Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PA5-60876 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- HMCES Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- Immunogen sequence: WRLLTMAGIF DCWEPPEGGD VLYSYTIITV DSCKGLSDIH HRMPAILDGE EAVSKWLDFG EVSTQEALKL IHPTENITFH AVSSVVNNS
- Concentration
- 0.2 mg/mL
Submitted references Degradation of 5hmC-marked stalled replication forks by APE1 causes genomic instability.
Kharat SS, Ding X, Swaminathan D, Suresh A, Singh M, Sengodan SK, Burkett S, Marks H, Pamala C, He Y, Fox SD, Buehler EC, Muegge K, Martin SE, Sharan SK
Science signaling 2020 Aug 18;13(645)
Science signaling 2020 Aug 18;13(645)
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of HMCES in MCF-7 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using a HMCES Polyclonal Antibody (Product # PA5-60876). Remaining relative intensity is presented. Loading control: Anti-GAPDH.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of HMCES in human cell line U-2 OS shows positivity in nucleus. Samples were probed using a HMCES Polyclonal Antibody (Product # PA5-60876).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of HMCES in human testis using a HMCES Polyclonal Antibody (Product # PA5-60876) shows strong nuclear positivity in cells in seminiferous ducts.