CLDN22

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3' UTR of the WWC2 gene (GeneID: 80014) on the opposite strand. [provided by RefSeq, Aug 2010]

Description

Claudin 22

Tissue specificity

Tissue enriched (salivary gland)

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Transporters

Chromosome

4 (183318100 - 183320276)

Ensembl ID

ENSG00000177300  (ver. 103.38)

Orthologs

-

UniProt

Q8N7P3

neXtProt

NX_Q8N7P3

Human splice variants

Protein structure