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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 24766-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- INSIG2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated INSIG2 antibody (Cat. #24766-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis.
p38α/S1P/SREBP2 activation by the SAM-competitive EZH2 inhibitor GSK343 limits its anticancer activity but creates a druggable vulnerability in hepatocellular carcinoma.
Xu D, Wang Z, Xia Y, Shao F, Xia W, Wei Y, Li X, Qian X, Lee JH, Du L, Zheng Y, Lv G, Leu JS, Wang H, Xing D, Liang T, Hung MC, Lu Z
Nature 2020 Apr;580(7804):530-535
Nature 2020 Apr;580(7804):530-535
p38α/S1P/SREBP2 activation by the SAM-competitive EZH2 inhibitor GSK343 limits its anticancer activity but creates a druggable vulnerability in hepatocellular carcinoma.
Yang PM, Hong YH, Hsu KC, Liu TP
American journal of cancer research 2019;9(10):2120-2139
American journal of cancer research 2019;9(10):2120-2139
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- rat liver tissue were subjected to SDS PAGE followed by western blot with 24766-1-AP( INSIG2 Antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The INSIG2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human INSIG2. This antibody recognizes human, mouse, rat antigen. The INSIG2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
