Antibody data
- Product number
- ABIN953221
- Provider
- antibodies-online
- Product name
- anti-Leucine Rich Repeat Containing 4 (LRRC4) (AA 536-565), (C-Term) antibody
- Provider product page
- antibodies-online - ABIN953221
- Antibody type
- Polyclonal
- Description
- Protein A column, followed by peptide affinity purification
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 536-565, C-Term
- Vial size
- 0.4 mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Promoter hypermethylation-mediated inactivation of LRRC4 in gliomas.
Zhang Z, Li D, Wu M, Xiang B, Wang L, Zhou M, Chen P, Li X, Shen S, Li G
BMC molecular biology 2008 Nov 3;9:99
LRRC4 inhibits glioblastoma cell proliferation, migration, and angiogenesis by downregulating pleiotropic cytokine expression and responses.
Wu M, Huang C, Li X, Li X, Gan K, Chen Q, Tang Y, Tang K, Shen S, Li G
Journal of cellular physiology 2008 Jan;214(1):65-74
LRRC4, a putative tumor suppressor gene, requires a functional leucine-rich repeat cassette domain to inhibit proliferation of glioma cells in vitro by modulating the extracellular signal-regulated kinase/protein kinase B/nuclear factor-kappaB pathway.
Wu M, Huang C, Gan K, Huang H, Chen Q, Ouyang J, Tang Y, Li X, Yang Y, Zhou H, Zhou Y, Zeng Z, Xiao L, Li D, Tang K, Shen S, Li G
Molecular biology of the cell 2006 Aug;17(8):3534-42
Profiling of differentially expressed genes in LRRC4 overexpressed glioblastoma cells by cDNA array.
Zhang QH, Wu MH, Wang LL, Cao L, Tang K, Peng C, Gan K, Li XL, Li GY
Acta biochimica et biophysica Sinica 2005 Oct;37(10):680-7
Study of a novel brain relatively specific gene LRRC4 involved in glioma tumorigenesis suppression using the Tet-on system.
Zhang QH, Wang LL, Cao L, Peng C, Li XL, Tang K, Li WF, Liao P, Wang JR, Li GY
Acta biochimica et biophysica Sinica 2005 Aug;37(8):532-40
Supportive validation
- Submitted by
-
antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
-
antibodies-online (provider)
- Main image
- Experimental details
- IHC
Supportive data in Antibodypedia
