for lens and retina development.
Intrinsically active and pacemaker neurons in pluripotent stem cell-derived neuronal populations.
ADAM metalloproteases promote a developmental switch in responsiveness to the axonal repellant Sema3A.
Senescence impairs direct conversion of human somatic cells to neurons.
Maternal obesity and IL-6 lead to aberrant developmental gene expression and deregulated neurite growth in the fetal arcuate nucleus.
Netrin-1 controls sympathetic arterial innervation.
Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression.
Growth arrest and forced differentiation of human primary glioblastoma multiforme by a novel small molecule.
Absence of lipofuscin in motor neurons of SOD1-linked ALS mice.
Cytokine secretion from brain macrophages infected with human immunodeficiency virus in vitro and treated with raltegravir.
Influence of biological matrix and artificial electrospun scaffolds on proliferation, differentiation and trophic factor synthesis of rat embryonic stem cells.
Nogo receptor homolog NgR2 expressed in sensory DRG neurons controls epidermal innervation by interaction with Versican.
Developmental regulation of trigeminal TRPA1 by the cornea.
Molecular evidence for OCT4-induced plasticity in adult human fibroblasts required for direct cell fate conversion to lineage specific progenitors.
ERK2 suppresses self-renewal capacity of embryonic stem cells, but is not required for multi-lineage commitment.
Lamin A/C haploinsufficiency modulates the differentiation potential of mouse embryonic stem cells.
Genetic deletion of afadin causes hydrocephalus by destruction of adherens junctions in radial glial and ependymal cells in the midbrain.
Parasympathetic stimulation improves epithelial organ regeneration.
ProNGF promotes neurite growth from a subset of NGF-dependent neurons by a p75NTR-dependent mechanism.
Communication between corneal epithelial cells and trigeminal neurons is facilitated by purinergic (P2) and glutamatergic receptors.
Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embryonic stem cells from refractory mouse strains.
In vivo generation of neural tumors from neoplastic pluripotent stem cells models early human pediatric brain tumor formation.
IL-17 and VEGF are necessary for efficient corneal nerve regeneration.
Astrocyte-derived interleukin-6 promotes specific neuronal differentiation of neural progenitor cells from adult hippocampus.
Pig epiblast stem cells depend on activin/nodal signaling for pluripotency and self-renewal.
A fusion protein N-cadherin-Fc as an artificial extracellular matrix surface for maintenance of stem cell features.
Synovial sarcoma is a stem cell malignancy.
Presence of pluripotent CD133+ cells correlates with malignancy of gliomas.
Developmental corneal innervation: interactions between nerves and specialized apical corneal epithelial cells.
Metastable primordial germ cell-like state induced from mouse embryonic stem cells by Akt activation.
A defined glycosaminoglycan-binding substratum for human pluripotent stem cells.
Developmental guidance of embryonic corneal innervation: roles of Semaphorin3A and Slit2.
Tumor microvasculature supports proliferation and expansion of glioma-propagating cells.
Continuous exposure to 900MHz GSM-modulated EMF alters morphological maturation of neural cells.
Docosahexaenoic acid promotes neuronal differentiation by regulating basic helix-loop-helix transcription factors and cell cycle in neural stem cells.
Cells keep a memory of their tissue origin during axolotl limb regeneration.
Survival, neuron-like differentiation and functionality of mesenchymal stem cells in neurotoxic environment: the critical role of erythropoietin.
Reticulon RTN2B regulates trafficking and function of neuronal glutamate transporter EAAC1.
Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease.
Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells.
SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation.
Triggering neural differentiation of ES cells by subtype switching of importin-alpha.
Phosphorylated FTY720 promotes astrocyte migration through sphingosine-1-phosphate receptors.
The free-radical scavenger edaravone restores the differentiation of human neural precursor cells after radiation-induced oxidative stress.
Docosahexaenoic acid promotes neurogenesis in vitro and in vivo.
Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm.
Neurogenic effect of vascular endothelial growth factor during germ layer formation of human embryonic stem cells.
Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death.
Neural differentiation of embryonic stem cells induced by conditioned medium from neural stem cell.
Isolation of multipotent neural crest-derived stem cells from the adult mouse cornea.
Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages.
Predominant expression of GluR2 among the AMPA receptor subunits in neuronal progenitor cells of the rat hippocampus.
High-level expression of functional chemokine receptor CXCR4 on human neural precursor cells.
6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase form a supramolecular complex in human neutrophils that undergoes retrograde trafficking during pregnancy.
6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase form a supramolecular complex in human neutrophils that undergoes retrograde trafficking during pregnancy.
Kalkan T, Bornelöv S, Mulas C, Diamanti E, Lohoff T, Ralser M, Middelkamp S, Lombard P, Nichols J, Smith A
Cell stem cell 2019 May 2;24(5):785-801.e7
Cell stem cell 2019 May 2;24(5):785-801.e7
Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.
MacLeod G, Bozek DA, Rajakulendran N, Monteiro V, Ahmadi M, Steinhart Z, Kushida MM, Yu H, Coutinho FJ, Cavalli FMG, Restall I, Hao X, Hart T, Luchman HA, Weiss S, Dirks PB, Angers S
Cell reports 2019 Apr 16;27(3):971-986.e9
Cell reports 2019 Apr 16;27(3):971-986.e9
Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells.
Barnes J, Salas F, Mokhtari R, Dolstra H, Pedrosa E, Lachman HM
Molecular autism 2018;9:44
Molecular autism 2018;9:44
Generation of multidrug resistant human tissues by overexpression of the ABCG2 multidrug transporter in embryonic stem cells.
Erdei Z, Schamberger A, Török G, Szebényi K, Várady G, Orbán TI, Homolya L, Sarkadi B, Apáti Á
PloS one 2018;13(4):e0194925
PloS one 2018;13(4):e0194925
Regulation of neuritogenesis in hippocampal neurons using stiffness of extracellular microenvironment.
Tanaka A, Fujii Y, Kasai N, Okajima T, Nakashima H
PloS one 2018;13(2):e0191928
PloS one 2018;13(2):e0191928
Elevated Pressure Increases Ca2+ Influx Through AMPA Receptors in Select Populations of Retinal Ganglion Cells.
Wen X, Cahill AL, Barta C, Thoreson WB, Nawy S
Frontiers in cellular neuroscience 2018;12:162
Frontiers in cellular neuroscience 2018;12:162
Combined deficiency of Senataxin and DNA-PKcs causes DNA damage accumulation and neurodegeneration in spinal muscular atrophy.
Kannan A, Bhatia K, Branzei D, Gangwani L
Nucleic acids research 2018 Sep 19;46(16):8326-8346
Nucleic acids research 2018 Sep 19;46(16):8326-8346
Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells.
Lager AM, Corradin OG, Cregg JM, Elitt MS, Shick HE, Clayton BLL, Allan KC, Olsen HE, Madhavan M, Tesar PJ
Nature communications 2018 Sep 13;9(1):3708
Nature communications 2018 Sep 13;9(1):3708
Ythdf2-mediated m6A mRNA clearance modulates neural development in mice.
Li M, Zhao X, Wang W, Shi H, Pan Q, Lu Z, Perez SP, Suganthan R, He C, Bjørås M, Klungland A
Genome biology 2018 May 31;19(1):69
Genome biology 2018 May 31;19(1):69
Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement.
Emmerson E, May AJ, Berthoin L, Cruz-Pacheco N, Nathan S, Mattingly AJ, Chang JL, Ryan WR, Tward AD, Knox SM
EMBO molecular medicine 2018 Mar;10(3)
EMBO molecular medicine 2018 Mar;10(3)
Nitrosative damage during retrovirus infection-induced neuropathic pain.
Chauhan P, Sheng WS, Hu S, Prasad S, Lokensgard JR
Journal of neuroinflammation 2018 Mar 5;15(1):66
Journal of neuroinflammation 2018 Mar 5;15(1):66
Control of neurite growth and guidance by an inhibitory cell-body signal.
Bicknell BA, Pujic Z, Dayan P, Goodhill GJ
PLoS computational biology 2018 Jun;14(6):e1006218
PLoS computational biology 2018 Jun;14(6):e1006218
Parkinson's disease genetic risk in a midbrain neuronal cell line.
Pierce SE, Tyson T, Booms A, Prahl J, Coetzee GA
Neurobiology of disease 2018 Jun;114:53-64
Neurobiology of disease 2018 Jun;114:53-64
Neurturin Gene Therapy Protects Parasympathetic Function to Prevent Irradiation-Induced Murine Salivary Gland Hypofunction.
Ferreira JNA, Zheng C, Lombaert IMA, Goldsmith CM, Cotrim AP, Symonds JM, Patel VN, Hoffman MP
Molecular therapy. Methods & clinical development 2018 Jun 15;9:172-180
Molecular therapy. Methods & clinical development 2018 Jun 15;9:172-180
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease.
Ludtmann MHR, Angelova PR, Horrocks MH, Choi ML, Rodrigues M, Baev AY, Berezhnov AV, Yao Z, Little D, Banushi B, Al-Menhali AS, Ranasinghe RT, Whiten DR, Yapom R, Dolt KS, Devine MJ, Gissen P, Kunath T, Jaganjac M, Pavlov EV, Klenerman D, Abramov AY, Gandhi S
Nature communications 2018 Jun 12;9(1):2293
Nature communications 2018 Jun 12;9(1):2293
The guanine nucleotide exchange factor Arhgef7/βPix promotes axon formation upstream of TC10.
López Tobón A, Suresh M, Jin J, Vitriolo A, Pietralla T, Tedford K, Bossenz M, Mahnken K, Kiefer F, Testa G, Fischer KD, Püschel AW
Scientific reports 2018 Jun 11;8(1):8811
Scientific reports 2018 Jun 11;8(1):8811
RIP2 Gates TRAF6 Interaction with Death Receptor p75NTR to Regulate Cerebellar Granule Neuron Survival.
Kisiswa L, Fernández-Suárez D, Sergaki MC, Ibáñez CF
Cell reports 2018 Jul 24;24(4):1013-1024
Cell reports 2018 Jul 24;24(4):1013-1024
Multicolor quantitative confocal imaging cytometry.
Coutu DL, Kokkaliaris KD, Kunz L, Schroeder T
Nature methods 2018 Jan;15(1):39-46
Nature methods 2018 Jan;15(1):39-46
Preclinical analysis of MTOR complex 1/2 inhibition in diffuse intrinsic pontine glioma.
Flannery PC, DeSisto JA, Amani V, Venkataraman S, Lemma RT, Prince EW, Donson A, Moroze EE, Hoffman L, Levy JMM, Foreman N, Vibhakar R, Green AL
Oncology reports 2018 Feb;39(2):455-464
Oncology reports 2018 Feb;39(2):455-464
Mitochondrial transfer from mesenchymal stem cells to neural stem cells protects against the neurotoxic effects of cisplatin.
Boukelmoune N, Chiu GS, Kavelaars A, Heijnen CJ
Acta neuropathologica communications 2018 Dec 12;6(1):139
Acta neuropathologica communications 2018 Dec 12;6(1):139
Distribution and Neurochemistry of the Porcine Ileocaecal Valve Projecting Sensory Neurons in the Dorsal Root Ganglia and the Influence of Lipopolysaccharide from Different Serotypes of Salmonella spp. on the Chemical Coding of DRG Neurons in the Cell Cultures.
Mikołajczyk A, Kozłowska A, Gonkowski S
International journal of molecular sciences 2018 Aug 28;19(9)
International journal of molecular sciences 2018 Aug 28;19(9)
The plasticity of primary microglia and their multifaceted effects on endogenous neural stem cells in vitro and in vivo.
Vay SU, Flitsch LJ, Rabenstein M, Rogall R, Blaschke S, Kleinhaus J, Reinert N, Bach A, Fink GR, Schroeter M, Rueger MA
Journal of neuroinflammation 2018 Aug 13;15(1):226
Journal of neuroinflammation 2018 Aug 13;15(1):226
Characterization of calcium signals in human induced pluripotent stem cell-derived dentate gyrus neuronal progenitors and mature neurons, stably expressing an advanced calcium indicator protein.
Vőfély G, Berecz T, Szabó E, Szebényi K, Hathy E, Orbán TI, Sarkadi B, Homolya L, Marchetto MC, Réthelyi JM, Apáti Á
Molecular and cellular neurosciences 2018 Apr;88:222-230
Molecular and cellular neurosciences 2018 Apr;88:222-230
Uncovering inherent cellular plasticity of multiciliated ependyma leading to ventricular wall transformation and hydrocephalus.
Abdi K, Lai CH, Paez-Gonzalez P, Lay M, Pyun J, Kuo CT
Nature communications 2018 Apr 25;9(1):1655
Nature communications 2018 Apr 25;9(1):1655
Embryonic Stem Cell-Derived Neurons Grown on Multi-Electrode Arrays as a Novel In vitro Bioassay for the Detection of Clostridium botulinum Neurotoxins.
Jenkinson SP, Grandgirard D, Heidemann M, Tscherter A, Avondet MA, Leib SL
Frontiers in pharmacology 2017;8:73
Frontiers in pharmacology 2017;8:73
Formation and spreading of TDP-43 aggregates in cultured neuronal and glial cells demonstrated by time-lapse imaging.
Ishii T, Kawakami E, Endo K, Misawa H, Watabe K
PloS one 2017;12(6):e0179375
PloS one 2017;12(6):e0179375
Time-Dependent, HIV-Tat-Induced Perturbation of Human Neurons In Vitro: Towards a Model for the Molecular Pathology of HIV-Associated Neurocognitive Disorders.
Gurwitz KT, Burman RJ, Murugan BD, Garnett S, Ganief T, Soares NC, Raimondo JV, Blackburn JM
Frontiers in molecular neuroscience 2017;10:163
Frontiers in molecular neuroscience 2017;10:163
Molecular and Functional Properties of Regional Astrocytes in the Adult Brain.
Morel L, Chiang MSR, Higashimori H, Shoneye T, Iyer LK, Yelick J, Tai A, Yang Y
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Sep 6;37(36):8706-8717
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Sep 6;37(36):8706-8717
Neuronal cells derived from human induced pluripotent stem cells as a functional tool of melanocortin system.
Yamada-Goto N, Ochi Y, Katsuura G, Yamashita Y, Ebihara K, Noguchi M, Fujikura J, Taura D, Sone M, Hosoda K, Gottschall PE, Nakao K
Neuropeptides 2017 Oct;65:10-20
Neuropeptides 2017 Oct;65:10-20
Alpha-synuclein facilitates to form short unconventional microtubules that have a unique function in the axonal transport.
Toba S, Jin M, Yamada M, Kumamoto K, Matsumoto S, Yasunaga T, Fukunaga Y, Miyazawa A, Fujita S, Itoh K, Fushiki S, Kojima H, Wanibuchi H, Arai Y, Nagai T, Hirotsune S
Scientific reports 2017 Nov 27;7(1):16386
Scientific reports 2017 Nov 27;7(1):16386
Enforcement of developmental lineage specificity by transcription factor Oct1.
Shen Z, Kang J, Shakya A, Tabaka M, Jarboe EA, Regev A, Tantin D
eLife 2017 May 24;6
eLife 2017 May 24;6
Vulnerability of primary neurons derived from Tg2576 Alzheimer mice to oxygen and glucose deprivation: role of intraneuronal amyloid-β accumulation and astrocytes.
Baldassarro VA, Marchesini A, Giardino L, Calzà L
Disease models & mechanisms 2017 May 1;10(5):671-678
Disease models & mechanisms 2017 May 1;10(5):671-678
PEGylated insulin-like growth factor-I affords protection and facilitates recovery of lost functions post-focal ischemia.
Parker K, Berretta A, Saenger S, Sivaramakrishnan M, Shirley SA, Metzger F, Clarkson AN
Scientific reports 2017 Mar 21;7(1):241
Scientific reports 2017 Mar 21;7(1):241
An Immortalized Human Dorsal Root Ganglion Cell Line Provides a Novel Context To Study Herpes Simplex Virus 1 Latency and Reactivation.
Thellman NM, Botting C, Madaj Z, Triezenberg SJ
Journal of virology 2017 Jun 15;91(12)
Journal of virology 2017 Jun 15;91(12)
FGF signaling refines Wnt gradients to regulate the patterning of taste papillae.
Prochazkova M, Häkkinen TJ, Prochazka J, Spoutil F, Jheon AH, Ahn Y, Krumlauf R, Jernvall J, Klein OD
Development (Cambridge, England) 2017 Jun 15;144(12):2212-2221
Development (Cambridge, England) 2017 Jun 15;144(12):2212-2221
PARP activity and inhibition in fetal and adult oligodendrocyte precursor cells: Effect on cell survival and differentiation.
Baldassarro VA, Marchesini A, Giardino L, Calzà L
Stem cell research 2017 Jul;22:54-60
Stem cell research 2017 Jul;22:54-60
IL-20 promotes epithelial healing of the injured mouse cornea.
Zhang W, Magadi S, Li Z, Smith CW, Burns AR
Experimental eye research 2017 Jan;154:22-29
Experimental eye research 2017 Jan;154:22-29
A novel role for the DNA repair gene Rad51 in Netrin-1 signalling.
Glendining KA, Markie D, Gardner RJ, Franz EA, Robertson SP, Jasoni CL
Scientific reports 2017 Jan 6;7:39823
Scientific reports 2017 Jan 6;7:39823
Modulated DISP3/PTCHD2 expression influences neural stem cell fate decisions.
Konířová J, Oltová J, Corlett A, Kopycińska J, Kolář M, Bartůněk P, Zíková M
Scientific reports 2017 Jan 30;7:41597
Scientific reports 2017 Jan 30;7:41597
Poly(ADP-ribose) polymerase inhibitors activate the p53 signaling pathway in neural stem/progenitor cells.
Okuda A, Kurokawa S, Takehashi M, Maeda A, Fukuda K, Kubo Y, Nogusa H, Takatani-Nakase T, Okuda S, Ueda K, Tanaka S
BMC neuroscience 2017 Jan 17;18(1):14
BMC neuroscience 2017 Jan 17;18(1):14
Cytosine-5 RNA Methylation Regulates Neural Stem Cell Differentiation and Motility.
Flores JV, Cordero-Espinoza L, Oeztuerk-Winder F, Andersson-Rolf A, Selmi T, Blanco S, Tailor J, Dietmann S, Frye M
Stem cell reports 2017 Jan 10;8(1):112-124
Stem cell reports 2017 Jan 10;8(1):112-124
FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1.
Hirano K, Namihira M
FEBS open bio 2017 Dec;7(12):1932-1942
FEBS open bio 2017 Dec;7(12):1932-1942
Genome Stability by DNA Polymerase β in Neural Progenitors Contributes to Neuronal Differentiation in Cortical Development.
Onishi K, Uyeda A, Shida M, Hirayama T, Yagi T, Yamamoto N, Sugo N
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Aug 30;37(35):8444-8458
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Aug 30;37(35):8444-8458
Inhibition of Wnt/β-catenin signaling by IWR1 induces expression of Foxd3 to promote mouse epiblast stem cell self-renewal.
Liu K, Sun Y, Liu D, Ye S
Biochemical and biophysical research communications 2017 Aug 26;490(3):616-622
Biochemical and biophysical research communications 2017 Aug 26;490(3):616-622
HDAC3 inhibition ameliorates spinal cord injury by immunomodulation.
Kuboyama T, Wahane S, Huang Y, Zhou X, Wong JK, Koemeter-Cox A, Martini M, Friedel RH, Zou H
Scientific reports 2017 Aug 17;7(1):8641
Scientific reports 2017 Aug 17;7(1):8641
Zeb2 is a negative regulator of midbrain dopaminergic axon growth and target innervation.
Hegarty SV, Wyatt SL, Howard L, Stappers E, Huylebroeck D, Sullivan AM, O'Keeffe GW
Scientific reports 2017 Aug 17;7(1):8568
Scientific reports 2017 Aug 17;7(1):8568
NOTCH1-Dependent Nitric Oxide Signaling Deficiency in Hypoplastic Left Heart Syndrome Revealed Through Patient-Specific Phenotypes Detected in Bioengineered Cardiogenesis.
Hrstka SC, Li X, Nelson TJ, Wanek Program Genetics Pipeline Group.
Stem cells (Dayton, Ohio) 2017 Apr;35(4):1106-1119
Stem cells (Dayton, Ohio) 2017 Apr;35(4):1106-1119
Lineage-Specific Differentiation Is Influenced by State of Human Pluripotency.
Lee JH, Laronde S, Collins TJ, Shapovalova Z, Tanasijevic B, McNicol JD, Fiebig-Comyn A, Benoit YD, Lee JB, Mitchell RR, Bhatia M
Cell reports 2017 Apr 4;19(1):20-35
Cell reports 2017 Apr 4;19(1):20-35
An Activating STAT3 Mutation Causes Neonatal Diabetes through Premature Induction of Pancreatic Differentiation.
Saarimäki-Vire J, Balboa D, Russell MA, Saarikettu J, Kinnunen M, Keskitalo S, Malhi A, Valensisi C, Andrus C, Eurola S, Grym H, Ustinov J, Wartiovaara K, Hawkins RD, Silvennoinen O, Varjosalo M, Morgan NG, Otonkoski T
Cell reports 2017 Apr 11;19(2):281-294
Cell reports 2017 Apr 11;19(2):281-294
Transfer of pathogenic and nonpathogenic cytosolic proteins between spinal cord motor neurons in vivo in chimeric mice.
Thomas EV, Fenton WA, McGrath J, Horwich AL
Proceedings of the National Academy of Sciences of the United States of America 2017 Apr 11;114(15):E3139-E3148
Proceedings of the National Academy of Sciences of the United States of America 2017 Apr 11;114(15):E3139-E3148
Repeated removal of developing limb buds permanently reduces appendage size in the highly-regenerative axolotl.
Bryant DM, Sousounis K, Farkas JE, Bryant S, Thao N, Guzikowski AR, Monaghan JR, Levin M, Whited JL
Developmental biology 2017 Apr 1;424(1):1-9
Developmental biology 2017 Apr 1;424(1):1-9
Generation of a TLE3 heterozygous knockout human embryonic stem cell line using CRISPR-Cas9.
Bara AM, Messana A, Herring A, Hazelbaker DZ, Eggan K, Barrett LE
Stem cell research 2016 Sep;17(2):441-443
Stem cell research 2016 Sep;17(2):441-443
Generation of a TLE1 homozygous knockout human embryonic stem cell line using CRISPR-Cas9.
Herring A, Messana A, Bara AM, Hazelbaker DZ, Eggan K, Barrett LE
Stem cell research 2016 Sep;17(2):430-432
Stem cell research 2016 Sep;17(2):430-432
Spinal cord injury induces astroglial conversion towards neuronal lineage.
Noristani HN, Sabourin JC, Boukhaddaoui H, Chan-Seng E, Gerber YN, Perrin FE
Molecular neurodegeneration 2016 Oct 6;11(1):68
Molecular neurodegeneration 2016 Oct 6;11(1):68
VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination.
Miyamoto Y, Torii T, Tanoue A, Yamauchi J
Nature communications 2016 Nov 23;7:13478
Nature communications 2016 Nov 23;7:13478
FGF8 and SHH substitute for anterior-posterior tissue interactions to induce limb regeneration.
Nacu E, Gromberg E, Oliveira CR, Drechsel D, Tanaka EM
Nature 2016 May 19;533(7603):407-10
Nature 2016 May 19;533(7603):407-10
Selective Deletion of Astroglial FMRP Dysregulates Glutamate Transporter GLT1 and Contributes to Fragile X Syndrome Phenotypes In Vivo.
Higashimori H, Schin CS, Chiang MS, Morel L, Shoneye TA, Nelson DL, Yang Y
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Jul 6;36(27):7079-94
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Jul 6;36(27):7079-94
The Severity of Infection Determines the Localization of Damage and Extent of Sensorineural Hearing Loss in Experimental Pneumococcal Meningitis.
Perny M, Roccio M, Grandgirard D, Solyga M, Senn P, Leib SL
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Jul 20;36(29):7740-9
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Jul 20;36(29):7740-9
A system for studying mechanisms of neuromuscular junction development and maintenance.
Vilmont V, Cadot B, Ouanounou G, Gomes ER
Development (Cambridge, England) 2016 Jul 1;143(13):2464-77
Development (Cambridge, England) 2016 Jul 1;143(13):2464-77
Retinoic-acid-mediated HRas stabilization induces neuronal differentiation of neural stem cells during brain development.
Park JC, Jeong WJ, Kim MY, Min D, Choi KY
Journal of cell science 2016 Aug 1;129(15):2997-3007
Journal of cell science 2016 Aug 1;129(15):2997-3007
An Engineered N-Cadherin Substrate for Differentiation, Survival, and Selection of Pluripotent Stem Cell-Derived Neural Progenitors.
Haque A, Adnan N, Motazedian A, Akter F, Hossain S, Kutsuzawa K, Nag K, Kobatake E, Akaike T
PloS one 2015;10(8):e0135170
PloS one 2015;10(8):e0135170
Attenuation of progressive hearing loss in DBA/2J mice by reagents that affect epigenetic modifications is associated with up-regulation of the zinc importer Zip4.
Mutai H, Miya F, Fujii M, Tsunoda T, Matsunaga T
PloS one 2015;10(4):e0124301
PloS one 2015;10(4):e0124301
Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression.
Aubry S, Shin W, Crary JF, Lefort R, Qureshi YH, Lefebvre C, Califano A, Shelanski ML
PloS one 2015;10(3):e0120352
PloS one 2015;10(3):e0120352
Angiogenesis in the developing spinal cord: blood vessel exclusion from neural progenitor region is mediated by VEGF and its antagonists.
Takahashi T, Takase Y, Yoshino T, Saito D, Tadokoro R, Takahashi Y
PloS one 2015;10(1):e0116119
PloS one 2015;10(1):e0116119
Signalling Through Retinoic Acid Receptors is Required for Reprogramming of Both Mouse Embryonic Fibroblast Cells and Epiblast Stem Cells to Induced Pluripotent Stem Cells.
Yang J, Wang W, Ooi J, Campos LS, Lu L, Liu P
Stem cells (Dayton, Ohio) 2015 May;33(5):1390-404
Stem cells (Dayton, Ohio) 2015 May;33(5):1390-404
Secreted ectodomain of sialic acid-binding Ig-like lectin-9 and monocyte chemoattractant protein-1 promote recovery after rat spinal cord injury by altering macrophage polarity.
Matsubara K, Matsushita Y, Sakai K, Kano F, Kondo M, Noda M, Hashimoto N, Imagama S, Ishiguro N, Suzumura A, Ueda M, Furukawa K, Yamamoto A
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Feb 11;35(6):2452-64
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Feb 11;35(6):2452-64
A simple and robust method for establishing homogeneous mouse epiblast stem cell lines by wnt inhibition.
Sugimoto M, Kondo M, Koga Y, Shiura H, Ikeda R, Hirose M, Ogura A, Murakami A, Yoshiki A, Chuva de Sousa Lopes SM, Abe K
Stem cell reports 2015 Apr 14;4(4):744-57
Stem cell reports 2015 Apr 14;4(4):744-57
Activated CD8+ T lymphocytes inhibit neural stem/progenitor cell proliferation: role of interferon-gamma.
Hu S, Rotschafer JH, Lokensgard JR, Cheeran MC
PloS one 2014;9(8):e105219
PloS one 2014;9(8):e105219
CaMKK-CaMK1a, a new post-traumatic signalling pathway induced in mouse somatosensory neurons.
Elzière L, Sar C, Ventéo S, Bourane S, Puech S, Sonrier C, Boukhadaoui H, Fichard A, Pattyn A, Valmier J, Carroll P, Méchaly I
PloS one 2014;9(5):e97736
PloS one 2014;9(5):e97736
Rapid and efficient conversion of integration-free human induced pluripotent stem cells to GMP-grade culture conditions.
Durruthy-Durruthy J, Briggs SF, Awe J, Ramathal CY, Karumbayaram S, Lee PC, Heidmann JD, Clark A, Karakikes I, Loh KM, Wu JC, Hoffman AR, Byrne J, Reijo Pera RA, Sebastiano V
PloS one 2014;9(4):e94231
PloS one 2014;9(4):e94231
Molecular and cellular features of murine craniofacial and trunk neural crest cells as stem cell-like cells.
Hagiwara K, Obayashi T, Sakayori N, Yamanishi E, Hayashi R, Osumi N, Nakazawa T, Nishida K
PloS one 2014;9(1):e84072
PloS one 2014;9(1):e84072
Diet-induced obesity and low testosterone increase neuroinflammation and impair neural function.
Jayaraman A, Lent-Schochet D, Pike CJ
Journal of neuroinflammation 2014 Sep 16;11:162
Journal of neuroinflammation 2014 Sep 16;11:162
Axolotls with an under- or oversupply of neural crest can regulate the sizes of their dorsal root ganglia to normal levels.
Zarzosa A, Grassme K, Tanaka E, Taniguchi Y, Bramke S, Kurth T, Epperlein H
Developmental biology 2014 Oct 1;394(1):65-82
Developmental biology 2014 Oct 1;394(1):65-82
Stage-dependent requirement of neuroretinal Pax6 for lens and retina development.
Klimova L, Kozmik Z
Development (Cambridge, England) 2014 Mar;141(6):1292-302
Development (Cambridge, England) 2014 Mar;141(6):1292-302
Intrinsically active and pacemaker neurons in pluripotent stem cell-derived neuronal populations.
Illes S, Jakab M, Beyer F, Gelfert R, Couillard-Despres S, Schnitzler A, Ritter M, Aigner L
Stem cell reports 2014 Mar 11;2(3):323-36
Stem cell reports 2014 Mar 11;2(3):323-36
ADAM metalloproteases promote a developmental switch in responsiveness to the axonal repellant Sema3A.
Romi E, Gokhman I, Wong E, Antonovsky N, Ludwig A, Sagi I, Saftig P, Tessier-Lavigne M, Yaron A
Nature communications 2014 Jun 5;5:4058
Nature communications 2014 Jun 5;5:4058
Senescence impairs direct conversion of human somatic cells to neurons.
Sun CK, Zhou D, Zhang Z, He L, Zhang F, Wang X, Yuan J, Chen Q, Wu LG, Yang Q
Nature communications 2014 Jun 17;5:4112
Nature communications 2014 Jun 17;5:4112
Maternal obesity and IL-6 lead to aberrant developmental gene expression and deregulated neurite growth in the fetal arcuate nucleus.
Sanders TR, Kim DW, Glendining KA, Jasoni CL
Endocrinology 2014 Jul;155(7):2566-77
Endocrinology 2014 Jul;155(7):2566-77
Netrin-1 controls sympathetic arterial innervation.
Brunet I, Gordon E, Han J, Cristofaro B, Broqueres-You D, Liu C, Bouvrée K, Zhang J, del Toro R, Mathivet T, Larrivée B, Jagu J, Pibouin-Fragner L, Pardanaud L, Machado MJ, Kennedy TE, Zhuang Z, Simons M, Levy BI, Tessier-Lavigne M, Grenz A, Eltzschig H, Eichmann A
The Journal of clinical investigation 2014 Jul;124(7):3230-40
The Journal of clinical investigation 2014 Jul;124(7):3230-40
Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression.
Ferrarese R, Harsh GR 4th, Yadav AK, Bug E, Maticzka D, Reichardt W, Dombrowski SM, Miller TE, Masilamani AP, Dai F, Kim H, Hadler M, Scholtens DM, Yu IL, Beck J, Srinivasasainagendra V, Costa F, Baxan N, Pfeifer D, von Elverfeldt D, Backofen R, Weyerbrock A, Duarte CW, He X, Prinz M, Chandler JP, Vogel H, Chakravarti A, Rich JN, Carro MS, Bredel M
The Journal of clinical investigation 2014 Jul;124(7):2861-76
The Journal of clinical investigation 2014 Jul;124(7):2861-76
Growth arrest and forced differentiation of human primary glioblastoma multiforme by a novel small molecule.
Kang TW, Choi SW, Yang SR, Shin TH, Kim HS, Yu KR, Hong IS, Ro S, Cho JM, Kang KS
Scientific reports 2014 Jul 3;4:5546
Scientific reports 2014 Jul 3;4:5546
Absence of lipofuscin in motor neurons of SOD1-linked ALS mice.
Bandyopadhyay U, Nagy M, Fenton WA, Horwich AL
Proceedings of the National Academy of Sciences of the United States of America 2014 Jul 29;111(30):11055-60
Proceedings of the National Academy of Sciences of the United States of America 2014 Jul 29;111(30):11055-60
Cytokine secretion from brain macrophages infected with human immunodeficiency virus in vitro and treated with raltegravir.
Tatro ET, Soontornniyomkij B, Letendre SL, Achim CL
BMC infectious diseases 2014 Jul 11;14:386
BMC infectious diseases 2014 Jul 11;14:386
Influence of biological matrix and artificial electrospun scaffolds on proliferation, differentiation and trophic factor synthesis of rat embryonic stem cells.
Alessandri M, Lizzo G, Gualandi C, Mangano C, Giuliani A, Focarete ML, Calzà L
Matrix biology : journal of the International Society for Matrix Biology 2014 Jan;33:68-76
Matrix biology : journal of the International Society for Matrix Biology 2014 Jan;33:68-76
Nogo receptor homolog NgR2 expressed in sensory DRG neurons controls epidermal innervation by interaction with Versican.
Bäumer BE, Kurz A, Borrie SC, Sickinger S, Dours-Zimmermann MT, Zimmermann DR, Bandtlow CE
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Jan 29;34(5):1633-46
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Jan 29;34(5):1633-46
Developmental regulation of trigeminal TRPA1 by the cornea.
Canner JP, Linsenmayer TF, Kubilus JK
Investigative ophthalmology & visual science 2014 Dec 11;56(1):29-36
Investigative ophthalmology & visual science 2014 Dec 11;56(1):29-36
Molecular evidence for OCT4-induced plasticity in adult human fibroblasts required for direct cell fate conversion to lineage specific progenitors.
Mitchell R, Szabo E, Shapovalova Z, Aslostovar L, Makondo K, Bhatia M
Stem cells (Dayton, Ohio) 2014 Aug;32(8):2178-87
Stem cells (Dayton, Ohio) 2014 Aug;32(8):2178-87
ERK2 suppresses self-renewal capacity of embryonic stem cells, but is not required for multi-lineage commitment.
Hamilton WB, Kaji K, Kunath T
PloS one 2013;8(4):e60907
PloS one 2013;8(4):e60907
Lamin A/C haploinsufficiency modulates the differentiation potential of mouse embryonic stem cells.
Sehgal P, Chaturvedi P, Kumaran RI, Kumar S, Parnaik VK
PloS one 2013;8(2):e57891
PloS one 2013;8(2):e57891
Genetic deletion of afadin causes hydrocephalus by destruction of adherens junctions in radial glial and ependymal cells in the midbrain.
Yamamoto H, Maruo T, Majima T, Ishizaki H, Tanaka-Okamoto M, Miyoshi J, Mandai K, Takai Y
PloS one 2013;8(11):e80356
PloS one 2013;8(11):e80356
Parasympathetic stimulation improves epithelial organ regeneration.
Knox SM, Lombaert IM, Haddox CL, Abrams SR, Cotrim A, Wilson AJ, Hoffman MP
Nature communications 2013;4:1494
Nature communications 2013;4:1494
ProNGF promotes neurite growth from a subset of NGF-dependent neurons by a p75NTR-dependent mechanism.
Howard L, Wyatt S, Nagappan G, Davies AM
Development (Cambridge, England) 2013 May;140(10):2108-17
Development (Cambridge, England) 2013 May;140(10):2108-17
Communication between corneal epithelial cells and trigeminal neurons is facilitated by purinergic (P2) and glutamatergic receptors.
Oswald DJ, Lee A, Trinidad M, Chi C, Ren R, Rich CB, Trinkaus-Randall V
PloS one 2012;7(9):e44574
PloS one 2012;7(9):e44574
Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embryonic stem cells from refractory mouse strains.
Ye S, Tan L, Yang R, Fang B, Qu S, Schulze EN, Song H, Ying Q, Li P
PloS one 2012;7(4):e35892
PloS one 2012;7(4):e35892
In vivo generation of neural tumors from neoplastic pluripotent stem cells models early human pediatric brain tumor formation.
Werbowetski-Ogilvie TE, Morrison LC, Fiebig-Comyn A, Bhatia M
Stem cells (Dayton, Ohio) 2012 Mar;30(3):392-404
Stem cells (Dayton, Ohio) 2012 Mar;30(3):392-404
IL-17 and VEGF are necessary for efficient corneal nerve regeneration.
Li Z, Burns AR, Han L, Rumbaut RE, Smith CW
The American journal of pathology 2011 Mar;178(3):1106-16
The American journal of pathology 2011 Mar;178(3):1106-16
Astrocyte-derived interleukin-6 promotes specific neuronal differentiation of neural progenitor cells from adult hippocampus.
Oh J, McCloskey MA, Blong CC, Bendickson L, Nilsen-Hamilton M, Sakaguchi DS
Journal of neuroscience research 2010 Oct;88(13):2798-809
Journal of neuroscience research 2010 Oct;88(13):2798-809
Pig epiblast stem cells depend on activin/nodal signaling for pluripotency and self-renewal.
Alberio R, Croxall N, Allegrucci C
Stem cells and development 2010 Oct;19(10):1627-36
Stem cells and development 2010 Oct;19(10):1627-36
A fusion protein N-cadherin-Fc as an artificial extracellular matrix surface for maintenance of stem cell features.
Yue XS, Murakami Y, Tamai T, Nagaoka M, Cho CS, Ito Y, Akaike T
Biomaterials 2010 Jul;31(20):5287-96
Biomaterials 2010 Jul;31(20):5287-96
Synovial sarcoma is a stem cell malignancy.
Naka N, Takenaka S, Araki N, Miwa T, Hashimoto N, Yoshioka K, Joyama S, Hamada K, Tsukamoto Y, Tomita Y, Ueda T, Yoshikawa H, Itoh K
Stem cells (Dayton, Ohio) 2010 Jul;28(7):1119-31
Stem cells (Dayton, Ohio) 2010 Jul;28(7):1119-31
Presence of pluripotent CD133+ cells correlates with malignancy of gliomas.
Thon N, Damianoff K, Hegermann J, Grau S, Krebs B, Schnell O, Tonn JC, Goldbrunner R
Molecular and cellular neurosciences 2010 Jan;43(1):51-9
Molecular and cellular neurosciences 2010 Jan;43(1):51-9
Developmental corneal innervation: interactions between nerves and specialized apical corneal epithelial cells.
Kubilus JK, Linsenmayer TF
Investigative ophthalmology & visual science 2010 Feb;51(2):782-9
Investigative ophthalmology & visual science 2010 Feb;51(2):782-9
Metastable primordial germ cell-like state induced from mouse embryonic stem cells by Akt activation.
Yamano N, Kimura T, Watanabe-Kushima S, Shinohara T, Nakano T
Biochemical and biophysical research communications 2010 Feb 12;392(3):311-6
Biochemical and biophysical research communications 2010 Feb 12;392(3):311-6
A defined glycosaminoglycan-binding substratum for human pluripotent stem cells.
Klim JR, Li L, Wrighton PJ, Piekarczyk MS, Kiessling LL
Nature methods 2010 Dec;7(12):989-94
Nature methods 2010 Dec;7(12):989-94
Developmental guidance of embryonic corneal innervation: roles of Semaphorin3A and Slit2.
Kubilus JK, Linsenmayer TF
Developmental biology 2010 Aug 1;344(1):172-84
Developmental biology 2010 Aug 1;344(1):172-84
Tumor microvasculature supports proliferation and expansion of glioma-propagating cells.
Borovski T, Verhoeff JJ, ten Cate R, Cameron K, de Vries NA, van Tellingen O, Richel DJ, van Furth WR, Medema JP, Sprick MR
International journal of cancer 2009 Sep 1;125(5):1222-30
International journal of cancer 2009 Sep 1;125(5):1222-30
Continuous exposure to 900MHz GSM-modulated EMF alters morphological maturation of neural cells.
Del Vecchio G, Giuliani A, Fernandez M, Mesirca P, Bersani F, Pinto R, Ardoino L, Lovisolo GA, Giardino L, Calzà L
Neuroscience letters 2009 May 22;455(3):173-7
Neuroscience letters 2009 May 22;455(3):173-7
Docosahexaenoic acid promotes neuronal differentiation by regulating basic helix-loop-helix transcription factors and cell cycle in neural stem cells.
Katakura M, Hashimoto M, Shahdat HM, Gamoh S, Okui T, Matsuzaki K, Shido O
Neuroscience 2009 May 19;160(3):651-60
Neuroscience 2009 May 19;160(3):651-60
Cells keep a memory of their tissue origin during axolotl limb regeneration.
Kragl M, Knapp D, Nacu E, Khattak S, Maden M, Epperlein HH, Tanaka EM
Nature 2009 Jul 2;460(7251):60-5
Nature 2009 Jul 2;460(7251):60-5
Survival, neuron-like differentiation and functionality of mesenchymal stem cells in neurotoxic environment: the critical role of erythropoietin.
Danielyan L, Schäfer R, Schulz A, Ladewig T, Lourhmati A, Buadze M, Schmitt AL, Verleysdonk S, Kabisch D, Koeppen K, Siegel G, Proksch B, Kluba T, Eckert A, Köhle C, Schöneberg T, Northoff H, Schwab M, Gleiter CH
Cell death and differentiation 2009 Dec;16(12):1599-614
Cell death and differentiation 2009 Dec;16(12):1599-614
Reticulon RTN2B regulates trafficking and function of neuronal glutamate transporter EAAC1.
Liu Y, Vidensky S, Ruggiero AM, Maier S, Sitte HH, Rothstein JD
The Journal of biological chemistry 2008 Mar 7;283(10):6561-71
The Journal of biological chemistry 2008 Mar 7;283(10):6561-71
Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease.
Boland B, Kumar A, Lee S, Platt FM, Wegiel J, Yu WH, Nixon RA
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Jul 2;28(27):6926-37
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Jul 2;28(27):6926-37
Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells.
Ruau D, Ensenat-Waser R, Dinger TC, Vallabhapurapu DS, Rolletschek A, Hacker C, Hieronymus T, Wobus AM, Müller AM, Zenke M
Stem cells (Dayton, Ohio) 2008 Apr;26(4):920-6
Stem cells (Dayton, Ohio) 2008 Apr;26(4):920-6
SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation.
Ai X, Kitazawa T, Do AT, Kusche-Gullberg M, Labosky PA, Emerson CP Jr
Development (Cambridge, England) 2007 Sep;134(18):3327-38
Development (Cambridge, England) 2007 Sep;134(18):3327-38
Triggering neural differentiation of ES cells by subtype switching of importin-alpha.
Yasuhara N, Shibazaki N, Tanaka S, Nagai M, Kamikawa Y, Oe S, Asally M, Kamachi Y, Kondoh H, Yoneda Y
Nature cell biology 2007 Jan;9(1):72-9
Nature cell biology 2007 Jan;9(1):72-9
Phosphorylated FTY720 promotes astrocyte migration through sphingosine-1-phosphate receptors.
Mullershausen F, Craveiro LM, Shin Y, Cortes-Cros M, Bassilana F, Osinde M, Wishart WL, Guerini D, Thallmair M, Schwab ME, Sivasankaran R, Seuwen K, Dev KK
Journal of neurochemistry 2007 Aug;102(4):1151-61
Journal of neurochemistry 2007 Aug;102(4):1151-61
The free-radical scavenger edaravone restores the differentiation of human neural precursor cells after radiation-induced oxidative stress.
Ishii J, Natsume A, Wakabayashi T, Takeuchi H, Hasegawa H, Kim SU, Yoshida J
Neuroscience letters 2007 Aug 23;423(3):225-30
Neuroscience letters 2007 Aug 23;423(3):225-30
Docosahexaenoic acid promotes neurogenesis in vitro and in vivo.
Kawakita E, Hashimoto M, Shido O
Neuroscience 2006;139(3):991-7
Neuroscience 2006;139(3):991-7
Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm.
Lindsley RC, Gill JG, Kyba M, Murphy TL, Murphy KM
Development (Cambridge, England) 2006 Oct;133(19):3787-96
Development (Cambridge, England) 2006 Oct;133(19):3787-96
Neurogenic effect of vascular endothelial growth factor during germ layer formation of human embryonic stem cells.
Kim BK, Kim SE, Shim JH, Woo DH, Gil JE, Kim SK, Kim JH
FEBS letters 2006 Oct 30;580(25):5869-74
FEBS letters 2006 Oct 30;580(25):5869-74
Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death.
Yamashita H, Nakamura T, Takahashi T, Nagano Y, Hiji M, Hirabayashi T, Amano T, Yagi T, Sakai N, Kohriyama T, Matsumoto M
Journal of neurochemistry 2006 Jul;98(1):45-56
Journal of neurochemistry 2006 Jul;98(1):45-56
Neural differentiation of embryonic stem cells induced by conditioned medium from neural stem cell.
Zhang JQ, Yu XB, Ma BF, Yu WH, Zhang AX, Huang G, Mao FF, Zhang XM, Wang ZC, Li SN, Lahn BT, Xiang AP
Neuroreport 2006 Jul 17;17(10):981-6
Neuroreport 2006 Jul 17;17(10):981-6
Isolation of multipotent neural crest-derived stem cells from the adult mouse cornea.
Yoshida S, Shimmura S, Nagoshi N, Fukuda K, Matsuzaki Y, Okano H, Tsubota K
Stem cells (Dayton, Ohio) 2006 Dec;24(12):2714-22
Stem cells (Dayton, Ohio) 2006 Dec;24(12):2714-22
Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages.
Porat Y, Porozov S, Belkin D, Shimoni D, Fisher Y, Belleli A, Czeiger D, Silverman WF, Belkin M, Battler A, Fulga V, Savion N
British journal of haematology 2006 Dec;135(5):703-14
British journal of haematology 2006 Dec;135(5):703-14
Predominant expression of GluR2 among the AMPA receptor subunits in neuronal progenitor cells of the rat hippocampus.
Hagimura N, Tsuzuki K, Iino M, Takatsuru Y, Yoshida Y, Kishi S, Ozawa S
Brain research. Developmental brain research 2004 Sep 17;152(2):213-23
Brain research. Developmental brain research 2004 Sep 17;152(2):213-23
High-level expression of functional chemokine receptor CXCR4 on human neural precursor cells.
Ni HT, Hu S, Sheng WS, Olson JM, Cheeran MC, Chan AS, Lokensgard JR, Peterson PK
Brain research. Developmental brain research 2004 Sep 17;152(2):159-69
Brain research. Developmental brain research 2004 Sep 17;152(2):159-69
6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase form a supramolecular complex in human neutrophils that undergoes retrograde trafficking during pregnancy.
Kindzelskii AL, Ueki T, Michibata H, Chaiworapongsa T, Romero R, Petty HR
Journal of immunology (Baltimore, Md. : 1950) 2004 May 15;172(10):6373-81
Journal of immunology (Baltimore, Md. : 1950) 2004 May 15;172(10):6373-81
6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase form a supramolecular complex in human neutrophils that undergoes retrograde trafficking during pregnancy.
Kindzelskii AL, Ueki T, Michibata H, Chaiworapongsa T, Romero R, Petty HR
Journal of immunology (Baltimore, Md. : 1950) 2004 May 15;172(10):6373-81
Journal of immunology (Baltimore, Md. : 1950) 2004 May 15;172(10):6373-81
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Supportive validation
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- Detection of Human and Mouse beta-III Tubulin by Western Blot. Western blot shows lysates of human brain (cerebellum) tissue, human brain (hypothalamus) tissue, mouse brain (cerebellum) tissue, and mouse brain (stem) tissue. PVDF membrane was probed with 0.2 µg/mL of Mouse Anti-Neuron-specific beta-III Tubulin Monoclonal Antibody (Catalog # MAB1195) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for beta-III Tubulin at approximately 55 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.
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- Detection of Rat beta-III Tubulin by Simple WesternTM. Simple Western lane view shows lysates of rat cortical neurons, loaded at 0.2 mg/mL. A specific band was detected for beta-III Tubulin at approximately 56 kDa (as indicated) using 10 µg/mL of Mouse Anti-Neuron-specific beta-III Tubulin Monoclonal Antibody (Catalog # MAB1195). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.
Supportive validation
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- beta-III Tubulin and Nestin in Rat Cortical Stem Cells. beta-III Tubulin and Nestin were detected in rat cortical stem cells (Catalog # NSC001) using 5 µg/mL neuron-specific Mouse Anti-Neuron-specific beta-III Tubulin Monoclonal Antibody (Catalog # MAB1195) and 10 µg/mL Rat Nestin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2736). Cells were incubated with primary antibodies for 3 hours at room temperature. Cells were stained for beta-III Tubulin using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and for Nestin using the NorthernLights 493-conjugated Anti-Goat IgG Secondary Antibody (green; Catalog # NL003). Tissue was counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.
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- Experimental details
- beta-III Tubulin in Rat Cortical Neurons and GFAP in Rat Astrocytes. beta-III Tubulin was detected in rat cortical neurons using 5 µg/mL neuron-specific Mouse Anti-Neuron-specific beta-III Tubulin Monoclonal Antibody (Catalog # MAB1195). GFAP was detected in rat astrocytes using 10 µg/mL Human GFAP Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2594). Cells were incubated with primary antibodies for 3 hours at room temperature. Cells were stained for beta-III Tubulin using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and for GFAP using the NorthernLights 493-conjugated Anti-Sheep IgG Secondary Antibody (green; Catalog # NL012). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.
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- R&D Systems (provider)
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- Experimental details
- beta-III Tubulin in Differentiated Human Neural Progenitor Cells. beta-III Tubulin was detected in immersion fixed differentiated human neural progenitor cells using Mouse Anti-Neuron-specific beta-III Tubulin Monoclonal Antibody (clone TuJ-1) (Catalog # MAB1195) for 3 hours at room temperature. Cells were stained (green) and counterstained (red). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.
Supportive validation
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- R&D Systems (provider)
- Main image
- Experimental details
- beta-III Tubulin in Human Brain. beta-III Tubulin was detected in immersion fixed paraffin-embedded sections of human brain (cerebellum) using Mouse Anti-Neuron-specific beta-III Tubulin Monoclonal Antibody (Catalog # MAB1195) at 8 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC001). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to Purkinje neurons. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.
