Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS9241 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- CD1e (D248) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 220-270 of Human CD1e.
- Description
- CD1E, also known as R2 or CD1A, is a 322 amino acid single-pass type I membrane protein that localizes to the lumen of the endoplasmic reticulum, as well as to the golgi apparatus, and contains one Ig-like domain. Expressed in a variety of tissues and on cortical thymocytes, dendritic cells and Langerhans cells, CD1E exists as a heterodimer with beta-2-Microglobulin and is necessary for the presentation of glycolipid antigens on the cell surface. CD1E is subject to post-translational mono-ubiquitination and may also be proteolytically cleaved in endosomes to yield a soluble protein. CD1E is present on the surface of some T-cell leukemias, suggesting a possible role in tumorigenesis.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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