MB0157

antibody from Bioworld Technology, Inc
Targeting: PPP1R18 KIAA1949, phostensin
Provider product page for MB0157

Antibody data

Product number
MB0157 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Phostensin monoclonal antibody
Antibody type
Monoclonal
Antigen
Recombinant full length Human Phostensin.
Description
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases, specifically PP1 (protein phosphhatase 1), which is targeted to different substrates throughout the cell. Phostensin, also known as KIAA1949, is a 613 amino acid protein that localizes to both the cytoplasm and the cytoskeleton. Expressed predominately in spleen, ovary, lung and liver tissue, phostensin functions as a regulatory subunit that interacts with and targets PP1 to F-Actin in the cytoskeleton. Two isoforms of phostensin exist due to alternative splicing events.
Reactivity
Human
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PPP1R18 protein structure - MB0157 shown in red.