Antibody data
- Antibody Data
- Antigen structure
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- Validations [0]
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- Product number
- FNab04334 - Provider product page
- Provider
- FineTest Biotech
- Product name
- INSIG2 antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant protein fragment
- Description
- Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins(SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Antigen sequence
insulin induced gene 2
- Epitope
- IgG
- Isotype
- IgG
- Vial size
- 100¦Ìg
- Concentration
- Immunogen affinity purified
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
- Handling
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
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