Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Immunohistochemistry [7]
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- Product number
- NBP2-30551 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rabbit Polyclonal TMEM119 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human TMEM119 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Rat, Feline, Porcine
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Mesenchymal stem cell-derived magnetic extracellular nanovesicles for targeting and treatment of ischemic stroke.
Delayed Administration of Angiotensin II Type 2 Receptor (AT2R) Agonist Compound 21 Prevents the Development of Post-stroke Cognitive Impairment in Diabetes Through the Modulation of Microglia Polarization.
Microglia knockdown reduces inflammation and preserves cognition in diabetic animals after experimental stroke.
An immortalized microglial cell line (Mocha) derived from rat cochlea.
Kim HY, Kim TJ, Kang L, Kim YJ, Kang MK, Kim J, Ryu JH, Hyeon T, Yoon BW, Ko SB, Kim BS
Biomaterials 2020 Jun;243:119942
Biomaterials 2020 Jun;243:119942
Delayed Administration of Angiotensin II Type 2 Receptor (AT2R) Agonist Compound 21 Prevents the Development of Post-stroke Cognitive Impairment in Diabetes Through the Modulation of Microglia Polarization.
Jackson L, Dong G, Althomali W, Sayed MA, Eldahshan W, Baban B, Johnson MH, Filosa J, Fagan SC, Ergul A
Translational stroke research 2020 Aug;11(4):762-775
Translational stroke research 2020 Aug;11(4):762-775
Microglia knockdown reduces inflammation and preserves cognition in diabetic animals after experimental stroke.
Jackson L, Dumanli S, Johnson MH, Fagan SC, Ergul A
Journal of neuroinflammation 2020 Apr 28;17(1):137
Journal of neuroinflammation 2020 Apr 28;17(1):137
An immortalized microglial cell line (Mocha) derived from rat cochlea.
Seigel GM, Manohar S, Bai YY, Ding D, Salvi R
Molecular and cellular neurosciences 2017 Dec;85:202-210
Molecular and cellular neurosciences 2017 Dec;85:202-210
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30551] - Staining of human cerebral cortex shows weak positivity in microglia.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30551] - Staining of human liver shows no positivity in hepatocytes as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30551] - Staining of human lymph node shows moderate membranous positivity in germinal center cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30551] - Staining of human testis shows weak membranous positivity in cells in lamina propria.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30551] - Staining of human cerebral cortex, liver, lymph node and testis using Anti-TMEM119 antibody NBP2-30551 (A) shows similar protein distribution across tissues to independent antibody NBP2-30792 (B).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30551] - Staining in human lymph node and liver tissues. Corresponding TMEM119 RNA-seq data are presented for the same tissues.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30551] - Pig cerebral cortex. IHC image submitted by a verified customer review.